Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 11, 2026, 8:17 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 442 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Medication Abuse Clear all

Conditions: Drug Usage, Drug Abuse, Drug Dependence
Interventions: Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback; Behavioral
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 589 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Delinquency, HIV Risk, Substance Use, Trauma Exposure
Interventions: Integrated intervention for parents and adolescent girls; Behavioral
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 18 Years · Female only
Enrollment: 416 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Eugene, Oregon

Conditions: Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
Interventions: NRP104; Drug
Lead sponsor: New River Pharmaceuticals; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions: Project CHOICE; Behavioral
Lead sponsor: RAND; Other
Eligibility: 11 Years to 15 Years
Enrollment: 6,455 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Abuse Potential
Interventions: Pregabalin 300mg, pregabalin 450 mg, Pregabalin 300 mg with oxycodone 20 mg, pregabalin 450 mg with oxycodone 20 mg, oxycodone 20 mg, Placebo; Drug
Lead sponsor: Viatris Specialty LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Marlton, New Jersey

Conditions: Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use, Opioid Abuse, Uncomplicated, Opioids; Harmful Use, Analgesic Drug Dependence, Orthopedic Disorder
Interventions: Questionnaire; Other
Lead sponsor: St. Louis University; Other
Eligibility: 10 Years to 100 Years
Enrollment: 223 participants
Timeline: 2017 – 2018
U.S. locations: 3
States / cities: St Louis, Missouri

Conditions: Alcohol Use Disorder, Substance Use Disorders, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use Disorders, Drug Use Complicating Pregnancy, Unspecified Trimester
Interventions: Parent-Child Assistance Program - One-Year Version; Behavioral
Lead sponsor: University of Oklahoma; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Enid, Oklahoma • Oklahoma City, Oklahoma

Conditions: Drug Abuse
Interventions: Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET), Enhanced Usual Care (EUC); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 60 Years
Enrollment: 878 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Flint, Michigan

Conditions: Medication Abuse, Harm Reduction
Interventions: Opioid Transitions Clinical Decision Support (CDS); Other
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 12 Years to 89 Years
Enrollment: 200,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Sedative Abuse
Interventions: sodium oxybate, triazolam and pentobarbital; Drug
Lead sponsor: Orphan Medical; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Methamphetamine Addiction
Interventions: Dextroamphetamine, Placebo; Drug
Lead sponsor: California Pacific Medical Center Research Institute; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Drug/Substance Abuse/Addiction, Alcohol Abuse/Addiction
Interventions: Oxford House, Safe Haven, Usual aftercare; Behavioral
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years and older
Enrollment: 270 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: HIV, Opioid Abuse
Interventions: Standard Care, Text Messaging CBT (TXT-CBT); Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Marijuana Use, Opioid Use
Interventions: Marijuana, Opioid; Drug
Lead sponsor: Shanna Babalonis, PhD; Other
Eligibility: 18 Years to 50 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Substance Use Disorder, Delinquency
Interventions: Motivational Enhancement Therapy /Adol and PW for parents, Motivational Enhancement Therapy for adolescents, Drug Education for adolescents, Parenting Wisely for parents, Drug Education for adolescents; Other
Lead sponsor: Oregon Research Institute; Other
Eligibility: 13 Years to 17 Years
Enrollment: 239 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Abuse Potential
Interventions: Placebo, Alprazolam 2 mg, Gabapentin Enacarbil Immediate Release (GE-IR) 200 mg, Gabapentin Enacarbil Immediate Release (GE-IR) 450 mg, Gabapentin Enacarbil Immediate Release (GE-IR) 700 mg; Drug
Lead sponsor: Arbor Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Overland Park, Kansas

Conditions: Cocaine-Related Disorders, Substance-Related Disorders
Interventions: quetiapine; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 65 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Opioid-Related Disorders
Interventions: oxycodone and naltrexone; Drug
Lead sponsor: Pain Therapeutics; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Drug Abuse
Interventions: STAGE-12, Treatment as Usual; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 471 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2010
U.S. locations: 10
States / cities: Jacksonville, Florida • Kaneohe, Hawaii • Columbus, Ohio + 7 more

Conditions: Opioid Dependence
Interventions: buprenorphine/naloxone combination; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2011
U.S. locations: 1
States / cities: New York, New York

Conditions: Substance Abuse, Families, Trauma
Interventions: Multidimensional Family Therapy, Group CBT; Other
Lead sponsor: University of Miami; Other
Eligibility: 13 Years to 17 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 2
States / cities: Miami, Florida • Luling, Louisiana

Conditions: Nicotine Dependence, Drug Abuse
Interventions: Not listed
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 249 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Divorce, Drug Abuse, Mental Health Disorder
Interventions: New Beginnings Program; Behavioral
Lead sponsor: Arizona State University; Other
Eligibility: 3 Years to 18 Years
Enrollment: 2,415 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Substance Abuse
Interventions: Brief Strategic Family Therapy (BSFT), Treatment as Usual; Behavioral
Lead sponsor: University of Miami; Other
Eligibility: 12 Years to 17 Years
Enrollment: 480 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2011
U.S. locations: 7
States / cities: Tucson, Arizona • Tarzana, California • Thornton, Colorado + 4 more

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Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use

The ProGirls Study

Study to Evaluate the Likeability, Safety, and Abuse Potential of NRP 104 in Adults With Histories of Stimulant Abuse

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users

A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries

Evaluating a One-Year Version of the Parent-Child Assistance Program

Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department

Clinical Decision Support for Safety of Opioid Transitions

Physiological, Behavioral and Subjective Effects of Drugs (GHB)

A Pilot Trial of Dextroamphetamine for Methamphetamine Dependence

Evaluating Alternative Aftercare Models for Ex-offenders

Cell Phone Technology Targeting ART Adherence and Drug Use

Reinforcing Effects of Marijuana and Opioids

Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Quetiapine for Cocaine Use and Cravings

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Stimulant Abuser Groups to Engage in 12-Step

Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse

Family-Based Drug Services for Young Disaster Victims

Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI

Multi-court Trial of NBP to Prevent Substance Abuse and Mental Health Disorders (MTC)

Brief Strategic Family Therapy for Adolescent Drug Abusers