- Conditions
- Suicide Risk, Major Depressive Disorder (MDD)
- Interventions
- Suvorexant (dual orexin receptor antagonist)
- Drug
- Lead sponsor
- Marianne Goodman
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- The Bronx, New York
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 481–504
of 1,861
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Major Depressive Disorder
- Interventions
- Desvenlafaxine succinate sustained release 50 mg, Desvenlafaxine succinate sustained release 25 mg, Placebo
- Drug
- Lead sponsor
- Pfizer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 874 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2011
- U.S. locations
- 21
- States / cities
- Beverly Hills, California • Encino, California • Los Alamitos, California + 16 more
- Conditions
- Alcohol Use Disorder (AUD), Major Depressive Disorder (MDD)
- Interventions
- Pregnenolone, Placebo
- Drug
- Lead sponsor
- Sherwood Brown, MD, PhD
- Other
- Eligibility
- 21 Years to 55 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 2
- States / cities
- Dallas, Texas • Richardson, Texas
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State, Unresponsive Wakefulness Syndrome, Brain Injury, TBI Traumatic Brain Injury
- Interventions
- Functional Near-Infrared Spectroscopy Monitoring
- Other
- Lead sponsor
- University of California, Los Angeles
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Bipolar II Disorder, Bipolar II Disorder, Most Recent Episode Major Depressive
- Interventions
- Device: Stimulation-ON, Device: Stimulation-OFF, Device: Stimulation -ON Active Control
- Device
- Lead sponsor
- Andrew Krystal
- Other
- Eligibility
- 22 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2035
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- MAJOR DEPRESSIVE DISORDER
- Interventions
- INFLUENZA VACCINE, NaCl-saline placebo
- Biological · Other
- Lead sponsor
- Laureate Institute for Brain Research, Inc.
- Other
- Eligibility
- 18 Years to 55 Years · Female only
- Enrollment
- 6 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Tulsa, Oklahoma
- Conditions
- Major Depressive Disorder \(MDD, Depressive Disorder, Major
- Interventions
- Active VeNS Device, Sham VeNS Device
- Device
- Lead sponsor
- Neurovalens Ltd.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Substance Abuse, Substance Dependence, Depressive Disorder
- Interventions
- Group interpersonal psychotherapy (IPT-G), Psychoeducation on co-occurring disorders (PSYCHOED)
- Behavioral
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Cranston, Rhode Island
- Conditions
- Depression, Insomnia
- Interventions
- CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS, Repetitive Transcranial Magnetic Stimulation
- Behavioral · Device
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Major Depressive Disorder
- Interventions
- NMRA-335140, Placebo
- Drug
- Lead sponsor
- Neumora Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 430 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 57
- States / cities
- Encino, California • Garden Grove, California • Los Alamitos, California + 42 more
- Conditions
- Major Depressive Disorder
- Interventions
- Brain stimulation
- Procedure
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Major Depressive Disorder
- Interventions
- Cognitive Therapy, Supportive-Expressive Psychodynamic Therapy
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 237 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Restless Leg Syndrome (RLS), Spinal Cord Stimulation (SCS)
- Interventions
- Spinal Cord Stimulation
- Device
- Lead sponsor
- Marshall Holland
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2034
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Major Depressive Disorder
- Interventions
- Ixekizumab
- Drug
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Major Depressive Disorder, Depression
- Interventions
- TC-5214, Placebo
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 2,409 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 79
- States / cities
- Birmingham, Alabama • Tucson, Arizona • Conway, Arkansas + 76 more
- Conditions
- Major Depressive Disorder, Recurrent, Unspecified, Major Depressive Disorder, Single Episode, Unspecified
- Interventions
- H-Coil Deep TMS in combination with SSRIs
- Device
- Lead sponsor
- Brainsway
- Industry
- Eligibility
- 22 Years to 68 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 13
- States / cities
- Davis, California • Los Angeles, California • Santa Monica, California + 9 more
- Conditions
- Major Depression, Cancer, Diabetes, Cardiovascular Diseases
- Interventions
- Desvenlafaxine, Omega 3 Fatty acids, Placebo (for Omega 3 fatty acid supplement)
- Drug · Dietary Supplement
- Lead sponsor
- UConn Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Farmington, Connecticut
- Conditions
- Major Depressive Disorder
- Interventions
- Ketamine, Saline, Magnetic Resonance Imaging (MRI)
- Drug · Procedure
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Major Depressive Disorder
- Interventions
- Aripiprazole 5mg, Aripiprazole 2mg, Placebo
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Chronic Kidney Diseases, Major Depressive Disorder, End Stage Kidney Disease (ESRD)
- Interventions
- Bupropion, Behavioral activation therapy, Placebo, Clinical Management
- Drug · Behavioral · Other
- Lead sponsor
- Stony Brook University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 4
- States / cities
- Stony Brook, New York • Dallas, Texas • Seattle, Washington
- Conditions
- Major Depressive Disorder
- Interventions
- FDA-approved selective-serotonin reuptake inhibitors (SSRIs) and selective-norepinephrine reuptake inhibitors (SNRIs)
- Drug
- Lead sponsor
- Adams Clinical
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Watertown, Massachusetts
- Conditions
- Major Depressive Disorder
- Interventions
- ALTO-300 oral (PO) tablet
- Drug
- Lead sponsor
- Alto Neuroscience
- Industry
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 91 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 11
- States / cities
- Culver City, California • Sacramento, California • Santee, California + 8 more
- Conditions
- Major Depressive Disorder, Nicotine Dependence
- Interventions
- bupropion and smoking cessation behavioral intervention
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Treatment Resistant Depression, Major Depressive Disorder
- Interventions
- Dose-Optimized and Spaced Transcranial Direct Current Stimulation, Spaced Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
- Device
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- San Diego, California