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Showing 1–24 of 756 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Metabolic Syndrome X Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Asthma and Obesity Diet Versus Exercise

NCT03644355
View directory record Official record
Conditions
Obesity, Childhood, Asthma in Children, Inflammatory Response, Metabolic Syndrome, Nutrition Poor, Physical Activity, Behavior, Eating, Molecular Biology, Restriction Fragment Length Polymorphisms, Maternal Exposure, Genetic Change
Interventions
Lifestyle counseling
Behavioral
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
13 Years to 19 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Epigenetic Modifications in Obese Aging Women

NCT01977885
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
High Protein Diet, Exercise
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
50 Years to 64 Years · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2015 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors

NCT05473026
View directory record Official record
Conditions
Cancer Survivors, African Americans, Women, Psychology, Positive, Cardiometabolic Syndrome, Exercise, Feasibility Studies, Breast Neoplasm Female
Interventions
Gratitude Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 99 Years · Female only
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Interrupting Prolonged Sitting With Intermittent Exercise on Postprandial Lipemia

NCT03856606
View directory record Official record
Conditions
Metabolic Syndrome X, Atherosclerosis, Insulin Resistance, Hyperinsulinism, Glucose Metabolism Disorders, Metabolic Disease, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Cardiovascular Diseases
Interventions
Prolonged sitting without exercise, Prolonged sitting with interval exercise
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 40 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Sep 14, 2026, 5:11 PM EDT
Not listed No phase listed Observational

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders

NCT00596999
View directory record Official record
Conditions
Hematologic Malignancies
Interventions
UCB and HPDSC
Procedure
Lead sponsor
Celgene Corporation
Industry
Eligibility
Up to 55 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 9, 2012 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soybean Oil Trial of cArdiovascular Risk

NCT02404207
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Metabolic Syndrome
Interventions
Soybean oil, High-oleic soybean oil, High-oleic soybean oil + fully hydrogenated soybean oil, Palm olein + palm stearin
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
30 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Dairy Fat as a Mediator of Vitamin E Adequacy in Individuals With Metabolic Syndrome

NCT01787591
View directory record Official record
Conditions
Non-alcoholic Fatty Liver, Metabolic Syndrome
Interventions
Fat-Free Milk, Low-Fat Milk, Full-Fat Milk, Soy Milk
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2016 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons

NCT00960414
View directory record Official record
Conditions
Obesity
Interventions
SHINE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Sep 14, 2026, 5:11 PM EDT
Enrolling by invitation Not applicable Interventional

Ketogenic Diet in Rheumatoid Arthritis (RA)

NCT05799768
View directory record Official record
Conditions
Rheumatoid Arthritis, Inflammation, Obesity, Ketogenic Dieting, Metabolic Syndrome
Interventions
Ketogenic diet
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Phase 4 Interventional Results available

Endogenous Renin-Angiotensin-Aldosterone System and Glucose Metabolism

NCT02034435
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Low Salt diet plus Placebo tablet, Low Sodium diet plus Salt tablet, Epleronone, Amlodipine
Other · Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 19, 2021 · Synced Sep 14, 2026, 5:11 PM EDT
Active, not recruiting Phase 3 Interventional

A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome

NCT07219602
View directory record Official record
Conditions
Lipidemia, Type 2 Diabetes (T2DM), Metabolic Syndrome (MetS)
Interventions
obicetrapib 10 mg + ezetimibe 10 mg FDC daily, Obicetrapib 10 mg, Placebo
Drug · Other
Lead sponsor
NewAmsterdam Pharma
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
32
States / cities
Sun City West, Arizona • La Jolla, California • Pomona, California + 24 more
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Autonomic Nervous System and the Metabolic Syndrome

NCT00580957
View directory record Official record
Conditions
Obesity
Interventions
Blocked, Intact
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 60 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2016 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the SWW Method Dietary Intervention for HbA1c and Weight Management as a Preventative Intervention in Women

NCT07463417
View directory record Official record
Conditions
Metabolic Syndrome, Obesity & Overweight, Blood Glucose Monitoring, Type 2 Diabetes Prevention
Interventions
SWW Method® Dietary and Lifestyle Intervention
Behavioral
Lead sponsor
Sarah Wragge Wellness
Industry
Eligibility
35 Years to 75 Years · Female only
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health

NCT02066948
View directory record Official record
Conditions
Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
Interventions
wt loss, meal pattern, even, skew
Other · Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
19 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment

NCT02055118
View directory record Official record
Conditions
Hunter Syndrome
Interventions
idursulfase-IT, No IT treatment
Biological · Other
Lead sponsor
Shire
Industry
Eligibility
Up to 18 Years · Male only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
Oakland, California • Chicago, Illinois • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Sep 14, 2026, 5:11 PM EDT
Completed No phase listed Observational

Diet and Activity in Cerebral Palsy

NCT02175108
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
16 Years to 89 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Sep 14, 2026, 5:11 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Noninvasive Biomarkers for Monitoring Cardiometabolic Risk in Children

NCT01465789
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
4 Years to 17 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2013 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional

Effects of White Potato Consumption on Measures of Cardiometabolic Health in Individuals With Type 2 Diabetes Mellitus

NCT04511325
View directory record Official record
Conditions
Type2 Diabetes, Cardiometabolic Syndrome, Arterial Stiffness, Overweight and Obesity
Interventions
Potato Regimen, Refined Grain Regimen
Other
Lead sponsor
Florida State University
Other
Eligibility
45 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 7, 2022 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome

NCT03355469
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Metformin, Placebo, Low Intensity Exercise, High Intensity Exercise
Drug · Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
40 Years to 80 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 14, 2026, 5:11 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans

NCT04911153
View directory record Official record
Conditions
PTSD, Cardiovascular Disease, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 14, 2026, 5:11 PM EDT
Terminated Phase 4 Interventional

Assessing the Efficacy and Safety of Rosiglitazone Added to Standard Therapy for Hepatitis C Genotype 1 With Fatty Liver

NCT00274495
View directory record Official record
Conditions
Chronic Hepatitis C Infection, Fatty Liver
Interventions
Rosiglitazone and Pegasys/Ribavirin
Drug
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2007 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Intensity Physical Activity During Sitting on Glycemic Control and Vascular Function in Obese Individuals

NCT03419754
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Glucose, Fidgetting
Dietary Supplement · Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Sep 14, 2026, 5:11 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Impact of Metabolic Syndrome on Flu Vaccine Efficacy

NCT02653495
View directory record Official record
Conditions
Immune Deficiency, Metabolic Syndrome
Interventions
Influenza vaccine
Biological
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2017 · Synced Sep 14, 2026, 5:11 PM EDT
Completed Not applicable Interventional Results available

P20 Extending Sleep to Reverse Metabolic Syndrome

NCT03596983
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sleep Intervention, Week 2 Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 14, 2026, 5:11 PM EDT