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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Middle Schools Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact

NCT01280136
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
It's Your Game Tech
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 16 Years
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

BullyDown, a Text Messaging-based Bullying Prevention Program for Middle School-aged Youth

NCT06017050
View directory record Official record
Conditions
Bullying
Interventions
BullyDown, Attention-matched control
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
12 Years to 14 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
San Clemente, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of the BE REAL Let's Eat Curriculum in Middle Schoolers

NCT07615088
View directory record Official record
Conditions
Eating Disorders in Children
Interventions
Let's Eat Nutrition Curriculum
Behavioral
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
11 Years to 14 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Middle and High School Students' Reactions to a Health Interactive Website: ASPIRE Reactions

NCT02469779
View directory record Official record
Conditions
Tobacco Use Cessation, Tobacco Prevention
Interventions
Surveys, ASPIRE Website, ASPIRE Text-Based Website, Follow Up Survey
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
11 Years to 18 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2021 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Virtual Reality Pain Neuroscience Education for Middle School Students

NCT04470375
View directory record Official record
Conditions
Pain, Education, Virtual Reality
Interventions
Virtual Reality Pain Neuroscience Education
Behavioral
Lead sponsor
University of South Dakota
Other
Eligibility
10 Years to 15 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Middle School to High School Transition Project: Depression and Substance Abuse Prevention

NCT00071513
View directory record Official record
Conditions
Depression, Substance-Related Disorders
Interventions
CAST-T/HSTS, Brief Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 15 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Results available

A Risky Sex Prevention Intervention for Middle School Age Minority Girls

NCT02103218
View directory record Official record
Conditions
HIV, Risky Sex Prevention
Interventions
Education, activities, empowerment, racial pride building, General Health education, activities
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
11 Years to 99 Years · Female only
Enrollment
212 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Generation Fit and Exerlearning With In the Groove"

NCT00424918
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity, reduced sedentary behavior
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
10 Years to 14 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Addition of Whole Grains to the Diets of Middle-school Children

NCT01094652
View directory record Official record
Conditions
Healthy
Interventions
Whole grain diet, Refined grain diet
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 15 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Tobacco Zero: Interactive Tobacco Education for Teens

NCT00670995
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Interactive Tobacco Education
Behavioral
Lead sponsor
Deschutes Research, Inc.
Other
Eligibility
11 Years to 15 Years
Enrollment
1,864 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 20, 2026, 2:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Preventing School Exclusion and Opioid Misuse: Effectiveness of the Inclusive Skill-building Learning Approach (ISLA)

NCT06292078
View directory record Official record
Conditions
Middle Schools, School Exclusion, School Community, Teaching Practices, Opioid and Other Substance Misuse
Interventions
Instructional Skill-Building Learning Approach (ISLA)
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
8 Years to 15 Years
Enrollment
5,076 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Capitola, California • Yuba City, California • Salem, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Bullying Bystander Intervention for Middle Schools Phase II

NCT05572398
View directory record Official record
Conditions
Adolescent, Bullying, Technology, Mental Health
Interventions
STAC-T
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
11 Years and older
Enrollment
613 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Boise, Idaho • University, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products

NCT03682900
View directory record Official record
Conditions
Tobacco Use
Interventions
Click City®: Tobacco, Usual Tobacco Curriculum
Other
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
9 Years to 12 Years
Enrollment
2,673 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 20, 2026, 2:37 AM EDT
Terminated Not applicable Interventional

Evaluating the Effectiveness of a Drug Education and Diversion Program for Middle and High School Students

NCT05321563
View directory record Official record
Conditions
Adolescent Behavior, Substance Use, Youth, Health Risk Behaviors
Interventions
iDECIDE (Drug Education Curriculum: Intervention, Diversion, and Empowerment)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
10 Years to 22 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Phase 2 Interventional

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

NCT01081119
View directory record Official record
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2014 · Synced Sep 20, 2026, 2:37 AM EDT
Recruiting Not applicable Interventional

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

NCT06587230
View directory record Official record
Conditions
Child Behavior, Mental Health Issue, Psychosocial Functioning, Depression, Anxiety
Interventions
Teachers Leading the Frontlines, Responding to Students' Emotions Through Education
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
5 Years to 99 Years
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Results available

Teaching Academic Success Skills to Students With Autism Spectrum Disorders in Clinical Setting

NCT03606343
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Teaching Academic Skills to Kids
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 14 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath

NCT04843501
View directory record Official record
Conditions
E-cigarette Use
Interventions
CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
10 Years to 15 Years
Enrollment
2,059 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Computer Based Newsletter and Literacy Engagement of Middle-school Students

NCT04511065
View directory record Official record
Conditions
Reading Problem
Interventions
Newsletter using a virtual mode of delivery
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 13 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2022 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional

Team Clinic: Virtual Expansion of an Innovative Multi-Disciplinary Care Model for Adolescents and Young Adults With Type 1 Diabetes

NCT04190368
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Team Clinic Care, Standard Care
Other
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
10 Years to 17 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Girls on the Move Intervention to Increase Physical Activity Among Middle School Girls

NCT01503333
View directory record Official record
Conditions
Physical Activity
Interventions
Physical activity intervention
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
9 Years to 14 Years · Female only
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Check-Up Online

NCT06161597
View directory record Official record
Conditions
Families of Middle School Students at Title 1 Schools
Interventions
Family Check-Up Online
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 16 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 20, 2026, 2:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Yoga for Substance Use Risk Factors in a School Setting

NCT01821950
View directory record Official record
Conditions
Adolescent Development
Interventions
Yoga during physical education
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
11 Years to 14 Years
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Sep 20, 2026, 2:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Peer Group Connection - Middle School

NCT06582641
View directory record Official record
Conditions
Teen Pregnancy Prevention
Interventions
Peer Group Connection - Middle School (PGC-MS)
Behavioral
Lead sponsor
The Policy & Research Group
Other
Eligibility
11 Years to 14 Years
Enrollment
1,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 20, 2026, 2:37 AM EDT