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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Loneliness Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Social Activity, Loneliness and Stigma During COVID-19 Outbreak

NCT04734171
View directory record Official record
Conditions
Covid19, Fear, Loneliness
Interventions
Digital social activity video intervention, Informational sheet, Stigma awareness video intervention
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Results available

Technology and Family Thriving Study

NCT05150990
View directory record Official record
Conditions
Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life, Mental Health Wellness 1, Loneliness, Family Relationship
Interventions
Virtual Reality, Video Chat
Behavioral
Lead sponsor
University of California, Santa Barbara
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Calabasas, California • Camarillo, California • Goleta, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Not listed Not applicable Interventional

Virtual Yoga for Social Isolation and Loneliness in Rural Veterans

NCT05431166
View directory record Official record
Conditions
Loneliness, Social Isolation
Interventions
Virtual Yoga at First 8 weeks, Virtual Yoga at Second 8 weeks
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 88 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional

10,000 Step Club: Community Walking Program for People with Parkinson's Disease

NCT06605183
View directory record Official record
Conditions
Parkinson Disease
Interventions
Community walking program using Nordic walking poles
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
30 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Heartfulness Self-Care Program on Anxiety, Satisfaction With Life, and Loneliness Levels in Students and Staff in High Schools.

NCT05874232
View directory record Official record
Conditions
Anxiety, Satisfaction With Life, Loneliness
Interventions
Self-Care Program through Heartfulness
Behavioral
Lead sponsor
Heartfulness Institute
Other
Eligibility
14 Years to 80 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional

Fostering Agricultural Relationships and Meaning - Thriving on Kinship

NCT07218965
View directory record Official record
Conditions
Loneliness, Social Isolation, Rural Health
Interventions
Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BabaCare: Testing a Care Copilot

NCT07689526
View directory record Official record
Conditions
Loneliness, Mood
Interventions
AI phone companion
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sauna for Offline Connections and Interactive, Authentic Living

NCT07223099
View directory record Official record
Conditions
Loneliness
Interventions
Sauna Visits
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
19 Years to 22 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Keep Social Study for Young Adults

NCT07005817
View directory record Official record
Conditions
Social Isolation, Loneliness
Interventions
Experimental Health Communication, Simulated Social Media Platform Only
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 29 Years
Enrollment
1,900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of a Telephone Reminiscence Program

NCT05977608
View directory record Official record
Conditions
Mental Health, Loneliness, Social Isolation
Interventions
Telephone Reminiscence Intervention
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
60 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality Travel to Reduce Loneliness in Older Adults

NCT07644416
View directory record Official record
Conditions
Loneliness, Older Adults (65 Years and Older), Virtual Reality, Leisure Activities
Interventions
Virtual Reality Travel, Puzzle-Based Attention Control Activity
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Bloomington, Indiana • Ellettsville, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The VESPA Pilot Study

NCT04756245
View directory record Official record
Conditions
Exercise, Behavior, Loneliness, Social Isolation
Interventions
Virtual Reality, Video Conference
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
45 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Telephone Calls for Health for Homebound Older Adults

NCT04595708
View directory record Official record
Conditions
Loneliness, Social Isolation, Depression
Interventions
Phone Call
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Results available

Mental Health Among Patients, Providers, and Staff During the COVID-19 Era

NCT04700137
View directory record Official record
Conditions
Covid19, Mental Health
Interventions
Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
Other
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
666 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Compassion Training and Mindfulness Training for Social Well-Being and Mental Health

NCT05227794
View directory record Official record
Conditions
Anxiety, Depression, Stress, Burnout, Emotion Regulation, Social Acceptance, Loneliness, Compassion
Interventions
Compassion Cultivation Training (CCT), Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Jul 21, 2026, 11:33 PM EDT
Not yet recruiting Not applicable Interventional

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial

NCT07223736
View directory record Official record
Conditions
Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health, Depression, Peritraumatic Distress, Women, Artificial Intelligence (AI), Chatbot
Interventions
Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Group-Based Online Virtual Reality Gaming to Improve Mental Health Among Children With Physical Disabilities

NCT05259462
View directory record Official record
Conditions
Disability Physical
Interventions
Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Jul 21, 2026, 11:33 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Commensality Groups: A Professional Fulfillment Intervention for Medical Students in Their Clinical Years

NCT06656650
View directory record Official record
Conditions
Professional Fulfillment, Burnout, Social Isolation or Loneliness
Interventions
Commensality groups
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness

NCT04414826
View directory record Official record
Conditions
Loneliness
Interventions
Mindfulness Alone (MO) Intervention, Mindfulness + Compassion Intervention (MC)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 70 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Loving Kindness Meditation Among Adults 50 Years and Older

NCT05350449
View directory record Official record
Conditions
Loneliness
Interventions
Loving-kindness Meditation
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
50 Years and older
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Recruiting Not applicable Interventional

Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT

NCT06969261
View directory record Official record
Conditions
Perinatal Opioid Use Disorder, Opioid Use Disorder
Interventions
Penny COPILOT
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ecological Momentary Assessment and Text Message Intervention for Stress Management

NCT04907942
View directory record Official record
Conditions
Stress, Psychological, Loneliness, Covid19, Stress
Interventions
EMA + EMA and FACE Stress, EMA Alone
Other
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Loneliness Epidemic Tailoring Interventions to Reduce Loneliness and Pain

NCT05387447
View directory record Official record
Conditions
Pain, Chronic, Loneliness
Interventions
Conversational Voice Assistant (Enhanced), Conversational Voice Assistant (Standard)
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
60 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
4
States / cities
Lincoln, Nebraska • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Jul 21, 2026, 11:33 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effects of Animal Assisted Therapy in Outpatient Psychiatry Clinics

NCT05326074
View directory record Official record
Conditions
Anxiety, Depression, Psychiatric or Mood Diseases or Conditions
Interventions
Animal assisted therapy cohort
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Jul 21, 2026, 11:33 PM EDT