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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Completed No phase listed Observational

Deciphering the Mechanisms Involved in Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis

NCT02400216
View directory record Official record
Conditions
Cirrhosis
Interventions
dual cholate
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Predicting Adenomatous Polyps in the Colon Using Images of a Human Tongue

NCT06305364
View directory record Official record
Conditions
Colorectal Neoplasms, Gastrointestinal Microbiome
Interventions
Gixam
Device
Lead sponsor
Jubaan Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impacts of Fruit on the Gut Health and Human Health

NCT05063929
View directory record Official record
Conditions
Cardiometabolic Health, Healthy Aging, Cognition
Interventions
Fruit (2 cup eq), Fruit restriction (1/2 cup eq)
Other
Lead sponsor
San Diego State University
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome

NCT05255718
View directory record Official record
Conditions
Inflammation, Metabolic Disorder, Hypertriglyceridemia
Interventions
Aronia juice, Placebo
Dietary Supplement · Other
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 25, 2026, 8:04 AM EDT
Recruiting No phase listed Observational

Optimizing Nutrition and Milk (Opti-NuM) Project

NCT06870981
View directory record Official record
Conditions
Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification, Human Milk Microbiome, Human Milk Feeding, Human Milk Nutrition, Growth &Amp; Development
Interventions
Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.
Other
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
1 Hour to 21 Days
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
2
States / cities
Palo Alto, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Human Microbiome and Healthcare Associated Infections - Nursing Home Dwelling Older Veterans

NCT04218799
View directory record Official record
Conditions
Human Microbiome
Interventions
Intranasal Mupirocin and Topical Chlorhexidine
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Baltimore, Maryland • Perry Point, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Milk in Life Conditions (MiLC): Bacterial Composition of Human Milk Pumped and Stored in "Real-Life" Conditions

NCT03123874
View directory record Official record
Conditions
Human Milk Microbiome, Bacterial Growth
Interventions
Sterile pump set-up, Mother's Own pump set-up
Device
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Sep 25, 2026, 8:04 AM EDT
Active, not recruiting Early Phase 1 Interventional

The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease

NCT06113003
View directory record Official record
Conditions
HIV, Non-Alcoholic Fatty Liver Disease, Metabolic-Associated Steatotic Liver Disease
Interventions
Prebiotic, Probiotic
Dietary Supplement
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)

NCT02127125
View directory record Official record
Conditions
Insulin Sensitivity
Interventions
Maltodextrin, Synbiotic, Sevelamer
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans

NCT03039023
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
Choline Bitartrate, Pre-cooked, pre-peeled whole hardboiled eggs, Egg whites from pre-cooked, pre-peeled hardboiled eggs, Phosphatidylcholine capsules
Dietary Supplement · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Potential Restoration of the Infant Microbiome

NCT02407184
View directory record Official record
Conditions
Human Microbiome
Interventions
Newborn exposure to mother vaginal microbiota
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 40 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Elderberry Consumption and Human Health

NCT06626373
View directory record Official record
Conditions
Obesity, Unspecified
Interventions
Elderberry Juice, Placebo Beverage
Other
Lead sponsor
Washington State University
Other
Eligibility
22 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adult HMO Supplementation and the Gut Microbiome

NCT06570330
View directory record Official record
Conditions
Healthy Adults
Interventions
SuperHMO, Non-GMO corn Maltodextrin, Rapid Absorption
Dietary Supplement
Lead sponsor
Seeding Inc
Industry
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Microbiome Derived Metabolism and Pharmacokinetics

NCT05065671
View directory record Official record
Conditions
Microbial Colonization
Interventions
Tolcapone 100 MG, Duloxetine 20 MG
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Somerville, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional

Combining HIIT and n-3 PUFA to Reduce Inflammation and Improve Metabolic Health

NCT05295719
View directory record Official record
Conditions
Obesity, Inflammation, Human Microbiome, Insulin Resistance, Dyslipidemias
Interventions
Omega-3 polyunsaturated fatty acid, High-Intensity Interval Training, Safflower oil, Low-intensity training
Dietary Supplement · Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 25, 2026, 8:04 AM EDT
Completed No phase listed Observational

The Human Microbiome and IVF Outcomes

NCT03637777
View directory record Official record
Conditions
Infertility
Interventions
16S rRNA gene sequencing
Diagnostic Test
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 45 Years
Enrollment
332 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 25, 2026, 8:04 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Intervention on Inflammation and Microbiome Composition Post-Colonoscopy

NCT06603519
View directory record Official record
Conditions
Colorectal Polyp, Inflammation, Dietary Intervention, Microbiota, Colorectal Neoplasms, Metabolomics
Interventions
Modified Plant-Based Mediterranean Diet
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Prolonged Fasting on Microbiome and HDL

NCT03487679
View directory record Official record
Conditions
Fasting
Interventions
Fasting
Other
Lead sponsor
University of California, Davis
Other
Eligibility
20 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Terminalia Chebula Fruit Extract on the Gut Microbiome and Skin Biophysical Properties

NCT04597502
View directory record Official record
Conditions
Human Microbiome
Interventions
Terminalia Chebula fruit extract, Placebo, Topical Terminalia Chebula, Topical Placebo
Dietary Supplement · Other
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
25 Years to 55 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Sep 25, 2026, 8:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation

NCT03907501
View directory record Official record
Conditions
Human Microbiome
Interventions
Synbiotic, Probiotic, Placebo
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
65 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 5, 2023 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Cultures Before and After Decolonization in Community Dwelling Adults With Current S. Aureus Colonization

NCT04222699
View directory record Official record
Conditions
Human Microbiome
Interventions
Mupirocin calcium ointment, 2%, Topical Chlorhexidine, 4%
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Sep 25, 2026, 8:04 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants

NCT07043712
View directory record Official record
Conditions
Microbial Colonization, Metabolic Syndrome
Interventions
High pulse consumption
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 25, 2026, 8:04 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Dogs as Probiotics

NCT02343731
View directory record Official record
Conditions
Health of the Human Microbiome
Interventions
Introduction of a dog into the home
Other
Lead sponsor
University of Arizona
Other
Eligibility
50 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Sep 25, 2026, 8:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Agro-ecological Farming Systems on Human Health

NCT05575258
View directory record Official record
Conditions
Inflammatory Response
Interventions
44-Day Diet Conventionally Sourced - YELLOW Diet, 44-Day Diet Agro-Ecologically Sourced - GREEN Diet
Other
Lead sponsor
Utah State University
Other
Eligibility
35 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Sep 25, 2026, 8:04 AM EDT