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ClinicalTrials.gov public records Last synced Oct 16, 2026, 4:03 AM EDT

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Showing 769–792 of 6,284 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism and Nutrition Disorder Clear all
Recruiting Phase 2 Interventional

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

NCT05082519
View directory record Official record
Conditions
B-cell Acute Lymphoblastic Leukemia, Obesity
Interventions
IDEAL2 Intervention
Behavioral
Lead sponsor
Etan Orgel
Other
Eligibility
7 Years to 25 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2032
U.S. locations
16
States / cities
Los Angeles, California • Orange, California • San Francisco, California + 13 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Metabolic Effects of Different Weight Loss Diets

NCT00422630
View directory record Official record
Conditions
Metabolic Syndrome X, Obesity, Insulin Resistance, Hypertension, Diabetes
Interventions
The DASH diet, The low glycemic Index Diet, Reduced calorie American Diet
Behavioral
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2011 · Synced Oct 16, 2026, 4:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Response of Gut Microbiota and Cardiometabolic Biomarkers to Consumption of Walnuts

NCT04307628
View directory record Official record
Conditions
Healthy, Normal Weight, Overweight, Obese
Interventions
Walnut, Nut-Free
Other
Lead sponsor
University of California, Davis
Other
Eligibility
20 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Oct 16, 2026, 4:03 AM EDT
Terminated Phase 3 Interventional

Randomization of Early Diabetes Screening Among Obese Pregnant Women.

NCT03116009
View directory record Official record
Conditions
Gestational Diabetes
Interventions
Screening for diabetes with 1-hour GCT and HbA1
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Oct 16, 2026, 4:03 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Effect of EGCG on the Body's Response to Insulin

NCT00434499
View directory record Official record
Conditions
Hypertension, Obesity, Type 2 Diabetes, Insulin Resistance
Interventions
EGCG
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet Obesity Treatment Enhanced With Motivational Interviewing

NCT01232699
View directory record Official record
Conditions
Obesity
Interventions
Internet Obesity Treatment, Internet Obesity Treatment with MI, Contingent MI
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Little Rock, Arkansas • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 16, 2026, 4:03 AM EDT
Not yet recruiting Phase 1 Interventional

Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients

NCT07224087
View directory record Official record
Conditions
Obesity, Smoking Cessation, Bariatric Surgery Patients
Interventions
Naltrexone Hydrochloride, Bupropion HCl Extended Release, Cognitive-Behavioral Therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Withdrawn Phase 4 Interventional

The Effect of add-on Canagliflozin in Patients With Type 2 Diabetes Treated With U-500 Insulin

NCT02597309
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Canagliflozin
Drug
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional

Laparoscopic Gastric Plication Operation for Patients With Severe or Morbid Obesity

NCT01207609
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic Gastric Plication
Procedure
Lead sponsor
Ponce, Jaime, M.D.
Individual
Eligibility
18 Years to 60 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Dalton, Georgia • Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 16, 2026, 4:03 AM EDT
Not listed Not applicable Interventional

Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders

NCT05138198
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Overweight and Obesity, Metabolic Syndrome, Inflammation
Interventions
Mediterranean Diet & Physical Activity, Usual Care
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
40 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Commack, New York
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Oct 16, 2026, 4:03 AM EDT
Terminated Phase 4 Interventional Results available

LOSS- Louisiana Obese Subjects Study

NCT00115063
View directory record Official record
Conditions
Obesity
Interventions
group sessions, sibutramine, orlistat, diethylpropion, Low Calorie Diet, Health One, Intensive Medical Combination Therapy for Obesity, Control Condition
Behavioral · Drug · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 60 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

The Effects of Exenatide (Byetta ) on Energy Expenditure and Weight Loss in Nondiabetic Obese Subjects

NCT00856609
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Byetta (exenatide), Weight loss, Metabolic Chamber, Placebo
Drug · Behavioral · Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 55 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 16, 2026, 4:03 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation

NCT06299098
View directory record Official record
Conditions
Obesity
Interventions
Trevogrumab-Part A, Trevogrumab-Part B and Part C, Garetosmab, Semaglutide, Matching Placebo-Part A, Matching Placebo-Trevogrumab, Matching Placebo-Garetosmab
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,005 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
58
States / cities
Anniston, Alabama • Cullman, Alabama • Phoenix, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of mHealth Applications in Weight Management in a Population Affected by Overweight or Obesity

NCT05726942
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Healthi
Other
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Estrogen Deficiency on Energy Expenditure

NCT01846728
View directory record Official record
Conditions
Obesity
Interventions
Estrogen suppression
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adverse Metabolic Effects of Dietary Sugar

NCT02548767
View directory record Official record
Conditions
Chronic Disease of Cardiovascular System, Type 2 Diabetes, Obesity
Interventions
high fructose corn syrup, aspartame, Energy-balanced diet, Ad libitum diet
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
3
States / cities
Davis, California • Sacramento, California • Vallejo, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Regulation of Muscle Protein Phenotype in Humans With Obesity

NCT04700800
View directory record Official record
Conditions
Obesity
Interventions
Exercise
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 45 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 16, 2026, 4:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Interoception and Eating Behaviors in Children

NCT06504654
View directory record Official record
Conditions
Obesity, Childhood, Eating Behavior
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
7 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Nutrition Physical Activity Tool Use During Well Child Visits

NCT02067728
View directory record Official record
Conditions
Obesity
Interventions
FNPA tool, Usual Care
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
4 Years to 17 Years
Enrollment
430 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Oct 16, 2026, 4:03 AM EDT
Withdrawn Phase 2 Interventional

Anti-psychotic Medication (Stable Dose) Weight Loss Study

NCT01272765
View directory record Official record
Conditions
Obesity
Interventions
Placebo, IHBG-10
Other · Dietary Supplement
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 1, 2012 · Synced Oct 16, 2026, 4:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic

NCT03552107
View directory record Official record
Conditions
Obesity, Weight Loss, Overweight
Interventions
Lorcaserin
Drug
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Oct 16, 2026, 4:03 AM EDT
Completed Not applicable Interventional Results available

Financial Incentives for Maintenance of Weight Loss

NCT01900392
View directory record Official record
Conditions
Obesity
Interventions
Financial incentive
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 80 Years
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Oct 16, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EAT: A Reliable Eating Assessment Technology for Free-living Individuals

NCT06118528
View directory record Official record
Conditions
Wearable Electronic Device
Interventions
Blur Obfuscation, Cartoon Obfuscation, Edge Obfuscation, No Obfuscation (raw)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 16, 2026, 4:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Obesity on Microvascular Insulin Action and Cardiorespiratory Fitness in Type 1 Diabetes

NCT07573228
View directory record Official record
Conditions
Type 1 Diabetes, Overweight
Interventions
Exercise training
Other
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 16, 2026, 4:03 AM EDT