Independent directory Public ClinicalTrials.gov records United States
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Showing 25–48 of 132 matching trials from the live ClinicalTrials.gov search.
Conditions
Social Isolation or Loneliness
Interventions
Talk2gether program
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers

A Smartphone Intervention for Relational and Mental Well Being

NCT04629755
Conditions
Depression, Loneliness, Relation, Interpersonal, Covid19
Interventions
Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,765 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Music Therapy and Social Work Telehealth for Older Adult Well-Being

NCT06219148
Conditions
Aging Well, Dementia, Telemedicine
Interventions
Music Therapy Telehealth, Non-Collaborative Social Work Telehealth, Collaborative Social Work Telehealth
Behavioral
Lead sponsor
Alaine E Hernandez, PhD
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • St Louis, Missouri
Conditions
Mood, Depression Disorders, Anxiety Disorders, Sleep, Eating Disorders, Physical Activity, Loneliness, Stress
Interventions
Not listed
Lead sponsor
Aura
Industry
Eligibility
8 Years to 17 Years
Enrollment
912 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Video Chat During Meals to Improve Nutritional Intake in Older Adults

NCT04862312
Conditions
Malnutrition, Loneliness
Interventions
VideoDine
Behavioral
Lead sponsor
Cornell University
Other
Eligibility
60 Years to 95 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ithaca, New York
Conditions
Stress, Psychological, Depression and/or Anxiety in the Mild-to-moderate Range, Loneliness, Adjustment, Psychological
Interventions
Digitized SH+
Behavioral
Lead sponsor
The New School
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Completed Not applicable Interventional Results available

The Association Between Loneliness and Substance Use

NCT04938492
Conditions
Opioid Use, Loneliness
Interventions
Cognitive Behavioral Therapy for loneliness (CBT-L), Physical Health Education Training (PHET)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Twitter Based Social Support for Hispanic and Black Dementia Caregivers

NCT03865498
Conditions
Loneliness, Emotional Stress
Interventions
Twitter for Hispanic caregivers, Twitter for African American caregivers
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
966 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Stress Management Training for Healthy Aging

NCT02888600
Conditions
Psychological Stress, Loneliness
Interventions
Mindfulness Training, Health Education
Behavioral
Lead sponsor
Carnegie Mellon University
Other
Eligibility
65 Years to 93 Years
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Richmond, Virginia
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Early Phase 1 Interventional Accepts healthy volunteers

Oxytocin and Social Behavior Over the Lifespan

NCT00914953
Conditions
Social Activity
Interventions
oxytocin (Pitocin)
Drug
Lead sponsor
Claremont Graduate University
Other
Eligibility
50 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

How Do Artificially Intelligent Companions Influence Psychological Outcomes?

NCT07858279
Conditions
AI Companionship
Interventions
AI Companion Interaction
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ecological Momentary Assessment and Text Message Intervention for Stress Management

NCT04907942
Conditions
Stress, Psychological, Loneliness, Covid19, Stress
Interventions
EMA + EMA and FACE Stress, EMA Alone
Other
Lead sponsor
Click Therapeutics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Telephone Calls for Health for Homebound Older Adults

NCT04595708
Conditions
Loneliness, Social Isolation, Depression
Interventions
Phone Call
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Austin, Texas
Conditions
Opioid Use Disorder, Loneliness, Social Isolation
Interventions
Cognitive-Behavioral Therapy for Perceived Social Isolation, Health Education
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Rochester, New York
Conditions
Cancer, Cancer Metastatic, Neoplasms, Breast Cancer, Lung Cancer, Glioblastoma, Prostate Cancer, Gynecologic Cancer, Colorectal Cancer, Sarcoma, Kidney Cancer, Bladder Cancer, Lymphoma, Leukemia, Head and Neck Cancer, Pancreas Cancer, Multiple Myeloma, Anxiety, Social Isolation, Stress, Loneliness, Melanoma, Uterine Cancer
Interventions
Elly Mobile Phone Application
Behavioral
Lead sponsor
Gillian Gresham
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors

NCT04913363
Conditions
Loneliness, Social Isolation, Mood, Well Aging, Physical Activity, Mobility Limitation
Interventions
Green space
Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Critical Illness, Social Isolation, Anxiety, Depression, Post Intensive Care Unit Syndrome
Interventions
Social Engagement
Behavioral
Lead sponsor
Kirby Mayer
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Terminated Not applicable Interventional Accepts healthy volunteers

Loneliness and Social Connection in Cardiovascular Disease

NCT04195620
Conditions
Cardiovascular Diseases
Interventions
High self-disclosure, Low self-disclosure
Other
Lead sponsor
Morehead State University
Other
Eligibility
18 Years to 25 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Morehead, Kentucky
Conditions
Loneliness
Interventions
RELOAD-C
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Manhasset, New York • New Hyde Park, New York • New York, New York + 1 more
Recruiting No phase listed Observational Accepts healthy volunteers

Social Disconnection Study

NCT06705348
Conditions
Social Disconnection
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
55 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Parkinson Disease
Interventions
Community walking program using Nordic walking poles
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
30 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality Travel to Reduce Loneliness in Older Adults

NCT07644416
Conditions
Loneliness, Older Adults (65 Years and Older), Virtual Reality, Leisure Activities
Interventions
Virtual Reality Travel, Puzzle-Based Attention Control Activity
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Bloomington, Indiana • Ellettsville, Indiana
Conditions
Depression, Loneliness, Social Isolation, Depressive Disorder, Mood Disorders, Mental Disorder
Interventions
Empower@Home:Connected
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Ann Arbor, Michigan