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ClinicalTrials.gov public records Last synced Sep 11, 2026, 2:09 AM EDT

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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mechanical Thrombectomy Clear all
Completed Phase 3 Interventional Results available

Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis

NCT00790335
View directory record Official record
Conditions
Deep Vein Thrombosis, Venous Thrombosis, Postphlebitic Syndrome, Venous Thromboembolism, Post Thrombotic Syndrome
Interventions
Recombinant tissue plasminogen activator (rt-PA)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
16 Years to 75 Years
Enrollment
692 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
56
States / cities
Glendale, Arizona • Orange, California • Stanford, California + 48 more
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional

The Pivotal Study of RapidPulseTM Aspiration System

NCT06029491
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
RapidPulseTM Aspiration System
Device
Lead sponsor
RapidPulse, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
18
States / cities
Torrance, California • New Haven, Connecticut • Jacksonville, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Results available

Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3

NCT02586415
View directory record Official record
Conditions
Stroke, Acute, Cerebral Infarction
Interventions
Endovascular Thrombectomy, Trevo Retriever, Solitaire™ FR Revascularization Device, Penumbra thrombectomy system, Covidien MindFrame Capture Revascularization Device
Procedure · Device
Lead sponsor
Gregory W Albers
Other
Eligibility
18 Years to 90 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
40
States / cities
Birmingham, Alabama • Fresno, California • La Jolla, California + 26 more
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational

CERENOVUS Neurothrombectomy Devices Registry

NCT03685578
View directory record Official record
Conditions
Cerebral Stroke
Interventions
EmboTrap® Revascularization Device, CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter, CEREGLIDE 71 Intermediate Catheter
Device
Lead sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
30
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Phase 2Phase 3 Interventional

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy (ALLY) II Trial

NCT06949228
View directory record Official record
Conditions
Ischemic Stroke, Acute Disease
Interventions
tenecteplase
Drug
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Results available

Randomized Trial Evaluating Performance of the Trevo Retriever Versus the Merci Retriever in Acute Ischemic Stroke

NCT01270867
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Mechanical Thrombectomy
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years to 85 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 2, 2015 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Phase 2 Interventional Results available

Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial

NCT05172934
View directory record Official record
Conditions
Ischemic Stroke
Interventions
intra-arterial tenecteplase
Drug
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Phase 3 Interventional

Clevidipine Infusion for Blood Pressure Management After Successful Revascularization in Acute Ischemic Stroke

NCT05175547
View directory record Official record
Conditions
Stroke, Acute, Blood Pressure, Mechanical Thrombectomy
Interventions
Clevidipine
Drug
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Phase 2 Interventional

Safety and Efficacy of J147 in Acute Ischemic Stroke

NCT07430917
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
J147 Emulsion for Injection, Placebo
Drug · Other
Lead sponsor
Abrexa Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
5
States / cities
Long Beach, California • Rockford, Illinois • Albany, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting No phase listed Observational

Cleaner Long-tErm Assessment Registry - Venous Insights and Efficacy With eXtended Tracking

NCT07102160
View directory record Official record
Conditions
Deep Vein Thrombosis (DVT), Thrombus in the Peripheral Venous Vasculature, Venous Embolism, Thrombus in the Central and Peripheral Circulatory System, Including Saphenous Vein Grafts
Interventions
Aspiration thrombectomy system
Device
Lead sponsor
Argon Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
Fort Lauderdale, Florida • Tampa, Florida • Edgewood, Kentucky + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational Results available

ASSIST Registry Studying Various Operator Techniques

NCT03845491
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Mechanical Thrombectomy
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years and older
Enrollment
1,492 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
38
States / cities
Mesa, Arizona • Fontana, California • Los Angeles, California + 34 more
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Results available

Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia

NCT00869375
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Endovascular peripheral intervention
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 85 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 11, 2026, 2:09 AM EDT
Terminated Phase 1 Interventional

Mechanical Thrombectomy Blood Flow Reversal

NCT06721338
View directory record Official record
Conditions
Stroke, Large Vessel Occlusion
Interventions
Mechanical thrombectomy via blood flow reversal using BOBBY balloon guide catheter
Device
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Jamaica, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Terminated No phase listed Observational

LOTUS: Global Acute Stroke Study Utilizing Penumbra System

NCT04157270
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Penumbra System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Englewood, Colorado • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Phase 1 Interventional

Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

NCT05871606
View directory record Official record
Conditions
Cerebrovascular Disorders, Acute Cerebrovascular Disease
Interventions
iNO
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Endovascular Stroke Treatment Only (ESTO) Trial

NCT04240470
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Thrombectomy
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 90 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational

Merci Registry - Real World Use of the Merci Retrieval System in Acute Ischemic Stroke

NCT00478478
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Mechanical Thrombectomy
Procedure
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2014 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational Results available

Trevo® Retriever Registry Post Market Surveillance

NCT02040259
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Not listed
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
Not listed
Enrollment
2,008 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
47
States / cities
Mesa, Arizona • Phoenix, Arizona • Castro Valley, California + 40 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational

COMPLETE: International Acute Ischemic Stroke Registry With the Penumbra System Aspiration Including the 3D Revascularization Device

NCT03464565
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Penumbra System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
29
States / cities
Mesa, Arizona • Castro Valley, California • Fullerton, California + 25 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational

Registry of Emergent Large VeSsel OCclUsion DuE to IntraCranial AtherosclerosiS

NCT05403593
View directory record Official record
Conditions
Intracranial Stenosis, Large Vessel Occlusion, Mechanical Thrombectomy
Interventions
No Intervention
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
14
States / cities
New Haven, Connecticut • Miami, Florida • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional

Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke

NCT07001267
View directory record Official record
Conditions
Acute Ischemic Stroke Patients
Interventions
Anesthesia drugs during the surgery
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Withdrawn Phase 1 Interventional

Intra-Arterial Neuroprotective Agents and Cold Saline in Ischemic Stroke Intervention

NCT05032781
View directory record Official record
Conditions
Stroke, Ischemic
Interventions
Intra-arterial cold saline, minocycline, and magnesium
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Clinical Trial to Evaluate the Safety of Continuous IV Tirofiban in Acute Ischemic Stroke

NCT04818944
View directory record Official record
Conditions
Acute Ischemic Stroke, Ischemic Stroke
Interventions
Tirofiban Hydrochloride, Placebo
Drug
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Sep 11, 2026, 2:09 AM EDT
Terminated Not applicable Interventional Results available

Feasibility Study of the Treatment of Acute Ischemic Stroke Using the NOVIS Transcarotid Neuroprotection System

NCT04881162
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
NOVIS Transcarotid Neuroprotection System (NPS)
Device
Lead sponsor
Silk Road Medical
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Sep 11, 2026, 2:09 AM EDT