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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Middle Schools Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Neurological Influences on Drug Prevention Intervention

NCT00198939
View directory record Official record
Conditions
Youths At-risk for Drug Use/Abuse
Interventions
Integrated Family and Cognitive-Behavioral Drug Prevention Intervention, Psychoeducation
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
11 Years to 15 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2012 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation Processes in School-Based Substance Abuse Programs

NCT01755533
View directory record Official record
Conditions
Substance Use
Interventions
Rural curriculum, Classic curriculum
Other
Lead sponsor
Penn State University
Other
Eligibility
11 Years to 15 Years
Enrollment
2,827 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The TRAIN Study: A Concussion Prevention Strategy in Middle Schools

NCT04841473
View directory record Official record
Conditions
Concussion, Brain
Interventions
TRAIN Concussion Education, Standard Concussion Education
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

NCT04478240
View directory record Official record
Conditions
Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions
PeerLearning.net
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
Not listed
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Evaluation of an HIV, STD, and Pregnancy Prevention Program for Middle School Students

NCT00161382
View directory record Official record
Conditions
HIV Infections, Sexually Transmitted Diseases, Pregnancy
Interventions
HIV, STD, and pregnancy prevention curriculum, Standard sexual education curriculum
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
11 Years to 16 Years
Enrollment
3,007 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2014 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Middle School Physical Activity Intervention for Girls

NCT01351649
View directory record Official record
Conditions
Physical Activity
Interventions
middle school physical activity intervention for girls
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
10 Years to 14 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 17, 2015 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Expanding the Click City Tobacco Prevention Program to Include E-cigarettes and Other Novel Tobacco Products

NCT03682900
View directory record Official record
Conditions
Tobacco Use
Interventions
Click City®: Tobacco, Usual Tobacco Curriculum
Other
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
9 Years to 12 Years
Enrollment
2,673 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Springfield, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Bullying Bystander Intervention for Middle Schools Phase II

NCT05572398
View directory record Official record
Conditions
Adolescent, Bullying, Technology, Mental Health
Interventions
STAC-T
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
11 Years and older
Enrollment
613 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Boise, Idaho • University, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Middle School Parent Module for a Brief Bullying Intervention Program

NCT06002347
View directory record Official record
Conditions
Bullying
Interventions
STAC Parent Module for Middle School
Behavioral
Lead sponsor
Boise State University
Other
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Girls on the Move Intervention to Increase Physical Activity Among Middle School Girls

NCT01503333
View directory record Official record
Conditions
Physical Activity
Interventions
Physical activity intervention
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
9 Years to 14 Years · Female only
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
East Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 20, 2018 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Middle-School Based Primary Prevention Trial of Type 2 Diabetes

NCT00458029
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
integrated program of nutrition, activity, behavior, and promotion
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
10 Years to 16 Years
Enrollment
4,603 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
8
States / cities
Irvine, California • Rockville, Maryland • Chapel Hill, North Carolina + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Middle School Teacher Module for a Brief Bullying Intervention Program

NCT06017752
View directory record Official record
Conditions
Bullying
Interventions
STAC Teacher Module
Behavioral
Lead sponsor
Boise State University
Other
Eligibility
21 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Jul 22, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

NCT06587230
View directory record Official record
Conditions
Child Behavior, Mental Health Issue, Psychosocial Functioning, Depression, Anxiety
Interventions
Teachers Leading the Frontlines, Responding to Students' Emotions Through Education
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
5 Years to 99 Years
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Teachers and Parents as Partners During Middle School RCT

NCT03614026
View directory record Official record
Conditions
Behavior Disorders
Interventions
Teachers and Parents as Partners
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
10 Years to 17 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact

NCT01280136
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases
Interventions
It's Your Game Tech
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 16 Years
Enrollment
1,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

BullyDown, a Text Messaging-based Bullying Prevention Program for Middle School-aged Youth

NCT06017050
View directory record Official record
Conditions
Bullying
Interventions
BullyDown, Attention-matched control
Behavioral
Lead sponsor
Center for Innovative Public Health Research
Other
Eligibility
12 Years to 14 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
San Clemente, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 22, 2026, 4:57 PM EDT
Recruiting Not applicable Interventional

CSTOP Now! Child Sex Trafficking Stops With You

NCT05722769
View directory record Official record
Conditions
Child Sex Trafficking
Interventions
CSTOP Now!, Prevent Child Abuse Kentucky Online Training
Behavioral
Lead sponsor
Ann Coker
Other
Eligibility
21 Years to 65 Years
Enrollment
5,408 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Phase 2 Interventional

Brief Voluntary Alcohol and Drug Intervention for Middle School Youth

NCT01081119
View directory record Official record
Conditions
Alcohol Drinking, Cigarette Smoking, Marijuana Smoking
Interventions
Project CHOICE
Behavioral
Lead sponsor
RAND
Other
Eligibility
11 Years to 15 Years
Enrollment
6,455 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2014 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Evaluation of Spot Light: A Concussion Injury Management App for Youth Sports

NCT02249533
View directory record Official record
Conditions
TBI
Interventions
Spot Light Concussion App
Other
Lead sponsor
Lara McKenzie
Other
Eligibility
10 Years to 19 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training With Milk Supplementation in Adolescents

NCT01190592
View directory record Official record
Conditions
Body Composition, Cardiovascular Risk Factors
Interventions
Resistance Training with Milk Supplementation in Adolescents
Other
Lead sponsor
University of Kansas
Other
Eligibility
12 Years to 14 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 20, 2011 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Middle School to High School Transition Project: Depression and Substance Abuse Prevention

NCT00071513
View directory record Official record
Conditions
Depression, Substance-Related Disorders
Interventions
CAST-T/HSTS, Brief Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
12 Years to 15 Years
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional

Middle School Matters Study

NCT01220635
View directory record Official record
Conditions
Depression
Interventions
Positive Thoughts and Actions Program, Individual Support Program
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 13, 2014 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nudging for Behavior Change in School Cafeterias

NCT04156542
View directory record Official record
Conditions
Behavior, Child, Food Selection
Interventions
Basic School Lunchroom Nudges
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
10 Years to 15 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
6
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Jul 22, 2026, 4:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of the BE REAL Let's Eat Curriculum in Middle Schoolers

NCT07615088
View directory record Official record
Conditions
Eating Disorders in Children
Interventions
Let's Eat Nutrition Curriculum
Behavioral
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
11 Years to 14 Years
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 22, 2026, 4:57 PM EDT