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Showing 169–192 of 2,336 matching trials from the local directory fallback.
Recruiting Not applicable Interventional Accepts healthy volunteers

Acute Mental Fatigue and Muscle Strength

NCT07846618
Conditions
Mental Fatigue, Muscle Strength Dynamometer
Interventions
Computer-Based Mental Fatigue Protocol
Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pensacola, Florida
Conditions
ATFL, Ankle, Anterior Talofibular Ligament, Bioinductive Implant, Brostrom Procedure, Chronic Lateral Ankle Instability, Lateral Ankle Instability
Interventions
Brostrom repair with augmentation, Standard Brostrom Repair
Device · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
PMDD, Perimenopause
Interventions
transcutaneous auricular neurostimulation (tAN)
Device
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Lewy Body Dementia Psychosis
Interventions
ACP-204
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
55 Years to 84 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
18
States / cities
Irvine, California • Aventura, Florida • Boca Raton, Florida + 13 more
Conditions
Lewy Body Dementia Psychosis
Interventions
ACP-204, Placebo
Drug
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Eligibility
55 Years to 84 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
30
States / cities
Irvine, California • Aurora, Colorado • Washington D.C., District of Columbia + 23 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Dairy Choline Bioavailability

NCT06902480
Conditions
Post-menopausal Status, Post-menopausal Women
Interventions
WPPC, Whole egg powder
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
51 Years to 70 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Recruiting Not applicable Interventional Accepts healthy volunteers

SBIR/ STTR Family Check-up Online

NCT06876246
Conditions
Academic Achievement, Behavior Problems, Mental Health, Parenting Skills, Parenting Stress
Interventions
FCU Online with Telehealth Coaching, Family Check-Up Online
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
670 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Agitation Associated With Alzheimer's Dementia
Interventions
ITI-1284, Placebo
Drug
Lead sponsor
Intra-Cellular Therapies, Inc.
Industry
Eligibility
55 Years and older
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
31
States / cities
Anaheim, California • Costa Mesa, California • Garden Grove, California + 18 more
Conditions
Critical Illness, Delirium, ICU Acquired Weakness, Implementation Science, Mechanical Ventilation Complication, Pain
Interventions
RN Implementation Facilitator, Realtime audit and feedback
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
16,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Iowa City, Iowa • Omaha, Nebraska • Columbus, Ohio
Conditions
Critical Limb Ischemia, Malnutrition, Nutritional Supplements
Interventions
Ensure Enlive Advanced Nutrition Shake, Ensure Surgery Immunonutrition Shake
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Dementia Caregivers
Interventions
ACT for Caregivers
Behavioral
Lead sponsor
Utah State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Logan, Utah
Conditions
Acute Treatment of Migraine
Interventions
Zavegepant
Drug
Lead sponsor
Pfizer
Industry
Eligibility
6 Years to 11 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
14
States / cities
Washington D.C., District of Columbia • Hinesville, Georgia • Minneapolis, Minnesota + 9 more
Conditions
Amenorrhea, Hypergonadism, Hypogonadism, Late Puberty, Precocious Puberty
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
8 Years to 99 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2039
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Conditions
Cognitive Decline, Healthy Aging, Mild Cognitive Impairment
Interventions
melatonin, placebo
Dietary Supplement · Other
Lead sponsor
Natalie Denburg
Other
Eligibility
56 Years to 85 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Ascending Aorta Aneurysm, Ascending Aortic Aneurysm Enlargement
Interventions
Thoracic Aortic Surgery
Procedure
Lead sponsor
Ottawa Heart Institute Research Corporation
Other
Eligibility
18 Years to 79 Years
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2035
U.S. locations
16
States / cities
San Francisco, California • Iowa City, Iowa • Boston, Massachusetts + 12 more
Conditions
Chronic Myelomonocytic Leukemia, Clonal Cytopenia of Undetermined Significance, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin Lymphoma, Recurrent Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Lymphoma
Interventions
Ascorbic Acid, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Carboplatin, Central Venous Cannula Insertion, Cisplatin, Computed Tomography, Core Biopsy, Cytarabine, Decitabine, Decitabine and Cedazuridine, Dexamethasone, Echocardiography, Etoposide, Gemcitabine Hydrochloride, Ifosfamide, Laboratory Biomarker Analysis, Magnetic Resonance Imaging, Oxaliplatin, Placebo Administration, Portacath Placement, Positron Emission Tomography, Questionnaire Administration, Rituximab
Dietary Supplement · Procedure · Drug + 2 more
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2033
U.S. locations
4
States / cities
Mankato, Minnesota • Rochester, Minnesota • Eau Claire, Wisconsin + 1 more
Conditions
Chronic Weight Management
Interventions
ASC35 Injection B, for subcutaneous use, ASC35 Placebo Injection B, for subcutaneous use, Tirzepatide
Drug
Lead sponsor
Ascletis Pharma (China) Co., Limited
Industry
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Cigarette Use, Menthol Cigarettes, Smoking Behavior
Interventions
Message Exposure via Discrete Choice Experiment
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Santa Barbara, California • Atlanta, Georgia
Conditions
Depressive Disorder, Treatment-Resistant
Interventions
Esketamine 56 mg, Esketamine 84 mg, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years and older
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
7
States / cities
Redlands, California • San Diego, California • Marietta, Georgia + 4 more
Conditions
Caregivers, Dementia, Depression
Interventions
WeACT
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

SAFEGUARD Level Up Study

NCT07286955
Conditions
Mental Health, Performance at Work, Resilience, Risk Reduction Behavior, Risky Behavior, Suicide Prevention
Interventions
Level Up
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Fort Hood, Texas
Conditions
Congenital Heart Disease, Hypoxemia, Skin Pigment
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
Up to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Recruiting Not applicable Interventional

INHANCE Stemless Reverse Shoulder IDE

NCT06323980
Conditions
Arthroplasty, Replacement, Shoulder
Interventions
Reverse Total Shoulder
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
15
States / cities
Atlantis, Florida • Waltham, Massachusetts • Grand Rapids, Michigan + 12 more
Conditions
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder, Conduct Disorder, Obsessive Compulsive Disorder, Typical Development
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
6 Years to 80 Years
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland