Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 17, 2026, 8:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Lumbar Puncture Clear all
Enrolling by invitation Not applicable Interventional

Ultrasound-assisted vs Palpation-guided Lumbar Punctures

NCT07824284
View directory record Official record
Conditions
Lumbar Puncture
Interventions
Ultrasound-Assisted Lumbar Puncture, Standard Palpation-Guided Lumbar Puncture
Procedure · Other
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Camden, New Jersey • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Sep 17, 2026, 8:56 AM EDT
Terminated No phase listed Observational

Prevalence of Pathogens in Cerebrospinal Fluid Obtained From Emergency Department Patients

NCT02207647
View directory record Official record
Conditions
Meningoencephalitis, Other Syndromes Requiring Lumbar Puncture in Emergency Department
Interventions
no intervention
Other
Lead sponsor
Olive View-UCLA Education & Research Institute
Other
Eligibility
3 Months and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Sep 17, 2026, 8:56 AM EDT
Terminated Not applicable Interventional

Ultrasound Guided Diagnostic Lumbar Puncture in Neurology

NCT03815045
View directory record Official record
Conditions
Lumbar Puncture
Interventions
Landmark-based lumbar puncture, Ultrasound-guided lumbar puncture
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Incidence of Headache Following an Unintentional Dural Puncture

NCT01977898
View directory record Official record
Conditions
Postdural Puncture Headache, Post-Lumbar Puncture Headache, Cerebrospinal Fluid Leaks
Interventions
Morphine, Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

Lumbar Puncture and Syphilis Outcome

NCT02031146
View directory record Official record
Conditions
Syphilis
Interventions
Lumbar puncture
Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 24, 2021 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound vs Palpation for Infant Lumbar Puncture

NCT02373774
View directory record Official record
Conditions
Spinal; Puncture, Complications
Interventions
Ultrasound
Device
Lead sponsor
Columbia University
Other
Eligibility
Up to 90 Days
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional Results available

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

NCT04796935
View directory record Official record
Conditions
Central Nervous System Infections, Pseudotumor Cerebri, Neurological Disorder, Cancer, Obstetric Procedure Pain, Orthopedic Procedure Pain, Post-Dural Puncture Headache
Interventions
Tactile Imaging (VerTouch), Control (palpation)
Device · Other
Lead sponsor
IntuiTap Medical, Inc
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
3
States / cities
Providence, Rhode Island • Charleston, South Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Sep 17, 2026, 8:56 AM EDT
Not listed No phase listed Observational

Validation of Non-Invasive Intracranial Pressure (ICP) Monitoring Device

NCT03865576
View directory record Official record
Conditions
Intracranial Hypertension, Abnormality of Intracranial Pressure
Interventions
Non-invasive ICP measurement
Diagnostic Test
Lead sponsor
Boston Neurosciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
4
States / cities
Phoenix, Arizona • Atlanta, Georgia • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 17, 2026, 8:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Early Diagnosis of Candidiasis in Premature Infants

NCT00109525
View directory record Official record
Conditions
Infection, Candida, Candidiasis, Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
Interventions
Not listed
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
3 Days to 120 Days
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
20
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Sep 17, 2026, 8:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Herpes Virus-6 and Epilepsy

NCT00085683
View directory record Official record
Conditions
Epilepsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 17, 2026, 8:56 AM EDT
Active, not recruiting Not applicable Interventional

Video-Assisted Informed Consent for Neonatal Lumbar Puncture

NCT07074925
View directory record Official record
Conditions
Lumbar Puncture, Pediatrics, Emergency Department Patient, Informed Consent
Interventions
Video assisted informed consent, Standard consent
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
0 Months to 7 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 17, 2026, 8:56 AM EDT
Not yet recruiting Not applicable Interventional

Needle-Free Lidocaine Injection vs Traditional Local Anesthesia in Infant Lumbar Puncture

NCT06552351
View directory record Official record
Conditions
Anesthesia
Interventions
Needle-Free Jet Injection of 1 % lidocaine, traditional needle infiltration of 1% lidocaine
Device · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Day to 3 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Propofol Versus Propofol-Fentanyl as Sedation For Lumbar Puncture in Children With Acute Leukemia/Lymphoma

NCT00214370
View directory record Official record
Conditions
Leukemia, Lymphoma
Interventions
Propofol-Fentanyl, Propofol alone
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 4, 2015 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Phase 4 Interventional Results available

A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department

NCT03085563
View directory record Official record
Conditions
Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
2 Years to 17 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Patient Outcomes in Simulation Education (POISE) Intravenous (IV) and Lumbar Puncture (LP) Multi-institution Protocol

NCT01548547
View directory record Official record
Conditions
Infant Lumbar Puncture
Interventions
Simulation-based mastery learning
Other
Lead sponsor
Columbia University
Other
Eligibility
24 Years to 40 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 17, 2026, 8:56 AM EDT
Not yet recruiting Not applicable Interventional

Lumbar Punctures for the Detection of ctDNA in the Cerebrospinal Fluid of Patients With Stage III and IV Non-Small Cell Lung Cancer

NCT06816979
View directory record Official record
Conditions
Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8
Interventions
Biospecimen Collection, Lumbar Puncture, Magnetic Resonance Imaging
Procedure · Device
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Phase 4 Interventional Results available

"Lidocaine 4% Cream (LMX4) vs Placebo for Pain Due to Lumbar Puncture in Infants 0-60 Days of Age."

NCT00533468
View directory record Official record
Conditions
Pain
Interventions
Lidocaine Cream 4%, Placebo
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
0 Days to 60 Days
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Sep 17, 2026, 8:56 AM EDT
Completed No phase listed Observational Results available

Collection and Study of Cerebrospinal Fluid in Patients With Hunter Syndrome

NCT01449240
View directory record Official record
Conditions
Hunter Syndrome
Interventions
No treatment
Other
Lead sponsor
Shire
Industry
Eligibility
Up to 70 Years · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
5
States / cities
Decatur, Georgia • Chicago, Illinois • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Sep 17, 2026, 8:56 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Utility of Ultrasound-Guided Site Marking in Pediatric Lumbar Punctures

NCT04828746
View directory record Official record
Conditions
Ultrasound Therapy; Complications
Interventions
Ultrasound Guided Skin Marking
Procedure
Lead sponsor
Carilion Clinic
Other
Eligibility
Up to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Virtual Reality as a Distraction Technique for Performing Lumbar Punctures in Children and Young Adu

NCT04092803
View directory record Official record
Conditions
Leukemia
Interventions
Virtual Reality
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 25 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Phase 4 Interventional Results available

Pain Control in Pediatric Oncology: Utility of EMLA Cream vs Lidocaine Injection in Lumbar Punctures

NCT04003012
View directory record Official record
Conditions
Leukemia-Lymphoma
Interventions
EMLA, Lidocaine
Drug
Lead sponsor
CAMC Health System
Other
Eligibility
3 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2023 · Synced Sep 17, 2026, 8:56 AM EDT
Withdrawn Phase 4 Interventional

Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics

NCT03181464
View directory record Official record
Conditions
Postdural Puncture Headache, Cerebrospinal Fluid Leak, Spinal; Puncture, Complications, Headache
Interventions
Lidocaine 4%, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Sep 17, 2026, 8:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain

NCT01606150
View directory record Official record
Conditions
Meningitis
Interventions
1% lidocaine, topical lidocaine
Drug
Lead sponsor
Georgetown University
Other
Eligibility
Up to 8 Days
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Sep 17, 2026, 8:56 AM EDT
Completed Not applicable Interventional

Intravenous Fluid Administration's Effect on Pediatric Lumbar Puncture

NCT05302765
View directory record Official record
Conditions
Pediatric Lumbar Puncture
Interventions
Normal Saline Intravenous Fluids
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
0 Months to 3 Months
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 17, 2026, 8:56 AM EDT