Clinical Trials Finder
Independent ClinicalTrials.gov directory
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced May 21, 2026, 7:18 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 186 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Lumbar Disc Disease Clear all
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Lumbar Degenerative Disease, Lumbar Degenerative Disc Disease, Degenerative Spine
Interventions
ISOVUE 300 Observation, ISOVUE 300 Feedback
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced May 21, 2026, 7:18 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease (DDD)
Interventions
Lumbar Interbody Fusion Devices
Device
Lead sponsor
Spine and Scoliosis Research Associates
Other
Eligibility
18 Years to 110 Years
Enrollment
465 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
San Francisco, California • New York, New York • Charlotte, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced May 21, 2026, 7:18 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
One-level or two-level anterior lumbar interbody fusion, InQu Bone Graft Extender and Substitute mixed with BMAC, Synthes Spinal Instrumentation
Procedure · Biological · Device
Lead sponsor
Kansas Joint and Spine Institute
Network
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2012 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Delirium, Lumbar Radiculopathy, Lumbar Osteoarthritis, Lumbar Spine Disc Degeneration
Interventions
Light sedation with propofol, Induction with propofol, Maintenance anesthetic using a volatile anesthetic, Muscle relaxant during maintenance anesthesia, Pain control with fentanyl, Bispectral Index (BIS) monitoring for depth of anesthesia, Spinal Anesthesia, Midazolam administered during spinal anesthesia, Cerebrospinal fluid collection, Administration of intrathecal morphine
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced May 21, 2026, 7:18 PM EDT
Terminated Phase 3 Interventional
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Lumbar Transforaminal Epidural Corticosteroid Injection, Physical Therapy, Observation
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 64 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Daly City, California • Mill Valley, California • Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced May 21, 2026, 7:18 PM EDT
Active, not recruiting Phase 3 Interventional
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease
Interventions
SB-01 For Injection, Sham Needle
Drug
Lead sponsor
Spine BioPharma, Inc
Industry
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
30
States / cities
Birmingham, Alabama • Phoenix, Arizona • Napa, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2025 · Synced May 21, 2026, 7:18 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Disc Herniation
Interventions
Two-Week Post-Operative Restriction, Six-Week Post-Operative Restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
HEALOS and Leopard Cage, Leopard Cage and Autograft
Device
Lead sponsor
Advanced Technologies and Regenerative Medicine, LLC (ATRM)
Other
Eligibility
18 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
17
States / cities
Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2011 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Intervertebral Disc Disease, Lumbar Disc Disease
Interventions
Condoliase, placebo
Drug
Lead sponsor
Seikagaku Corporation
Industry
Eligibility
30 Years to 70 Years
Enrollment
385 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
32
States / cities
Phoenix, Arizona • Gold River, California • Laguna Hills, California + 29 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Lumbar Osteoarthritis, Spondylosis, Lumbar Disc Disease, Spinal Stenosis
Interventions
Ketorolac, Acetaminophen, Placebo
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced May 21, 2026, 7:18 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Intervertebral Disc Disorders With Radiculopathy, Lumbar Region
Interventions
Ensure
Dietary Supplement
Lead sponsor
NYU Langone Health
Other
Eligibility
55 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced May 21, 2026, 7:18 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
Interventions
MagnetOs Flex Matrix, Trinity Elite
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Hartford, Connecticut • Columbia, Maryland • Bloomfield Hills, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced May 21, 2026, 7:18 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
Interventions
ALIF
Device
Lead sponsor
Camber Spine Technologies
Industry
Eligibility
22 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
Interventions
PLF with autograft, PLF with NeoFuse
Procedure · Biological
Lead sponsor
Mesoblast, Ltd.
Industry
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2020 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 3 Interventional
View directory record Official record
Conditions
Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
Interventions
Morphine, Epinephrine, naropin
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Disc Degeneration
Interventions
MSC Treatment group 1 (low dose), MSC Treatment group 2 (high dose), Healthy Control (no treatment)
Drug · Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced May 21, 2026, 7:18 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Degeneration, Spinal Stenosis
Interventions
Computed Tomography (CT) Scan of the Lumbar Spine
Radiation
Lead sponsor
Bone and Joint Clinic of Baton Rouge
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 3 Interventional
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
rhBMP-2/CRM/CD HORIZON® Spinal System, Autograft/CD HORIZON® Spinal System
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
18 Years and older
Enrollment
463 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2010
U.S. locations
28
States / cities
Phoenix, Arizona • Orange, California • Santa Monica, California + 25 more
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
IDCT, Saline Solution, Sodium Hyaluronate
Biological · Drug
Lead sponsor
DiscGenics, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced May 21, 2026, 7:18 PM EDT
Withdrawn Phase 2 Interventional
View directory record Official record
Conditions
Degeneration Disc Intervertebral
Interventions
Abaloparatide, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 11, 2021 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Intervertebral Disc Disease, Lumbar Disc Disease
Interventions
Condoliase
Drug
Lead sponsor
Seikagaku Corporation
Industry
Eligibility
30 Years to 70 Years
Enrollment
1,011 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
30
States / cities
Mobile, Alabama • Phoenix, Arizona • Gold River, California + 27 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced May 21, 2026, 7:18 PM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Baxano Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
11
States / cities
Fullerton, California • Los Angeles, California • Carmel, Indiana + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2014 · Synced May 21, 2026, 7:18 PM EDT
Completed Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5
Drug
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
8
States / cities
Santa Monica, California • Durango, Colorado • Marietta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced May 21, 2026, 7:18 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
Interventions
Water
Other
Lead sponsor
Milwaukee VA Medical Center
Federal
Eligibility
20 Years to 45 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced May 21, 2026, 7:18 PM EDT