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ClinicalTrials.gov public records Last synced Oct 13, 2026, 8:08 AM EDT

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Showing 169–192 of 1,366 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mental Health Impairment Clear all
Completed Not applicable Interventional Results available

Mnemonic Strategy Versus Spaced Retrieval Training in Those With Mild Cognitive Impairment

NCT04533204
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
mnemonic strategy training, spaced retrieval training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

An Investigation of Chemotherapy Induced Cognitive Impairments in Breast Cancer Survivors

NCT02515487
View directory record Official record
Conditions
Breast Cancer
Interventions
Brain Fitness Program (BFP)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Oct 13, 2026, 8:08 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Evolution of Memory Related Activity

NCT00902499
View directory record Official record
Conditions
Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 90 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2010 · Synced Oct 13, 2026, 8:08 AM EDT
Not listed Phase 2 Interventional

Development and Evaluation of Computerized Olfactory Training Program for Cognitive Decline in Early Alzheimer's Disease

NCT05122598
View directory record Official record
Conditions
Mild Cognitive Impairment, Early Alzheimer's Disease, Memory Impairment
Interventions
COT, Sham
Drug
Lead sponsor
Evon Medics LLC
Industry
Eligibility
55 Years to 95 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Oct 13, 2026, 8:08 AM EDT
Completed No phase listed Observational

Brain Imaging, Nutrition, and Cognition in Breast Cancer Survivors

NCT05122000
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
45 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 13, 2026, 8:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

COPD-Related Physiology and the Brain

NCT03269721
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
Interventions
Neuropsychological Assessment, Spirometry, Arterial Blood Gas, Diffusion Capacity of the Lung for Carbon Monoxide, 6 Minute Walk Test, Systemic Vascular Measures, Blood Biomarkers, Symptom Questionnaire Measures, Brain MRI
Behavioral · Procedure · Diagnostic Test + 1 more
Lead sponsor
Karin Hoth
Other
Eligibility
30 Years to 85 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Results available

Serious Game-based Interventions in Patients With Mild Cognitive Impairment Outside the Clinic

NCT04920123
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neuro-World
Device
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
55 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Amherst, Massachusetts • Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

A Pilot Randomized Controlled Trial: CoINTEGRATE

NCT05732285
View directory record Official record
Conditions
Neurocognitive Disorders, Cognitive Dysfunction, Traumatic Brain Injury, Multiple Sclerosis, Mild Cognitive Impairment
Interventions
CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
21 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

Multimodal Investigation of Post COVID-19 in Females

NCT05225220
View directory record Official record
Conditions
Post COVID-19, Cognitive Dysfunction
Interventions
Parasym Device (of Parasym Ltd, UK) using Transcutaneous Vagus Nerve Stimulation (t-VNS)
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2023 · Synced Oct 13, 2026, 8:08 AM EDT
Recruiting No phase listed Observational

Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

NCT04579120
View directory record Official record
Conditions
Alzheimer Disease
Interventions
[11C]-Pittsburgh Compound B ([11C]PiB), F 18 AV-1451 (Flortaucipir)
Drug
Lead sponsor
Tammie L. S. Benzinger, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Phase 2 Interventional Results available

DASH After TBI Study: Decreasing Adrenergic or Sympathetic Hyperactivity After Traumatic Brain Injury

NCT01322048
View directory record Official record
Conditions
Brain Injuries, Craniocerebral Trauma, Trauma, Nervous System, Traumatic Brain Injury
Interventions
IV Propranolol and Per Tube Clonidine, Placebo
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
16 Years to 64 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Oct 13, 2026, 8:08 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Amyloid Prediction in Early Stage Alzheimer's Disease Through Speech Phenotyping

NCT04928976
View directory record Official record
Conditions
Alzheimer Disease, Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer's Disease (Incl Subtypes), Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
Novoic Limited
Industry
Eligibility
50 Years to 85 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 13, 2026, 8:08 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Biomarkers and Early Alzheimer's Disease

NCT00094952
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2009 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

Cognitive Training in Survivors of Covid-19: A Randomized Trial

NCT04956887
View directory record Official record
Conditions
Covid19, Cognitive Impairment
Interventions
AKL-T01, Control Group
Behavioral · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

Family-Centered Songwriting in Pediatric Palliative Care

NCT04198038
View directory record Official record
Conditions
Cognitive Impairment
Interventions
Songwriting with licensed music therapist
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
7 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation

NCT04647032
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Transcranial alternating current stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Mental Health InSciEd Out

NCT02680899
View directory record Official record
Conditions
Mental Disorders, Substance-Related Disorders, Social Stigma, Mental Health Wellness 1, Mental Health Impairment
Interventions
Curricular Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
12 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 30, 2017 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Results available

eHealth Insomnia Intervention for Adult Survivors of Childhood Cancer

NCT04317742
View directory record Official record
Conditions
Childhood Cancer, Insomnia, Neurocognitive Impairment, Survivorship, Late Effect, Sleep
Interventions
Sleep Healthy Using the Internet (SHUTi) Intervention Group, Online Patient Education (PE) Control Group
Device
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
1,554 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 13, 2026, 8:08 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Post Hoc Analysis and Clinical Data Collection for Subjects Tested With Brain Network Activation (BNA™) Technology

NCT03699514
View directory record Official record
Conditions
Healthy, Cognitive Impairment, Neurological Disorder
Interventions
Brain Network Activation (BNA™) technology
Device
Lead sponsor
ElMindA Ltd
Industry
Eligibility
8 Years to 99 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
4
States / cities
La Jolla, California • Chicago, Illinois • Skokie, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Multimodal Brain Health Intervention for Older African Americans

NCT04863378
View directory record Official record
Conditions
Cognitive Impairment, Mild, Cognitive Decline
Interventions
Walking conversational reminiscence
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
65 Years to 110 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional

A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults

NCT03972384
View directory record Official record
Conditions
Critical Illness, Mechanical Ventilation Complication, Delirium, Cognitive Impairment
Interventions
Post-ICU Problem Solving
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
55 Years to 89 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Not applicable Interventional Results available

Exercise in Adults With Mild Memory Problems

NCT02814526
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
Interventions
Aerobic exercise, Stretching/balance/range of motion exercise
Behavioral
Lead sponsor
Alzheimer's Disease Cooperative Study (ADCS)
Other
Eligibility
65 Years to 89 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
14
States / cities
Irvine, California • Palo Alto, California • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 13, 2026, 8:08 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)

NCT01044758
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI)
Interventions
Levetiracetam 62.5mg, Levetiracetam 125mg, Levetiracetam 250mg, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 85 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Oct 13, 2026, 8:08 AM EDT
Recruiting Phase 2 Interventional

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

NCT05565833
View directory record Official record
Conditions
Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic, Dyssomnias, Sleep Wake Disorders, Nervous System Diseases, Alzheimer Disease
Interventions
SHUTi OASIS, Patient Education
Behavioral · Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 13, 2026, 8:08 AM EDT