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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:05 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 93 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Microbiome, Human Clear all

Conditions: Influenza
Interventions: IIV Flu Vaccine, Metronidazole, Neomycin, Vancomycin; Drug
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Anxiety, Microbiome, Mood Disorders, Neurodegeneration, Depression
Interventions: Not listed
Lead sponsor: Endominance; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Irvine, California

Conditions: Microbial Colonization, Metabolic Syndrome
Interventions: High pulse consumption; Dietary Supplement
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 20 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Malignant Central Nervous System Neoplasm
Interventions: Non-Interventional Study; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Intestinal Bacteria Flora Disturbance
Interventions: Pressed Juice; Dietary Supplement
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 50 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota, Colorectal Neoplasms, Metabolomics
Interventions: Modified Plant-Based Mediterranean Diet; Dietary Supplement
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Diego, California

Conditions: Inflammation, Vaccine, Intestinal Permeability, Typhoid Fever
Interventions: Inulin, Maltodextrin, Ty21a Typhoid Fever Vaccine; Dietary Supplement · Biological
Lead sponsor: USDA, Western Human Nutrition Research Center; Federal
Eligibility: 18 Years to 59 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Davis, California

Conditions: Inflammation, Metabolic Disorder, Hypertriglyceridemia
Interventions: Aronia juice, Placebo; Dietary Supplement · Other
Lead sponsor: Montana State University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Bozeman, Montana

Conditions: Human Microbiome
Interventions: Newborn exposure to mother vaginal microbiota; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 40 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Colorectal Cancer, Inflammation, Nutrition Related Cancer
Interventions: IMAGINE HEALTHY; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 9 Years to 55 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: End Stage Renal Disease (ESRD)
Interventions: AGE; Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 103 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Human Microbiome, Metagenome, Contraception, Cytokine
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Menopausal Complaints, Vaginal Atrophy, Genitourinary Symptoms, HIV (Human Immunodeficiency Virus), Menopause Related Conditions, Vaginitis, Perimenopause
Interventions: Vaginal estradiol tablets, Vaginal moisturizer; Drug · Other
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 40 Years to 70 Years · Female only
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Head and Neck Cancer, Lip Cancer, Oral Cancer, Pharynx Cancer
Interventions: Metagenomic sequencing, Metabolic analysis; Diagnostic Test
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 18 Years to 100 Years
Enrollment: 60 participants
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure, Microbial Colonization
Interventions: Protein-enriched human milk diet, Usual human milk diet; Procedure
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 1 Day to 4 Days
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Human Microbiome
Interventions: Terminalia Chebula fruit extract, Placebo, Topical Terminalia Chebula, Topical Placebo; Dietary Supplement · Other
Lead sponsor: Integrative Skin Science and Research; Industry
Eligibility: 25 Years to 55 Years · Female only
Enrollment: 58 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Infertility
Interventions: 16S rRNA gene sequencing; Diagnostic Test
Lead sponsor: Reproductive Medicine Associates of New Jersey; Other
Eligibility: 18 Years to 45 Years
Enrollment: 332 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Basking Ridge, New Jersey

Conditions: Healthy Adult Participants
Interventions: Fiber Blend 1 (Low Dose), Fiber Blend 2 (High Dose), Placebo; Dietary Supplement · Other
Lead sponsor: LOAM Science; Other
Eligibility: 18 Years to 60 Years
Enrollment: 87 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: West Hollywood, California

Conditions: Healthy
Interventions: Desonide 0.05%, Ketoconazole 2%; Drug
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2026
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Healthy
Interventions: Medium chain triglycerides, Long chain triglycerides; Dietary Supplement
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma, Atrial Fibrillation, Cancer Brain, Cancer, Breast, Cancer Colon, Cancer, Lung, Cancer, Ovarian, Cancer Prostate, Cancer Skin, Throat Cancer, Lymphoma, Cancer, Thyroid, Cancer, Other, Cerebral Palsy, Chronic Fatigue Syndrome, Cluster Headache, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Diseases, Crohn Disease, Deafness, Depression, Diabetes, Eczema, Epilepsy, Fibroids, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Irritable Bowel Syndrome (IBS), Infertility, Lyme Disease, Macular Degeneration, Migraine, Multiple Allergies, Multiple Sclerosis, Osteoarthritis, Osteoporosis, Ovarian Cysts, Parkinson Disease, Phantom Limb Pain, Psoriasis, Post Traumatic Stress Disorder (PTSD), Rheumatoid Arthritis, Sjogrens Disease, Spinal Cord Injury, Spinal Stenosis, Stroke, Tension Headache, Tinnitus, Ulcerative Colitis
Interventions: Advanced multi-component meditation practice; Behavioral
Lead sponsor: Tobias Moeller-Bertram; Industry
Eligibility: 21 Years and older
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Palm Desert, California

Conditions: Human Microbiome
Interventions: Non-interventional; Other
Lead sponsor: Danisco; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 52 participants
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Beltsville, Maryland

Conditions: Influenza
Interventions: Biospecimen Collection, Questionnaire Administration; Procedure · Other
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Feeding, Human Microbiome
Interventions: Intervention education, Placebo Education; Other
Lead sponsor: University of Virginia; Other
Eligibility: Not listed
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Charlottesville, Virginia

Search by objective public record fields.

Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics

Microbiome, Anxiety and Cognitive Orientation Study

Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants

Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research

The Effect of Fruit/Vegetable Drinks on the Human Intestine

Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy

WHNRC (Western Human Nutrition Research Center) Fiber Intervention Study

Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome

Potential Restoration of the Infant Microbiome

Reducing Metabolic Dysregulation in Dyads

Food Preparation Effects on Gut Bacteria in Patients on Peritoneal Dialysis

Changes in Vaginal, Cervical and Uterine Microflora With Levonorgestrel Intrauterine Device Placement

Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV

Microbiome in Head and Neck Squamous Cell Carcinoma

Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk

The Effects of Terminalia Chebula Fruit Extract on the Gut Microbiome and Skin Biophysical Properties

The Human Microbiome and IVF Outcomes

Safety and Efficacy of a Prebiotic Blend in Healthy Humans

Alternation in the Human Microbiome With Commonly Used Topical Medications

MiCrobiome dieT Study

Quest to Analyze One Thousand Humans Meditating

Isolation and Characterization of Multiple Microbial Species From Diverse Healthy Adults

Association Between Gut Microbiome and Dietary Determinants and Vaccine Response

Human Milk and Infant Intestinal Microbiome Study