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ClinicalTrials.gov public records Last synced Sep 23, 2026, 4:20 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Lung Cancer Screening Clear all
Active, not recruiting Not applicable Interventional Results available

Screening for Ovarian Cancer in Older Patients (PLCO Screening Trial)

NCT01696994
View directory record Official record
Conditions
Ovarian Carcinoma, Ovarian Germ Cell Tumor
Interventions
Laboratory Biomarker Analysis, Screening Questionnaire Administration, Ultrasound Imaging
Other · Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
55 Years to 74 Years · Female only
Enrollment
78,216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening

NCT06389981
View directory record Official record
Conditions
Lung Cancer
Interventions
Veterans peer connect Program
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)

NCT03611881
View directory record Official record
Conditions
Smoking, Tobacco
Interventions
Counseling, Nicotine patch, Community Resource
Behavioral · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
642 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
6
States / cities
Boston, Massachusetts • Newton, Massachusetts • Oak Bluffs, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional Results available

Tele-Navigation of Lung Cancer Screening (Tele-Navi LCS)

NCT05021133
View directory record Official record
Conditions
Lung Cancer
Interventions
Tele-Navi LCS
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
50 Years to 77 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

SPARC - Screening for Lung Cancer With Platelets Via an AI-enabled RNA-based Classifier

NCT07460440
View directory record Official record
Conditions
Lung Cancer, Lung Nodule
Interventions
Platelet RNA-based assay
Diagnostic Test
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

CPRIT: Patient Adherence to Lung Cancer Screening

NCT06872723
View directory record Official record
Conditions
Lung Cancer Screening
Interventions
Lung Cancer Screening
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
340 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Completed No phase listed Observational

Improving Lung Cancer Screening Adherence by Overcoming Barriers for Vulnerable Populations

NCT04969341
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Survey Administration, Electronic Health Record Review
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
Not listed
Enrollment
947 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Educating Smokers About Lung Cancer Screening Using Tobacco Quitlines

NCT04595422
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Educational Intervention, Questionnaire Administration, Survey Administration
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Maine Lung Cancer Coalition: Using CHWs for the Annual Lung Cancer Screening Reminder

NCT04007458
View directory record Official record
Conditions
Lung Cancer
Interventions
Letter, Community Health Worker Phone Call
Behavioral
Lead sponsor
Anne Conners
Other
Eligibility
55 Years to 80 Years
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Augusta, Maine
Source: ClinicalTrials.gov public record
Updated Nov 29, 2020 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Support and Outreach to Increase Screening for Lung Cancer in Patients With a History of Smoking

NCT05679349
View directory record Official record
Conditions
Lung Carcinoma, Tobacco-Related Carcinoma
Interventions
Survey Administration, Educational Activity, Electronic Health Record Review, Counseling
Other
Lead sponsor
Ronald Myers
Other
Eligibility
50 Years to 77 Years
Enrollment
822 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Impact of CONNECT in a Multilingual Population

NCT07111936
View directory record Official record
Conditions
Smoking Cessation, Smoking Cessation Counseling Ability and Practice, Smoking Cessation Counselling, Lung Cancer Screening
Interventions
CONNECT Intervention for multilingual populations, Saliva Sample, Interview
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 80 Years
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Improving Implementation of Lung Cancer Screening in Diverse Populations II

NCT05265897
View directory record Official record
Conditions
Early Detection of Cancer, Lung Cancer
Interventions
CAQ
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EQUAL: EGFR ctDNA QUantative Assessment for Lung Cancer Screening in Asian and Latinx Populations

NCT06716580
View directory record Official record
Conditions
Lung Cancer, EGFR Gene Mutation
Interventions
Circulating Tumor DNA (ctDNA) Assay
Device
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
40 Years to 80 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
6
States / cities
Boston, Massachusetts • Brighton, Massachusetts • Methuen, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The INSPIRE-Lung Study

NCT05824273
View directory record Official record
Conditions
Lung Cancer
Interventions
LungTalk, Non-tailored intervention - Standard of practice
Behavioral
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
50 Years to 80 Years
Enrollment
512 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Nutley, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Evaluation of a Patient 'nudge' on Engagement in Lung Cancer Screening

NCT06474611
View directory record Official record
Conditions
Lung Cancer
Interventions
Patient nudge
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
50 Years to 80 Years
Enrollment
894 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Lung Cancer Biomarkers and Screening

NCT00301119
View directory record Official record
Conditions
Lung Cancer
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
3,606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Awareness, Information, and Resources for Lung Cancer Screening Program for Community-Partnered Lung Cancer Screening

NCT04635761
View directory record Official record
Conditions
Lung Carcinoma
Interventions
Educational Intervention, Questionnaire Administration
Behavioral
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional

Lung Screening Study

NCT00006382
View directory record Official record
Conditions
Lung Cancer
Interventions
bronchoscopic and lung imaging studies, comparison of screening methods, computed tomography, radiography, study of high risk factors
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
55 Years to 74 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
6
States / cities
Birmingham, Alabama • Washington D.C., District of Columbia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated May 4, 2015 · Synced Sep 23, 2026, 4:20 AM EDT
Not yet recruiting No phase listed Observational

Multiparametric Lung MRI With Diffusion-Weighted Imaging in Lung-RADS 4 Lesion Characterization

NCT07768046
View directory record Official record
Conditions
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules, Lung Neoplasms, Lung Cancer Screening
Interventions
Multiparametric chest MRI with diffusion-weighted imaging
Diagnostic Test
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional

CHAMP Lung Cancer Screening Program

NCT07572773
View directory record Official record
Conditions
Lung Cancer, Early Lung Cancer Detection
Interventions
DELFI Diagnostics FirstLook Lung Cancer Screening Blood Test, Low-Does CT Scan
Diagnostic Test
Lead sponsor
Jill Kolesar
Other
Eligibility
50 Years to 77 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Iowa City, Iowa • Waterloo, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 23, 2026, 4:20 AM EDT
Recruiting Not applicable Interventional

Lung Cancer Screening of Family Members of Patients With Mutation-Driven Lung Cancer

NCT07062172
View directory record Official record
Conditions
Lung Cancer, Driver Mutation
Interventions
Low Dose CT Scan
Diagnostic Test
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 80 Years
Enrollment
1,753 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digitally Enhanced Smoking Cessation for High Risk Smokers

NCT04691297
View directory record Official record
Conditions
Smoking, Smoking Cessation, Lung Cancer Screening, Smoking, Tobacco, Smoking Behaviors
Interventions
Escape, Standard Care
Other
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
55 Years to 77 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 23, 2026, 4:20 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Lung EpiCheck Biomarkers Development Study

NCT06245876
View directory record Official record
Conditions
Lung Cancer
Interventions
Blood collection
Other
Lead sponsor
Nucleix Ltd.
Industry
Eligibility
20 Years to 80 Years
Enrollment
6,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
6
States / cities
Miami, Florida • Panama City, Florida • Shreveport, Louisiana + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2024 · Synced Sep 23, 2026, 4:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Incidental Findings Information on Lung Cancer Screening Intent

NCT04432753
View directory record Official record
Conditions
Neoplasm of Lung, Decision Support Techniques, Mass Screening
Interventions
Lung Cancer Screening Decision Aid with Incidental Findings Information, Lung Cancer Screening Decision Aid without Incidental Findings Information
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
55 Years to 80 Years
Enrollment
419 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 9, 2020 · Synced Sep 23, 2026, 4:20 AM EDT