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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Maternal Depression Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Maternal Mental Health in the Hospital Setting

NCT03777046
View directory record Official record
Conditions
Post Partum Depression
Interventions
Standard of Care (SOC), SOC with Psychology Therapy (CBT)
Behavioral
Lead sponsor
Michelle Lopez
Other
Eligibility
18 Years and older · Female only
Enrollment
545 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

New Mothers Alpha-Stim

NCT04770181
View directory record Official record
Conditions
Anxiety, Depression, Insomnia, Sleep Quality
Interventions
Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator)
Device
Lead sponsor
Christina Murphey, RN, PhD
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Trial of CenteringPregnancy With Mindfulness Skills

NCT01646463
View directory record Official record
Conditions
Premature Birth, Low Birth Weight, Postpartum Depression
Interventions
CenteringPregnancy, CenteringPregnancy with Mindfulness Skills
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 16, 2020 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Family Nurture Intervention in the NICU at The Valley Hospital

NCT03267043
View directory record Official record
Conditions
Premature Birth, Obstetric Labor, Premature
Interventions
Family Nurture Intervention (FNI), Standard Care
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
26 Weeks to 34 Weeks
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Ridgewood, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Mommy-Baby Treatment for Perinatal Depression

NCT01744041
View directory record Official record
Conditions
Depressive Disorder, Major, Postpartum Depression
Interventions
Dyadic Interpersonal Psychotherapy, Enhanced Treatment as Usual
Behavioral · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Phase 2 Interventional

Reducing Symptoms of Depression in Low-Income Mothers

NCT00074789
View directory record Official record
Conditions
Depression
Interventions
Modified Interpersonal Therapy, Attention control/usual care
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years and older · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
6
States / cities
Syracuse, New York • Asheville, North Carolina • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Jul 21, 2026, 2:19 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Co-Designing and Evaluating Additional Mothers and Babies Program Content for Expectant and New Parents of Children With Down Syndrome

NCT07469176
View directory record Official record
Conditions
Depression
Interventions
Mothers and Babies, Mothers and Babies Down Syndrome
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Online Yoga With Facebook After Stillbirth

NCT04077476
View directory record Official record
Conditions
Stillbirth, Post-traumatic Stress Disorder, Anxiety, Depression
Interventions
Online Yoga + Facebook, Online Yoga
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Intervention for IPV-exposed Pregnant Women

NCT04068662
View directory record Official record
Conditions
Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence, Parenting
Interventions
Pregnant Moms' Empowerment Program, Nondirective Support Group
Behavioral
Lead sponsor
University of Notre Dame
Other
Eligibility
3 Months to 55 Years · Female only
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Notre Dame, Indiana • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Feasibility Trial of an Online Course (eMB) to Reduce Anxiety and Depression for Pregnant Women and Their Partners

NCT05867680
View directory record Official record
Conditions
Anxiety Disorders Generalized, Depression
Interventions
Online Mothers and Babies Course (eMB)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Postpartum Video Education

NCT05159726
View directory record Official record
Conditions
Postpartum Hemorrhage, Postpartum Preeclampsia, Postpartum Sepsis, Postpartum Depression, Patient Empowerment, Patient Education, Postpartum Care
Interventions
Video Education
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of a Novel Digital Intervention to Prevent Paternal Postpartum Depression

NCT07594743
View directory record Official record
Conditions
Paternal Postpartum Depression, Postpartum Anxiety
Interventions
Together in Parenting
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness and Meditation Based Lactation Education on Maternal Breastmilk in the Neonatal ICU

NCT07351799
View directory record Official record
Conditions
Lactation, Mindfulness, NICU, Breastmilk, Neonatal, Meditation, Pumping, Breast, Cortisol, Oxytocin, Anxiety, Depression
Interventions
Standard of Care, Mindfulness-based Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Phase 2 Interventional

Intervention for Depressed Latina Mothers of Children With Asthma

NCT01326182
View directory record Official record
Conditions
Pediatric Asthma, Maternal Depression
Interventions
MAADRE, MAAS
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Postpartum Video Education in High Risk Populations

NCT06310720
View directory record Official record
Conditions
Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia, Patient Empowerment, Patient Education, Postpartum Care
Interventions
Video Education
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Preterm Outcomes by Safeguarding Maternal Mental Health

NCT01892982
View directory record Official record
Conditions
Depression, Child Development
Interventions
Problem Solving Education tailored to NICU
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Up to 64 Years
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
4
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2018 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Depressed Mothers in Rural Areas: Web-Facilitated Cognitive Behavioral Treatment

NCT01535352
View directory record Official record
Conditions
Maternal Care Patterns
Interventions
Mom-Net, Coach-facilitated Treatment as Usual
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
Female only
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication

NCT06053515
View directory record Official record
Conditions
Pregnancy, Postpartum Depression, Infant Development, Infant Conditions
Interventions
Rosie the Chatbot
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
14 Years to 99 Years · Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Authentic Connections for Nurse Leaders

NCT03616756
View directory record Official record
Conditions
Stress
Interventions
Authentic Connections, Protected time
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Improving Outcomes for Low-Income Mothers With Depression

NCT03221556
View directory record Official record
Conditions
Post Partum Depression
Interventions
Engagement-Focused Care Coordination (EFCC), Problem Solving Education (PSE)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
231 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Perinatal Depression

NCT06525922
View directory record Official record
Conditions
Perinatal Depression
Interventions
Center M
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

NCT06175104
View directory record Official record
Conditions
Heart Defects, Congenital, Anxiety in Pregnancy, Depression, Postpartum, Trauma, Psychological, Neurodevelopmental Disorders
Interventions
HeartGPS
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fresh RX: NHS 2020

NCT04845230
View directory record Official record
Conditions
Premature Birth, Birth Weight, Post Partum Depression, Health Care Utilization, Nutrition Deficiency Due to Insufficient Food, Housing Problems, Fetal Complications, Food Deprivation
Interventions
FreshRx Nourishing Healthy Starts
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 55 Years · Female only
Enrollment
750 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants

NCT03836430
View directory record Official record
Conditions
Postpartum Depression, Preterm Infant, Infant Development
Interventions
Newborn Behavioral Observation-Family Wellness (NBO-FW)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 16, 2022 · Synced Jul 21, 2026, 2:19 PM EDT