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ClinicalTrials.gov public records Last synced Oct 25, 2026, 6:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 937–960 of 1,515 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed Not applicable Interventional

Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention

NCT05249465
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Health Behavior
Interventions
Core behavioral weight loss intervention, Self-monitoring diet, Self-monitoring weight, Self-monitoring steps
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 25, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional

Continuous Glucose and E-Monitoring to Support Healthy Weight Gain in Pregnancies - The GEM Study

NCT06666257
View directory record Official record
Conditions
Pregnancies at Increased Risk for Excessive Gestational Weight Gain, Ecological Momentary Assessment and Intervention, Continuous Glucose Monitor
Interventions
Continuous Glucose and E-Monitoring to Support Healthy Weight Gain in Pregnancy
Behavioral
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Intervention Mapping to Adapt a Mindfulness-based Intervention for Adults With Diabetes and Emotional Distress

NCT03987841
View directory record Official record
Conditions
Type 2 Diabetes, Stress
Interventions
Integrated MBSR/DSME intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 64 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 25, 2026, 6:05 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Study to Learn About How the Study Medicines Called PF-07976016 and PF-06882961 Are Taken Up by the Body, and if Either of Them Change How the Body Processes the Other Medicine in Otherwise Healthy Adults With Overweight or Obesity

NCT06910839
View directory record Official record
Conditions
Overweight, Obesity
Interventions
PF-07976016, PF-06882961
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Anaheim, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 25, 2026, 6:05 AM EDT
Completed No phase listed Observational

Energy Expenditure and Weight Loss Maintenance

NCT03422380
View directory record Official record
Conditions
Obesity, Weight Change, Body, Weight Loss, Physical Activity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Timeline
2009 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Mechanisms of Health Behavior Change

NCT03192254
View directory record Official record
Conditions
Overweight and Obesity, Diet Modification, Incentives
Interventions
self-monitoring, daily monetary incentives, delayed lump sum monetary incentives
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional Results available

Lifestyle Modification and Lorcaserin for Weight Loss Maintenance

NCT02388568
View directory record Official record
Conditions
Obesity
Interventions
Lorcaserin, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 65 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Oct 25, 2026, 6:05 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Age-Related Changes in Body Composition

NCT01517113
View directory record Official record
Conditions
Hypertension, Atherosclerosis
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional

MyLife: A Digital Health Coaching Program

NCT03529903
View directory record Official record
Conditions
Lifestyle-related Condition, Obesity, Sedentary Lifestyle, PreDiabetes, Hypertension
Interventions
Health Coaching
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 25, 2026, 6:05 AM EDT
Terminated Not applicable Interventional Results available

PDA+: A Personal Digital Assistant for Obesity Treatment

NCT00371462
View directory record Official record
Conditions
Obesity, Pain
Interventions
Use of PDA + support to reduce weight and pain, MOVE! level 2 group weight loss counseling
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 25, 2026, 6:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

The WISE (Weightloss Intervention Surgical Effects) Brain Study

NCT02137070
View directory record Official record
Conditions
Diabetes, Weightloss
Interventions
Bariatric Surgery Candidates, Non surgical/Community volunteers
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
20 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

CYP2B6 Genetics and Drug Interactions in Healthy Volunteers

NCT02401256
View directory record Official record
Conditions
Healthy
Interventions
Efavirenz, Bupropion, Rosuvastatin, Montelukast
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 49 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Oct 25, 2026, 6:05 AM EDT
Completed No phase listed Observational

Ghrelin Changes After Roux-en-Y Gastric Bypass

NCT00765596
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Liquid diet for 3 days
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 17, 2011 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Changing Physical Activity Behavior in Individuals With Type 2 Diabetes Using Counceling and Information From Continuous Glucose Monitoring

NCT00542698
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Effect of Physical Activity on Type II Diabetes Mellitus
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
19 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
2
States / cities
Pittsfield, Massachusetts • Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 11, 2007 · Synced Oct 25, 2026, 6:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families

NCT00986011
View directory record Official record
Conditions
Healthy, no Evidence of Disease, Obesity, Weight Changes
Interventions
questionnaire administration, study of socioeconomic and demographic variables, survey administration, study of high risk factors
Other · Procedure
Lead sponsor
University of Southern California
Other
Eligibility
Not listed
Enrollment
780 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 25, 2026, 6:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Diet Composition on Weight Change and Metabolic Parameters

NCT01642849
View directory record Official record
Conditions
Obesity, Inflammation
Interventions
high protein diet, high carbohydrate diet
Dietary Supplement
Lead sponsor
University of Tennessee
Other
Eligibility
20 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 17, 2012 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional

Enlighten: An Adaptive Technology Weight Loss Intervention

NCT01855932
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Technology Supported
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2013 · Synced Oct 25, 2026, 6:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

NCT06613204
View directory record Official record
Conditions
Frontotemporal Dementia, Caregiver Burden, Primary Progressive Aphasia (PPA), Corticobasal Syndrome
Interventions
STELLA-FTD Control, STELLA-FTD Test
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 25, 2026, 6:05 AM EDT
Terminated Not applicable Interventional

The Effect of Structured Lifestyle Modification and Yoga Practice on Metabolic Processes Associated With Cardiovascular Disease

NCT05250310
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Chair Yoga
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Approaches for Improving Long-term Weight Loss

NCT03799289
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss followed by yoga instruction, Behavioral weight loss followed by cooking/dietary education instruction
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 25, 2026, 6:05 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Immune Responses to Gluten

NCT05209568
View directory record Official record
Conditions
Celiac Disease, Malabsorption Syndromes, Digestive System Disease, Intestinal Disease, Gastrointestinal Diseases, Gluten Sensitivity, Celiac Disease in Children
Interventions
Gluten Powder
Dietary Supplement
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 101 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 25, 2026, 6:05 AM EDT
Not yet recruiting Phase 2 Interventional

A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes

NCT07890376
View directory record Official record
Conditions
Obesity, Overweight
Interventions
LY4086940, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
39
States / cities
Chandler, Arizona • Scottsdale, Arizona • Tucson, Arizona + 35 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 25, 2026, 6:05 AM EDT
Completed Phase 3 Interventional

DYNAMIC Study: (Diabetes Nurse Case Management And Motivational Interviewing for Change)

NCT00308386
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension, Hyperlipidemia
Interventions
Nurse Case Management intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
Hershey, Pennsylvania • Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 25, 2026, 6:05 AM EDT