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ClinicalTrials.gov public records Last synced Nov 14, 2026, 9:28 PM EST

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Showing 25–48 of 114 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Menopause Hot Flashes Clear all

Conditions: Menopause Hot Flashes
Interventions: Placebo, Fezolinetant; Drug
Lead sponsor: Rebecca Thurston; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Chicago, Illinois • Pittsburgh, Pennsylvania

Conditions: Hot Flushes, Menopause, Postmenopause
Interventions: Esterified Estrogens (EE) and Methyltestosterone (MT); Drug
Lead sponsor: Solvay Pharmaceuticals; Industry
Eligibility: 45 Years to 65 Years · Female only
Enrollment: 1,251 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 88
States / cities: Montgomery, Alabama • Tucson, Arizona • Jonesboro, Arkansas + 69 more

Conditions: Menopause
Interventions: Paced Respiration; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hot Flashes
Interventions: soy isoflavones, Placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: Female only
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2000 – 2001
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Vasomotor Symptoms Associated With Menopause, Hot Flashes
Interventions: Elinzanetant (BAY3427080), Placebo; Drug
Lead sponsor: Bayer; Industry
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 48
States / cities: Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 43 more

Conditions: Hot Flushes
Interventions: vilazodone, placebo capsules; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 45 Years to 60 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Hot Flashes
Interventions: Cenestin 0.3 mg Tablets, Placebo; Drug · Other
Lead sponsor: Duramed Research; Industry
Eligibility: 30 Years to 80 Years · Female only
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 49
States / cities: Huntsville, Alabama • Montgomery, Alabama • Phoenix, Arizona + 40 more

Conditions: Hot Flashes, Menopause
Interventions: Hot Flush Induction; Other
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 70 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Breast Cancer, Hot Flashes, Menopausal Symptoms, Unspecified Adult Solid Tumor, Protocol Specific
Interventions: flaxseed, placebo; Dietary Supplement · Other
Lead sponsor: Alliance for Clinical Trials in Oncology; Other
Eligibility: 18 Years and older · Female only
Enrollment: 210 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 107
States / cities: Aurora, Colorado • Boulder, Colorado • Colorado Springs, Colorado + 71 more

Conditions: Menopause Syndrome, Menopause, Hot Flashes
Interventions: NOE-115; Drug
Lead sponsor: Noema Pharma AG; Industry
Eligibility: 45 Years to 60 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 5
States / cities: San Diego, California • Jacksonville, Florida • Atlanta, Georgia + 2 more

Conditions: Depression, Menopause, Vasomotor Disturbance, Hot Flashes, Sleep
Interventions: vortioxetine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years to 62 Years · Female only
Enrollment: 47 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Menopause, Hot Flashes, Night Waking
Interventions: Elinzanetant (BAY3427080), Placebo; Drug
Lead sponsor: Bayer; Industry
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 199 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 10
States / cities: Mesa, Arizona • San Diego, California • Aventura, Florida + 6 more

Conditions: Hot Flashes
Interventions: MF101; Drug
Lead sponsor: Bionovo; Industry
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 4
States / cities: Berkeley, California • Lincoln, California • Sacramento, California + 1 more

Conditions: Hot Flushes, Hot Flashes
Interventions: Paced Respiration, Music Therapy; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 40 Years to 59 Years · Female only
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Menopause-related Hot Flashes
Interventions: elinzanetant - reference formulation, placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: Hot Flashes, Memory Loss
Interventions: PhytoSERM tablet, placebo; Dietary Supplement
Lead sponsor: University of Southern California; Other
Eligibility: 45 Years to 60 Years · Female only
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Menopause, Hot Flashes, Blood Pressure Regulation
Interventions: High-Resistance Inspiratory Muscle Strength Training, Low-Resistance Inspiratory Muscle Strength Training, POWERbreathe K3 device; Behavioral · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 45 Years to 60 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Vasomotor Symptoms
Interventions: Asimadoline; Drug
Lead sponsor: Tioga Pharmaceuticals; Industry
Eligibility: 40 Years to 62 Years · Female only
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Menopause, Hot Flashes, Mood
Interventions: Shatavari extract, Shatavari + Ashwagandha extract, Placebo; Dietary Supplement
Lead sponsor: SF Research Institute, Inc.; Network
Eligibility: 45 Years to 55 Years · Female only
Enrollment: 51 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hot Flushes, Menopause, Premature, Obesity, Vitamin D Deficiency
Interventions: Vitamin D, Placebo; Dietary Supplement · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 40 Years to 60 Years · Female only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Menopause, Depression, Hot Flashes
Interventions: leuprolide; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hot Flashes
Interventions: Hypnosis, Structured attention; Behavioral · Other
Lead sponsor: Baylor University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 187 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2014
U.S. locations: 1
States / cities: Waco, Texas

Conditions: Menopausal Depression
Interventions: Estradiol, Placebo control; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years and older · Female only
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Menopause Related Conditions
Interventions: Sleepwear with Lateralized Thermal Characteristics, Sham-Lateralized Sleepwear; Device
Lead sponsor: St. Peter's Hospital, Albany, NY; Other
Eligibility: 40 Years to 69 Years · Female only
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Albany, New York

Search by objective public record fields.

Fezolinetant and Vascular Health and Brain Health

Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes

RESPeRATE for Treatment of Hot Flashes

Soy Isoflavone Tablets: Effects on Sleep, Quality of Life, Symptoms and Cognitive Function in Menopausal Women

A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause (OASIS-2)

Vilazodone for Menopausal Hot Flashes

A Clinical Trial to Demonstrate the Efficacy and Safety of Cenestin 0.3 mg for the Treatment of Hot Flashes

The Cardiovascular Impact of Hot Flushes

Flaxseed in Treating Postmenopausal Women With Hot Flashes Who Have a History of Breast Cancer or Other Cancer or Who Do Not Wish to Take Estrogen Therapy

A Study of NOE-115 in Women With Vasomotor Symptoms Due to Menopause

Vortioxetine for Menopausal Depression

A Study of BAY3427080 (NT-814) in the Treatment of Moderate to Severe Post-menopausal Vasomotor Symptoms

A Clinical Trial Assessing Safety of MF101 for Hot Flushes

Menopausal Treatment Using Relaxation Exercises (MaTURE)

Finding Links Between Hot flASHes and CardioVascular Disease

Phytoserms for Menopause Symptoms and Age-Associated Memory Decline

Time-Efficient Inspiratory Muscle Strength Training for Reducing Sympathetic Activity and Improving Sleep in Midlife Women

Safety and Efficacy of Asimadoline (TP0052) in Patients With Vasomotor Symptoms (VMS).

Efficacy and Safety of Shatavari for Treatment of Menopausal Symptoms in Women: A Randomized, Double-blind, Three-arm, Parallel, Placebo-controlled Study

The Role of Vitamin D in Menopause: Relationship to Menopausal Symptoms in Body Composition

Impact of Hot Flashes on Sleep and Mood Disturbance

Hypnosis For Hot Flashes Among Postmenopausal Women in a Randomized Clinical Trial

Effects of Estrogen and Hot Flashes on Mood in Postmenopausal Women

The Effects of Lateralized Thermal Sleepwear on Sleep, Skin Temperature and Skin Moisture in Menopausal Women