- Conditions
- Left Atrail Appendage Closure: Peri-device Leaks
- Interventions
- leak closure with either detachable embolization coils, vascular plugs/CSO, or RFA
- Other
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
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Showing 1–24
of 31
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Cardiovascular Diseases
- Interventions
- No investigational intervention administered
- Other
- Lead sponsor
- Anumana, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 6
- States / cities
- Jonesboro, Arkansas • Boston, Massachusetts • New Bedford, Massachusetts + 3 more
- Conditions
- Non-valvular Atrial Fibrillation
- Interventions
- Left Atrial Appendage Closure
- Device
- Lead sponsor
- Biosense Webster, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 58 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 7
- States / cities
- Tucson, Arizona • Jonesboro, Arkansas • La Jolla, California + 3 more
- Conditions
- Non-Valvular Atrial Fibrillation, Left Atrial Appendage Closure
- Interventions
- Edoxaban, WATCHMAN LAA Closure, Aspirin and Clopidogrel, Aspirin and Warfarin
- Drug · Device
- Lead sponsor
- Scripps Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure
- Interventions
- Not listed
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 21 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Atrial Fibrillation, Bleeding, Stroke
- Interventions
- WATCHMAN FLX Pro LAAC Device
- Device
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 949 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 45
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 39 more
- Conditions
- Atrial Fibrillation, Stroke
- Interventions
- Imaging guidance with TEE and ICE for Left atrial appendage closure
- Device
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Atrial Fibrillation, Ischemic Stroke, Acute
- Interventions
- Left Atrial Appendage Occlusion
- Other
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Overland Park, Kansas
- Conditions
- Left Atrial Appendage Incomplete Closure
- Interventions
- Interlock-35 Fibered IDC Occlusion System, Concerto Helix Detachable Coil System, Azur Peripheral Coil System
- Device
- Lead sponsor
- Texas Cardiac Arrhythmia Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Atrial Fibrillation, Dementia, Cognitive Decline
- Interventions
- Questionnaire, Magnetic Resonance Imaging
- Other · Diagnostic Test
- Lead sponsor
- Intermountain Health Care, Inc.
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Murray, Utah
- Conditions
- Stroke
- Interventions
- Coherex WaveCrest® Left Atrial Appendage Occlusion System, Watchman® LAA Closure Device
- Device
- Lead sponsor
- Coherex Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 248 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 23
- States / cities
- Birmingham, Alabama • Chandler, Arizona • Los Angeles, California + 18 more
- Conditions
- Left Atrial Appendage Closure With WATCHMAN Device Utilizing an Intra-procedural ICE Probe
- Interventions
- WATCHMAN device implant procedure utilizing ICE probe
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 2
- States / cities
- Santa Monica, California • Rochester, Minnesota
- Conditions
- Atrial Fibrillation, Stroke, Bleeding, Leakage of Cardiac Device
- Interventions
- Peri-device leakage closure after left atrial appendage occlusion
- Device
- Lead sponsor
- Cardiovascular Center Frankfurt
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 7
- States / cities
- Phoenix, Arizona • La Jolla, California • Overland Park, Kansas + 4 more
- Conditions
- PFA Ablation and LAAC Procedures
- Interventions
- Watchman FLX™ Pro device.
- Device
- Lead sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 122 participants
- Timeline
- 2025 – 2026
- U.S. locations
- 15
- States / cities
- Birmingham, Alabama • San Francisco, California • Littleton, Colorado + 12 more
- Conditions
- Atrial Fibrillation, Stroke
- Interventions
- Left atrial appendage occlusion with the dual mechanism closure Amulet device using a novel steerable sheath.
- Other
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 7
- States / cities
- Overland Park, Kansas • Independence, Missouri • Kansas City, Missouri
- Conditions
- Cardioembolic Stroke, Atrial Fibrillation
- Interventions
- Left atrial appendage closure, SentreHeart Lariat®
- Procedure · Device
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Left Atrial Appendage Occlusion
- Interventions
- Medtronic LAA Occlusion Device
- Device
- Lead sponsor
- Medtronic Cardiovascular
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 5
- States / cities
- Rancho Mirage, California • New Haven, Connecticut • Chicago, Illinois + 2 more
- Conditions
- Cardiac Arrythmias, Left Atrial Appendage Closure
- Interventions
- Transseptal procedure with Agilis RF TSP System.
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 3
- States / cities
- Jonesboro, Arkansas • San Francisco, California • Kansas City, Missouri
- Conditions
- Atrial Fibrillation
- Interventions
- Aegis Sierra Ligation System
- Device
- Lead sponsor
- Aegis Medical Innovations
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2024
- U.S. locations
- 4
- States / cities
- Santa Monica, California • Rochester, Minnesota • New York, New York + 1 more
- Conditions
- Atrial Fibrillation, Stroke
- Interventions
- WATCHMAN Device, Warfarin
- Device · Drug
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 407 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2017
- U.S. locations
- 41
- States / cities
- Gilbert, Arizona • Scottsdale, Arizona • La Jolla, California + 35 more
- Conditions
- Left Atrial Appendage Closure
- Interventions
- Intracardiac Echocardiography, Traditional transesophageal echocardiography
- Device
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 444 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 1
- States / cities
- Plano, Texas
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Interventions
- WATCHMAN FLX Pro LAAC Device
- Device
- Lead sponsor
- Boston Scientific Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,857 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 86
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 78 more
- Conditions
- Atrial Fibrillation, Stroke, Bleeding
- Interventions
- Left atrial appendage occlusion (LAAO)
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 610 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 16
- States / cities
- Phoenix, Arizona • Little Rock, Arkansas • Jacksonville, Florida + 13 more
- Conditions
- Atrial Fibrillation, GI Bleeding
- Interventions
- LAAC with Watchman FLX device
- Device
- Lead sponsor
- Kansas City Heart Rhythm Research Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 73 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 4
- States / cities
- Overland Park, Kansas • Kansas City, Missouri