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ClinicalTrials.gov public records Last synced Oct 25, 2026, 7:58 AM EDT

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Showing 1–24 of 835 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Lens Diseases Clear all
Completed Not applicable Interventional Results available

Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism

NCT04676451
View directory record Official record
Conditions
Astigmatism, Cataract
Interventions
Femto-AK
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Progression After Ceasing Myopia Control Contact Lens Wear

NCT01829230
View directory record Official record
Conditions
Myopia
Interventions
1 Day Acuvue Moist
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
9 Years to 13 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Phase 4 Interventional

Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial

NCT01279031
View directory record Official record
Conditions
Cataracts, Astigmatism
Interventions
Abbott WHITESTAR Signature System with Ellips Transversal Ultrasound, Alcon Infiniti wiht the OZIL Torsional Handpiece
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2012 · Synced Oct 25, 2026, 7:58 AM EDT
Recruiting Phase 4 Interventional

Odyssey Evaluation in Post LASIK Patients

NCT07260695
View directory record Official record
Conditions
Cataract
Interventions
Odyssey intraocular lens
Device
Lead sponsor
Center For Sight
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Venice, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 25, 2026, 7:58 AM EDT
Completed No phase listed Observational

Comparison of Two Biometers in Dense Cataracts

NCT07475832
View directory record Official record
Conditions
Cataract
Interventions
ARGOS biometer, IOLMaster 700
Diagnostic Test
Lead sponsor
Berkeley Eye Center
Other
Eligibility
45 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance Comparison Between Comfilcon A and Senofilcon C Lenses

NCT02920957
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A, senofilcon C
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
5
States / cities
Whittier, California • Ocoee, Florida • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 9, 2018 · Synced Oct 25, 2026, 7:58 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of Lens Presentation on the Clinical Oculomotor Assessment at Near

NCT02679313
View directory record Official record
Conditions
Vision Disorders
Interventions
Phoropter
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 25, 2026, 7:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

NCT06335212
View directory record Official record
Conditions
Myopia, Refractive Errors, Contact Lens
Interventions
Single vision and multifocal contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 28, 2024 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conjunctival Rebound After Scleral Lens Wear

NCT04340518
View directory record Official record
Conditions
Conjunctival Diseases
Interventions
Scleral lens
Device
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2021 · Synced Oct 25, 2026, 7:58 AM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Safety Study of IBI-10090 in Cataract Surgery Patients

NCT01214174
View directory record Official record
Conditions
Ocular Inflammation
Interventions
IBI-10090
Drug
Lead sponsor
ICON Bioscience Inc
Industry
Eligibility
40 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 18, 2013 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Results available

Initial Performance of a Daily Disposable Contact Lens Featuring Molded Marks

NCT02939170
View directory record Official record
Conditions
Refractive Error
Interventions
Delefilcon A Multifocal Contact Lenses with Molded Mark, Delefilcon A Multifocal Contact Lenses
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
View directory record Official record
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 25, 2026, 7:58 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Intraoperative OCT Guidance of Intraocular Surgery II

NCT03713268
View directory record Official record
Conditions
Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment, Retinal Disease, Preretinal Fibrosis, Cataract, Ocular Tumor, Strabismus, Healthy
Interventions
Microscope integrated optical coherence tomography
Device
Lead sponsor
Duke University
Other
Eligibility
4 Weeks and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 25, 2026, 7:58 AM EDT
Completed No phase listed Observational

Analysis of Eye Tissue

NCT00001224
View directory record Official record
Conditions
Eye Disease, Inflammation, Uveitis
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1987 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System

NCT03278223
View directory record Official record
Conditions
Myopia, Hyperopia
Interventions
Test solution, Control solution
Device
Lead sponsor
OTE North America
Industry
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
5
States / cities
Sarasota, Florida • Pittsburg, Kansas • Vestal, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2021 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Total30 For Contact Lens Dropouts

NCT06967298
View directory record Official record
Conditions
Dry Eye, Contact Lens Complication, Contact Lenses
Interventions
T30 Contact lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear

NCT01735045
View directory record Official record
Conditions
Myopia
Interventions
Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
Device
Lead sponsor
Szabocsik and Associates, Inc.
Industry
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
5
States / cities
Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Results available

Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL

NCT04210232
View directory record Official record
Conditions
Cataract, Corneal Astigmatism
Interventions
TECNIS® TORIC II Intraocular Lens (IOL)
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
12
States / cities
Bakersfield, California • Sioux City, Iowa • Annapolis, Maryland + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 25, 2026, 7:58 AM EDT
Not listed Not applicable Interventional

Manual Small Incision Cataract Surgery Outcomes in an Educational Setting

NCT02277314
View directory record Official record
Conditions
Cataracts
Interventions
Manual Small Incision Cataract Surgery
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 25, 2026, 7:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Dynamic Light Scattering to Study Crystalline Proteins in Young Normal Lenses

NCT00304967
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
5 Years to 21 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional

Clinical Performance of a Daily Disposable Toric Silicone Hydrogel Contact Lens

NCT04464044
View directory record Official record
Conditions
Astigmatism
Interventions
verofilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional

Technology-based Eye Care Services (TECS) Compare

NCT02558712
View directory record Official record
Conditions
Cataract, Macular Degeneration, Glaucoma
Interventions
Technology-based Eye Care Services (TECS) Protocol
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2018 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Need for the Pseudophakic Intraoperative Abberrometry in Toric IOL Implantation

NCT03819842
View directory record Official record
Conditions
Cataract, Nuclear Sclerosis, Cortical Cataract, Posterior Subcapsular Cataract, Astigmatism
Interventions
Pseudophakic Measurement
Diagnostic Test
Lead sponsor
Alterman, Modi, & Wolter Ophthalmic Physicians & Surgeons
Other
Eligibility
30 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Poughkeepsie, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Oct 25, 2026, 7:58 AM EDT
Completed Not applicable Interventional Results available

A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)

NCT03274986
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 25, 2026, 7:58 AM EDT