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Showing 1–24 of 88 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Middle Schools Clear all
Completed Not applicable Interventional Accepts healthy volunteers

YES! We Can PLAY: A Physical Activity and Nutrition After-School Program for Middle School Students

NCT04132869
View directory record Official record
Conditions
Child Obesity
Interventions
Sports Readiness Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
11 Years to 15 Years
Enrollment
298 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Yoga for Substance Use Risk Factors in a School Setting

NCT01821950
View directory record Official record
Conditions
Adolescent Development
Interventions
Yoga during physical education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
11 Years to 14 Years
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Linking Lives: Building Quality Parent Components for School-Based Health Programs in Middle Schools

NCT00136279
View directory record Official record
Conditions
Smoking, Sexual Behavior
Interventions
Linking Lives parent-based intervention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
Not listed
Enrollment
9,510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2009 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Results available

Patient Centered Enhancements in School Behavioral Health

NCT03901274
View directory record Official record
Conditions
Mental Health
Interventions
Wellness, Partnership
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
2,558 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Baltimore, Maryland • Charleston, South Carolina • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 22, 2026, 10:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Preventing Sexual Violence Among Middle School Boys With a Strengths-Based Curriculum

NCT03392597
View directory record Official record
Conditions
Sexual Violence
Interventions
Brothers as Allies, Programming-as-Usual
Behavioral
Lead sponsor
New York State Department of Health
Government
Eligibility
12 Years to 14 Years · Male only
Enrollment
720 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 14, 2019 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility Study of a Web-based Program to Help Parents of Middle School Students Effectively Communicate With Their Children About Substance Use

NCT05900115
View directory record Official record
Conditions
Substance Use, Parenting, Communication
Interventions
Media Ready Parent, Active Control Program
Behavioral
Lead sponsor
Innovation Research & Training
Other
Eligibility
10 Years and older
Enrollment
576 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Jul 22, 2026, 10:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Connect Through PLAY: A Staff-based Physical Activity Intervention for Middle School Youth

NCT03732144
View directory record Official record
Conditions
Physical Activity, Obesity Prevention
Interventions
Connect Staff-based PA intervention, Connect Health Curriculum Control
Behavioral · Other
Lead sponsor
University of South Carolina
Other
Eligibility
9 Years to 16 Years
Enrollment
1,350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Tobacco Zero: Interactive Tobacco Education for Teens

NCT00670995
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Interactive Tobacco Education
Behavioral
Lead sponsor
Deschutes Research, Inc.
Other
Eligibility
11 Years to 15 Years
Enrollment
1,864 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Jul 22, 2026, 10:03 AM EDT
Terminated Not applicable Interventional

Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students

NCT05321563
View directory record Official record
Conditions
Adolescent Behavior, Substance Use, Youth, Health Risk Behaviors
Interventions
iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years to 22 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Jul 22, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

NCT06047041
View directory record Official record
Conditions
Mental Health Issue
Interventions
EIS Only, EIS + ECHO
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
10 Years to 99 Years
Enrollment
21,350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Columbia, Missouri • Columbia, South Carolina • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Health Information Technology for COVID-19 Testing in Schools (SCALE-UP Counts)

NCT05112900
View directory record Official record
Conditions
COVID-19
Interventions
Text Messaging (TM), Text Messaging + Health Navigation (TM+HN)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
Not listed
Enrollment
7,122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Jul 22, 2026, 10:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

HOPS Study: A Conceptual Replication

NCT04465708
View directory record Official record
Conditions
Executive Dysfunction, Attention Deficit Hyperactivity Disorder
Interventions
Homework, Organization, and Planning Skills
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
11 Years to 15 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pink and Dude Chef

NCT01803997
View directory record Official record
Conditions
Child Nutrition, Fruit and Vegetable Intake, Healthy Food Choice, Healthy Food Preparation
Interventions
Pink and Dude Chef Afterschool Cooking Program
Behavioral
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
11 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Mar 8, 2015 · Synced Jul 22, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing ALERT With GTO in Middle Schools

NCT05219422
View directory record Official record
Conditions
Substance Abuse
Interventions
Project ALERT, Getting to Outcomes
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Implementing School Wide PBS in Middle Schools: The Foundation for Effective Prevention

NCT04711681
View directory record Official record
Conditions
Substance Abuse, Mental Health
Interventions
Positive Behavior Supports in Middle Schools
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
11 Years to 15 Years
Enrollment
13,498 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2015
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students

NCT00167505
View directory record Official record
Conditions
Sexually Transmitted Diseases, Pregnancy, HIV Infections
Interventions
Risk Avoidance Intervention, Risk Reduction Intervention
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
11 Years to 16 Years
Enrollment
1,742 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2010 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional

Peer-Administered Asthma Self-Management Intervention in Urban Middle Schools

NCT03446365
View directory record Official record
Conditions
Asthma
Interventions
ASMAS, Asthma education plus child health
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 14 Years
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Gratitude Journaling in the Classroom

NCT07061483
View directory record Official record
Conditions
Healthy
Interventions
Experimental (Gratitude Journaling), Control (journaling without gratitude)
Behavioral
Lead sponsor
Michael Rhoads
Other
Eligibility
9 Years to 18 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Grand Junction, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Jul 22, 2026, 10:03 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Best Possible Self-Tech for Middle Schoolers

NCT07540819
View directory record Official record
Conditions
Technology Use, Positive Affect
Interventions
Best Possible Self-Tech
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 22, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

NCT06942455
View directory record Official record
Conditions
Sleep, Sleep Quality, Intervention Study, Ethnic Minority
Interventions
SIESTA, Sleep education and health education control
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 22, 2026, 10:03 AM EDT
Recruiting Not applicable Interventional

Empowering Youth With School Discipline Referrals as Peer Coaches

NCT07515742
View directory record Official record
Conditions
Disruptive Behavior
Interventions
Peer Coach Training (PCT), Delayed control
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
10 Years to 15 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 22, 2026, 10:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Network Intervention to Prevent Vaping

NCT04678245
View directory record Official record
Conditions
Vaping, Preventive Psychiatry, Social Networking
Interventions
Above the Influence-Vaping (ATI-V)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 18 Years
Enrollment
3,840 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Jul 22, 2026, 10:03 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Sleep Hygiene Intervention to Improve Sleep Quality in Urban, Latino Middle School Children - Phase 2

NCT03717246
View directory record Official record
Conditions
Sleep
Interventions
Sleep Smart Latino, Basic Sleep Hygiene and Child Health
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 5, 2021 · Synced Jul 22, 2026, 10:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer Based Newsletter and Literacy Engagement of Middle-school Students

NCT04511065
View directory record Official record
Conditions
Reading Problem
Interventions
Newsletter using a virtual mode of delivery
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 13 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Jul 22, 2026, 10:03 AM EDT