Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 16, 2026, 3:16 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1033–1056 of 6,284 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Glucagon Administration on Energy Expenditure

NCT02237053
Conditions
Hyperglucagonemia, Obesity
Interventions
Glucagon, Octreotide, Placebo, Insulin
Drug · Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Obesity, Immune Deficiency
Interventions
Institutional standard intravenous immune globulin treatment
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Somerville, New Jersey
Conditions
Obesity, Heart Failure
Interventions
NNC0487-0111, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
5,610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
206
States / cities
Alexander City, Alabama • Birmingham, Alabama • Fairhope, Alabama + 173 more
Conditions
Morbid Obesity
Interventions
IV acetaminophen, IV normal saline
Drug
Lead sponsor
McLaren Regional Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Flint, Michigan
Conditions
Obesity
Interventions
Zonisamide SR placebo/ bupropion SR placebo, Zonisamide SR placebo/ bupropion SR 360 mg/day, Zonisamide SR 120 mg/day/ bupropion SR placebo, Zonisamide SR 360 mg/day/ bupropion SR placebo, Zonisamide SR 120 mg/day/ bupropion SR 360 mg/day, Zonisamide SR 360 mg/day/ bupropion SR 360 mg/day
Drug
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
729 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
20
States / cities
Fairhope, Alabama • La Jolla, California • Denver, Colorado + 17 more
Conditions
Breast Cancer
Interventions
Tailored Lifestyle Intervention (TLI), Commercial Weight Loss Program (CWLP)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Conditions
Obesity
Interventions
Standard, Early Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Obesity
Interventions
Standard Lifestyle Intervention, Modified Lifestyle Intervention
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional

Preventing Diabetes in Latino Youth

NCT02615353
Conditions
Obesity, Diabetes
Interventions
Intensive Lifestyle Intervention, Usual Care Control
Behavioral · Other
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 16 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Chronic Disease, Obesity, Hypertension, Diabetes, Self Care, Medication Adherence
Interventions
Active and Healthy Brotherhood (AHB)
Behavioral
Lead sponsor
Gramercy Research Group
Other
Eligibility
21 Years to 64 Years · Male only
Enrollment
332 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Osteoporosis, Vascular Calcification, Inflammation
Interventions
Vitamin K
Drug
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
60 Years to 80 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Obesity
Interventions
Numberless BDS, Digital Scale, Modified Motivational Interviewing
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
12 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
2
States / cities
League City, Texas • Webster, Texas
Conditions
Obesity
Interventions
Peep Belt
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
19 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Obesity
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Overweight
Interventions
Not listed
Lead sponsor
University at Buffalo
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Buffalo, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women

NCT04114071
Conditions
Obesity
Interventions
TOSS Feasibility + Fitbit Community = Reduced Obesity in Older Black Women
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Birmingham, Alabama
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Interplay of Central and Peripheral Vascular Effects of Insulin in Obesity

NCT07653464
Conditions
Obesity (BMI>30), Insulin Resistance
Interventions
human insulin
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Columbia, Missouri
Conditions
Type II Diabetes Mellitus, Obesity
Interventions
Gastric Band, Gastric Sleeve, Gastrostomy Tube
Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Greenville, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function

NCT06776081
Conditions
Obesity, Weight Loss
Interventions
Weight loss without pharmacotherapy
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
40 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boulder, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Epigenetics, DNA Methylation Patterns and Periodontal Disease

NCT01399034
Conditions
Periodontal Disease
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Morbid Obesity
Interventions
Gastric Plication
Procedure
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Cleveland, Ohio • Columbus, Ohio
Conditions
Chronic Kidney Diseases, Obesity
Interventions
SLIMM, Standard Resistance Training, Guided Resistance Training, Placebo, Semaglutide
Behavioral · Drug
Lead sponsor
Srinvasan Beddhu
Other
Eligibility
20 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Stanford, California • Salt Lake City, Utah
Completed Not applicable Interventional

Noom Coach for Bariatric Surgery

NCT03386006
Conditions
Obesity
Interventions
Noom Coach for Bariatric Health
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Obesity
Interventions
referral to comprehensive weight management clinic
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota