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ClinicalTrials.gov public records Last synced Sep 8, 2026, 1:53 PM EDT

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Showing 1–24 of 94 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Mifepristone Clear all
Withdrawn No phase listed Observational

Breast Cancer BRCA1 Carriers: a Pilot Study

NCT05062174
View directory record Official record
Conditions
BRCA1 Mutation, High-grade Serous Ovarian Cancer, TNBC - Triple-Negative Breast Cancer
Interventions
Mifepristone 200 MG, Prophylactic mastectomy
Drug · Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Carmel, Indiana • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Sep 8, 2026, 1:53 PM EDT
Withdrawn Phase 3 Interventional

Mifepristone in Children With Refractory Cushing's Disease

NCT01925092
View directory record Official record
Conditions
Cushing's Disease
Interventions
mifepristone
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
6 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 3, 2014 · Synced Sep 8, 2026, 1:53 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

MiMi: A Randomized Trial of Mifepristone and Misoprostol for Treatment of Early Pregnancy Failure

NCT00468299
View directory record Official record
Conditions
Early Pregnancy Failure, Miscarriage, Fetal Demise, Anembryonic Pregnancy
Interventions
Misoprostol and placebo, Mifepristone and misoprostol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2011 · Synced Sep 8, 2026, 1:53 PM EDT
Terminated Not applicable Interventional Results available

Compassionate Use of Mifepristone in Brain/Nervous System and Other Cancers

NCT00832871
View directory record Official record
Conditions
Cancer
Interventions
Mifepristone
Drug
Lead sponsor
New Mexico Cancer Research Alliance
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mail Order Mifepristone Study

NCT03913104
View directory record Official record
Conditions
Abortion Early, Pregnancy Related
Interventions
Mifepristone
Drug
Lead sponsor
Daniel Grossman, MD
Other
Eligibility
15 Years and older · Female only
Enrollment
536 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
11
States / cities
Oakland, California • Denver, Colorado • Wilmington, Delaware + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2024 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Phase I Study to Determine the Effect of Mifepristone on the Pharmacokinetics of Fluvastatin in Healthy Volunteers

NCT00752843
View directory record Official record
Conditions
Healthy Subjects
Interventions
mifepristone + fluvastatin
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 16, 2012 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 3 Interventional

A United States Extension Study of Corlux for Recurrent Psychotic Symptoms in Psychotic Major Depression

NCT00208156
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Mifepristone
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
13
States / cities
San Diego, California • Atlanta, Georgia • Las Vegas, Nevada + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 3 Interventional Results available

Mifepristone Versus Osmotic Dilator Insertion for Cervical Preparation Prior to Surgical Abortion at 15-18 Weeks

NCT01436279
View directory record Official record
Conditions
Cervical Preparation
Interventions
Mifepristone, osmotic dilators
Drug · Device
Lead sponsor
Boston University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 3 Interventional

A United States Study of the Safety and Tolerability of Corlux for Psychotic Symptoms in Psychotic Major Depression

NCT00128479
View directory record Official record
Conditions
Major Depressive Disorder, Psychotic Disorders
Interventions
mifepristone, mifepristone matched placebo, mifepristone 600 mg, mifepristone 1200 mg
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
443 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
44
States / cities
Little Rock, Arkansas • Cerritos, California • Fountain Valley, California + 40 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Sep 8, 2026, 1:53 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location

NCT05839899
View directory record Official record
Conditions
Abortion
Interventions
Mifepristone plus one dose Misoprostol, Mifepristone plus two doses Misoprostol
Drug
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Not applicable Interventional Results available

Mifepristone in Refractory Depression

NCT00186056
View directory record Official record
Conditions
Depression
Interventions
Mifepristone, Placebo Oral Tablet
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 8, 2026, 1:53 PM EDT
Terminated Phase 2 Interventional

Study of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer

NCT02642939
View directory record Official record
Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
Mifepristone
Drug
Lead sponsor
Check, Jerome H., M.D., Ph.D.
Individual
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Melrose Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Sep 8, 2026, 1:53 PM EDT
Not listed Phase 2 Interventional

Trial of Mifepristone in Combat Veterans With Posttraumatic Stress Disorder

NCT00833339
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
mifepristone, placebo
Drug
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older · Male only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Sep 8, 2026, 1:53 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Mifepristone vs. Placebo in the Treatment of Patients With Major Depression With Psychotic Features

NCT00637494
View directory record Official record
Conditions
Psychotic Depression, Severe Major Depression With Psychotic Features, Psychosis
Interventions
mifepristone, placebo
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
22 Years and older
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
42
States / cities
Little Rock, Arkansas • Anaheim, California • Downey, California + 34 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2017 · Synced Sep 8, 2026, 1:53 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Cervical Preparation With Mifepristone Prior to Osmotic Dilators

NCT03714880
View directory record Official record
Conditions
Second Trimester Abortion
Interventions
Mifepristone 200 MG, Placebo Oral Tablet
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2022 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 2 Interventional

Mifepristone for Patients With Endometrial Cancer and LGESS

NCT00505739
View directory record Official record
Conditions
Endometrial Cancer
Interventions
Mifepristone
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2012 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 2 Interventional Results available

Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men

NCT01294319
View directory record Official record
Conditions
Cortisol Resistance, Negative Feedback, ACTH, Mineralcorticoid, Glucocorticoid
Interventions
Mifepristone, Placebo, Spironolactone, Combined, Dexamethasone
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 80 Years · Male only
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2024 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Not applicable Interventional

Patient Agreement Form and Medication Abortion Knowledge

NCT07604675
View directory record Official record
Conditions
Medication Abortion, Health Knowledge Attitudes and Practice, Pregnant People
Interventions
Patient Agreement Form (PAF)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years and older · Female only
Enrollment
637 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
5
States / cities
San Francisco, California • Denver, Colorado • Carbondale, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 8, 2026, 1:53 PM EDT
Completed No phase listed Observational

Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation

NCT01966874
View directory record Official record
Conditions
Medical; Abortion, Fetus
Interventions
Not listed
Lead sponsor
Gynuity Health Projects
Other
Eligibility
Female only
Enrollment
1,001 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2013 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 3 Interventional Results available

An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome

NCT00936741
View directory record Official record
Conditions
Cushing's Syndrome
Interventions
mifepristone
Drug
Lead sponsor
Corcept Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
15
States / cities
Birmingham, Alabama • Escondido, California • Stanford, California + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2014 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older Individuals

NCT01988610
View directory record Official record
Conditions
Depression
Interventions
28 days treatment with Mifepristone.
Drug
Lead sponsor
Stanford University
Other
Eligibility
50 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 2 Interventional

Mifepristone (RU-486) in Androgen Independent Prostate Cancer

NCT00140478
View directory record Official record
Conditions
Prostate Cancer, Adenocarcinoma of Prostate
Interventions
Mifepristone
Drug
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 8, 2009 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Mifepristone at Same Time Multicenter Study

NCT00269568
View directory record Official record
Conditions
Abortion Seekers
Interventions
mifepristone and misoprostol
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
1,128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
4
States / cities
Los Angeles, California • Chicago, Illinois • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Sep 8, 2026, 1:53 PM EDT
Completed Phase 1 Interventional

A Clinical Trial for Post Traumatic Stress Disorder

NCT00554177
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD)
Interventions
Medicane (mifepristone), Placebo
Drug
Lead sponsor
Antonia New
Other
Eligibility
18 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 16, 2016 · Synced Sep 8, 2026, 1:53 PM EDT