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ClinicalTrials.gov public records Last synced May 21, 2026, 11:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Lumbar Disc Disease Clear all
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
Interventions
Interbody cage (titanium), Interbody cage (PEEK)
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 14, 2023 · Synced May 21, 2026, 11:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions
Multimodal Analgesia, Patient controlled analgesia
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced May 21, 2026, 11:10 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
MagnetOs Flex Matrix
Device
Lead sponsor
Research Source
Network
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced May 21, 2026, 11:10 PM EDT
Terminated Phase 2 Interventional
View directory record Official record
Conditions
Lumbar Degenerative Disc Disease
Interventions
PDS System, Fusion
Device
Lead sponsor
Interventional Spine, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Cincinnati, Ohio • Willow Grove, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2013 · Synced May 21, 2026, 11:10 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Lumbago, Lumbar Spinal Stenosis, Lumbar Disc Herniation
Interventions
Post Epidural Steroid Injection Follow-up
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Timeline
2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced May 21, 2026, 11:10 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Spondylolisthesis, Scoliosis, Intervertebral Disc Disease
Interventions
OsteoAMP
Other
Lead sponsor
Bioventus LLC
Industry
Eligibility
21 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
9
States / cities
New Haven, Connecticut • Chicago, Illinois • Kansas City, Kansas + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced May 21, 2026, 11:10 PM EDT
Enrolling by invitation No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Scoliosis, Spinal Stenosis, Sagittal Deformity
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
16
States / cities
La Jolla, California • Los Alamitos, California • Merced, California + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced May 21, 2026, 11:10 PM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Grade 1, Retrolisthesis
Interventions
AccuLIF expandable TLIF cage
Device
Lead sponsor
Stryker Spine
Industry
Eligibility
18 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced May 21, 2026, 11:10 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Intervertebral Disc Disease, Intervertebral Disc Degeneration, Spondylosis, Spondylolisthesis, Spinal Stenosis
Interventions
NuCel with Autograft
Other
Lead sponsor
NuTech Medical, Inc
Industry
Eligibility
21 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced May 21, 2026, 11:10 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Scarring, Spinal Stenosis, Herniated Disc
Interventions
Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced May 21, 2026, 11:10 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease Lumbar, Spondylolisthesis, Grade 1
Interventions
Device: EVOS Lumbar Interbody System (EVOS-HA)
Device
Lead sponsor
Invibio Ltd
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced May 21, 2026, 11:10 PM EDT
Recruiting Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Lumbar Disc Disease, Spine Disease, Lumbar Spine Degeneration
Interventions
LDGraft, Allograft Bone
Device · Other
Lead sponsor
Locate Bio Pty Ltd
Industry
Eligibility
22 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced May 21, 2026, 11:10 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Interlaminar Epidural, Lumbar Interlaminar Epidural injection
Procedure
Lead sponsor
Pain Management Center of Paducah
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced May 21, 2026, 11:10 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain
Interventions
VIA Disc NP, Sham
Other
Lead sponsor
VIVEX Biologics, Inc.
Industry
Eligibility
22 Years to 85 Years
Enrollment
496 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
19
States / cities
Napa, California • Santa Monica, California • Thornton, Colorado + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced May 21, 2026, 11:10 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal, Intervertebral Disc Injury
Interventions
NSSD, Sham NSSD
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Stanford, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced May 21, 2026, 11:10 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Orange, California • Jacksonville, Florida • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced May 21, 2026, 11:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Active Allograft, Placebo
Other
Lead sponsor
VIVEX Biologics, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
13
States / cities
Santa Monica, California • Walnut Creek, California • Tampa, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced May 21, 2026, 11:10 PM EDT
Completed Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Lumbar Disc Herniation
Interventions
KTP-001
Drug
Lead sponsor
Teijin America, Inc.
Industry
Eligibility
30 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
10
States / cities
Birmingham, Alabama • Phoenix, Arizona • Encinitas, California + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced May 21, 2026, 11:10 PM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Lumbar Disc Herniation
Interventions
Dexamethasone, saline 0.9%
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced May 21, 2026, 11:10 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Disc Disease
Interventions
ExcelsiusGPS™
Procedure
Lead sponsor
Globus Medical Inc
Industry
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced May 21, 2026, 11:10 PM EDT
Withdrawn Phase 2 Interventional
View directory record Official record
Conditions
Lumbar Disc Disease, Spinal Fusion, Degenerative Disc Disease
Interventions
Propranolol Hcl 40mg Tab, Placebo oral tablet
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced May 21, 2026, 11:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Type 2 Diabetes, Neuropathy, Painful, Chronic Low-back Pain, Lumbar Disc Herniation
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
45 Years to 75 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced May 21, 2026, 11:10 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
Interventions
OSTEOAMP, Infuse
Other · Device
Lead sponsor
Bioventus LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
9
States / cities
New Haven, Connecticut • Wichita, Kansas • Paducah, Kentucky + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2023 · Synced May 21, 2026, 11:10 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions
Not listed
Lead sponsor
Baxano Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Fullerton, California • Waterford, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2014 · Synced May 21, 2026, 11:10 PM EDT