Search | Clinical Trials Finder

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Nov 9, 2026, 5:30 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 505–528 of 1,257 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Local Disease Clear all

Conditions: Pain, Postoperative, Hernia, Ventral, Abdominoplasty, Hysterectomy, Colectomy, Reduction Mammoplasty
Interventions: INL-001 (bupivacaine hydrochloride) implant; Combination Product
Lead sponsor: Innocoll; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 8
States / cities: Florence, Alabama • Sheffield, Alabama • Pasadena, California + 3 more

Conditions: Pelvic Organ Prolapse, Vaginal Atrophy
Interventions: Vaginal conjugated estrogen cream 0.5gm, Vaginal conjugated estrogen cream 1.0gm; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 45 Years and older · Female only
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Pain, Procedural
Interventions: Lidocaine; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: Up to 6 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: COPD
Interventions: Perfluorinated Gas/Oxygen Mixture, High Resolution CT of the Chest; Drug · Other
Lead sponsor: Hal C Charles; Other
Eligibility: 18 Years and older
Enrollment: 171 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Pain, Chronic
Interventions: in clinic pain VR reduction exercises, In clinic VRpain reduction exercises + VR homeworks; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 85 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Abscess
Interventions: Lidocaine, Vapocoolant; Drug
Lead sponsor: Albert Einstein Healthcare Network; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Glioblastoma Multiforme
Interventions: temozolomide, Brachytherapy, External Beam Radiation Therapy; Drug · Procedure
Lead sponsor: Methodist Healthcare - Memphis; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2006
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Cancer of Prostate, Cancer of the Prostate, Neoplasms, Prostate, Neoplasms, Prostatic, Prostate Cancer, Prostate Neoplasms, Prostatic Cancer
Interventions: androgen ablation (AA), DC1 vaccine; Biological
Lead sponsor: Roswell Park Cancer Institute; Other
Eligibility: 18 Years and older · Male only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2019
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Vulvar Diseases, Anesthesia, Anesthesia, Local
Interventions: Ice Pre-treatment, Room Temperature Water Pre-treatment; Other
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Anemia of Prematurity, Necrotizing Enterocolitis
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: Up to 12 Weeks
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 3
States / cities: Murray, Utah • Salt Lake City, Utah

Conditions: Gastrointestinal Carcinoid Tumor, Islet Cell Tumor, Neoplastic Syndrome
Interventions: AMG 706, octreotide; Drug
Lead sponsor: Eastern Cooperative Oncology Group; Network
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 112
States / cities: Berwyn, Illinois • Chicago, Illinois • Joliet, Illinois + 78 more

Conditions: Family Relationships, Parent-Child Relationships
Interventions: PREP 8.0 curriculum developed by PREP, Within My Reach curriculum developed by PREP, Within Our Reach 8 Hours curriculum; Other
Lead sponsor: Children's Aid Society in Clearfield County; Other
Eligibility: 18 Years and older
Enrollment: 1,119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Clearfield, Pennsylvania

Conditions: HIV Infections, Hepatitis B, Chronic
Interventions: 1% tenofovir gel; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2007
U.S. locations: 2
States / cities: Birmingham, Alabama • The Bronx, New York

Conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis
Interventions: Methylprednisolone; Drug
Lead sponsor: Stanford University; Other
Eligibility: 4 Years to 25 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Prostate Carcinoma, Stage IIC Prostate Cancer AJCC v8, Stage III Prostate Cancer AJCC v8, Stage IIIA Prostate Cancer AJCC v8, Stage IIIB Prostate Cancer AJCC v8, Stage IIIC Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8
Interventions: Abiraterone Acetate, Antiandrogen Therapy, Apalutamide, Biopsy, Niraparib, Prednisone, Radiation Therapy; Drug · Procedure · Radiation
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Male only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Esophageal Cancer, Adenocarcinoma of the Esophagus, Squamous Cell Carcinoma
Interventions: OncoGel (Paclitaxel gel), cisplatin, 5-FU, radiation therapy, esophageal resection; Drug · Radiation · Procedure
Lead sponsor: Boston Scientific Corporation; Industry
Eligibility: 18 Years and older
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 8
States / cities: San Diego, California • Chicago, Illinois • Indianapolis, Indiana + 4 more

Conditions: Pancreatic Cancer
Interventions: Gemcitabine, local delivery; Drug
Lead sponsor: RenovoRx; Industry
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Mountain View, California • Tampa, Florida

Conditions: Colorectal Cancer, Metastatic Cancer
Interventions: FOLFIRI regimen, floxuridine, fluorouracil, irinotecan hydrochloride, leucovorin calcium, melphalan, hyperthermia treatment; Drug · Procedure
Lead sponsor: National Institutes of Health Clinical Center (CC); NIH
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Dyspareunia
Interventions: 50mcg estradiol cream, 100mcg estradiol cream; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 40 Years to 70 Years · Female only
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hip Pain
Interventions: bacteriostatic saline, buffered lidocaine; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 75 Years
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Brain and Central Nervous System Tumors, Neuroblastoma, Retinoblastoma, Sarcoma
Interventions: filgrastim, carboplatin, cisplatin, cyclophosphamide, etoposide, leucovorin calcium, methotrexate, temozolomide, thiotepa, vincristine sulfate, autologous bone marrow transplantation, peripheral blood stem cell transplantation, radiation therapy; Biological · Drug · Procedure + 1 more
Lead sponsor: NYU Langone Health; Other
Eligibility: Up to 10 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1997
U.S. locations: 17
States / cities: Honolulu, Hawaii • Scarborough, Maine • Grand Rapids, Michigan + 11 more

Conditions: Breast Cancer, Postoperative Pain, Opioid Use, Local Anesthesia
Interventions: Pectoral Nerve Block, Surgery without Nerve Block; Procedure
Lead sponsor: Main Line Health; Other
Eligibility: 18 Years and older · Female only
Enrollment: 130 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pain
Interventions: Sodium bicarbonate, Lidocaine; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 9 Years to 12 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Peri-implantitis
Interventions: Resective surgery with implantoplasty, Resective surgery with mechanical debridement; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

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An Open-label Safety and Pharmacokinetic Study of INL-001 in Adults Following Various Open Soft-Tissue Surgeries

The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse

The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort

Imaging Regional Lung Defect Severity

Using Immersive Virtual Reality to Treat Complex Regional Pain Syndrome in Adults

Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage

Radiation Boost for Newly Diagnosed Glioblastoma Multiforme

Dendritic Cell (DC)-Based Vaccines Loaded With Allogeneic Prostate Cell Lines in Combination With Androgen Ablation in Patients With Prostate Cancer

Treatment Prior to Injection and Biopsy of the Vulva

Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates

AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors

Local Evaluation of Real Relationships

Safety and Acceptability of a Vaginal Microbicide

High Dose Steroid Therapy to Treat Flares in Patients With Inflammatory Bowel Disease (IBD)

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer

A Dose Escalation Safety Study of Locally-Delivered Gemcitabine in Pancreatic Cancer

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Treating Postmenopausal Dyspareunia Where it Hurts

Comparison of Bacteriostatic Saline to Buffered Lidocaine for Ultrasound Guided Hip Joint Injection Local Anesthesia

Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

PECS Block in Partial Mastectomy for Postoperative Pain Control

Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients

Peri-implantitis Management: Surgical and Maintenance Outcomes