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ClinicalTrials.gov public records Last synced Jul 22, 2026, 10:21 AM EDT

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Showing 1–24 of 175 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Minimally Invasive Surgery Clear all
Recruiting No phase listed Observational

Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia

NCT07016620
View directory record Official record
Conditions
Benign Prostatic Hyperplasia (BPH)
Interventions
Transperineal Laser Ablation (TPLA)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Male only
Enrollment
20 participants
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

Evaluation of the Safety, Effectiveness & Usability of the XACT Robotic System for Image Guided Percutaneous Procedures

NCT03008603
View directory record Official record
Conditions
CT-guided Minimally Invasive Procedures e.g., Biopsies
Interventions
XACT Robotic System
Device
Lead sponsor
Xact Robotics Ltd.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Jul 22, 2026, 10:21 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Multimodal Analgesia Versus Routine Care Pain Management

NCT01861743
View directory record Official record
Conditions
Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
Interventions
Multimodal Analgesia, Patient controlled analgesia
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Results available

Bariatric Embolization of Arteries for the Treatment of Obesity

NCT02165124
View directory record Official record
Conditions
Morbid Obesity
Interventions
Artificial Embolization Device
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 4, 2018 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational

Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation

NCT00571597
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Results available

Minimally Invasive Surgical Treatment Versus Medical Management for Stroke Patients With Atrial Fibrillation

NCT01442181
View directory record Official record
Conditions
Atrial Fibrillation, Stroke
Interventions
Minimally Invasive Surgery, Medical therapy
Procedure · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting Phase 3 Interventional

Minimally Invasive Surgery After Neoadjuvant Chemotherapy for the Treatment of Stage IIIC-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer, LANCE Trial

NCT04575935
View directory record Official record
Conditions
Advanced Ovarian Carcinoma, Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Tumor, Fallopian Tube Serous Neoplasm, Fallopian Tube Transitional Cell Carcinoma, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Serous Adenocarcinoma, Ovarian Transitional Cell Carcinoma, Primary Peritoneal Clear Cell Adenocarcinoma, Primary Peritoneal Endometrioid Adenocarcinoma, Primary Peritoneal Serous Adenocarcinoma, Primary Peritoneal Transitional Cell Carcinoma, Stage IIIC Fallopian Tube Cancer AJCC v8, Stage IIIC Ovarian Cancer AJCC v8, Stage IIIC Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8, Stage IVA Fallopian Tube Cancer AJCC v8, Stage IVA Ovarian Cancer AJCC v8, Stage IVA Primary Peritoneal Cancer AJCC v8, Stage IVB Fallopian Tube Cancer AJCC v8, Stage IVB Ovarian Cancer AJCC v8, Stage IVB Primary Peritoneal Cancer AJCC v8
Interventions
Chemotherapy, Laparotomy, Minimally Invasive Surgery, Quality-of-Life Assessment, Questionnaire Administration
Drug · Procedure · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
13
States / cities
Miami, Florida • Weston, Florida • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Phase 3 Interventional Results available

Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III

NCT01827046
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
rt-PA
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
499 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
56
States / cities
Birmingham, Alabama • Phoenix, Arizona • Carmichael, California + 46 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Not listed Phase 1Phase 2 Interventional

Postoperative Pain Control With Lipossomic Extended Release Bupivacaine

NCT03560362
View directory record Official record
Conditions
Pain, Postoperative, Lung Cancer
Interventions
Bupivacaine liposome, Bupivacaine / Epinephrine
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

Minimally Invasive Surgical Approaches In Total Knee Arthroplasty

NCT01461356
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Minimally invasive total knee replacement, Standard approach total knee replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 27, 2011 · Synced Jul 22, 2026, 10:21 AM EDT
Enrolling by invitation No phase listed Observational

Three Year Outcomes of Combined Hydrus Microstent With iTrack Canaloplasty

NCT07073937
View directory record Official record
Conditions
Glaucoma, Open Angle, MIGS, Minimally Invasive Glaucoma Surgery, Canaloplasty, Intraocular Pressure (IOP), Cataract Surgery, Surgical Technique, Minimally Invasive Surgical Technique, Glaucoma
Interventions
Retrospective chart review
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

GATT-Patch Versus SURGICEL® Original in Minimally Invasive Liver and Gallbladder Surgery

NCT05900037
View directory record Official record
Conditions
Intraoperative Bleeding, Liver Diseases, Gallbladder Diseases, Hemorrhage, Surgical
Interventions
GATT-Patch, SURGICEL® Original
Device
Lead sponsor
GATT Technologies BV
Industry
Eligibility
22 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
6
States / cities
Los Angeles, California • St Louis, Missouri • Pennington, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed No phase listed Observational Results available

Patient Factors Associated With Fragmentation of Copper Intrauterine Device (IUD) Requiring Hysteroscopic Removal

NCT07351084
View directory record Official record
Conditions
Intrauterine Device Complications, Contraceptive Device Failure, IUD Fragmentation, Retained Intrauterine Device, Female Contraception, Women's Health, Reproductive Health
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
44 participants
Timeline
2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Phase 2 Interventional Results available

Botulinum Toxin Type A in Preventing Complications After Surgery in Patients With Esophageal Cancer

NCT02965976
View directory record Official record
Conditions
Esophageal Carcinoma
Interventions
Botulinum Toxin Type A, Esophagectomy, Quality-of-Life Assessment
Biological · Procedure · Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Phase 1Phase 2 Interventional

Dose-escalation Study of a Contrast Agent for Delineation of Urological Anatomy in Minimally Invasive Surgery

NCT03106038
View directory record Official record
Conditions
Intraoperative Ureter Injury
Interventions
Nerindocianine for Injection
Drug
Lead sponsor
Li-Cor, Inc.
Industry
Eligibility
19 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting Not applicable Interventional

Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery

NCT06731998
View directory record Official record
Conditions
Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer, Gastric (Cardia, Body) Cancer, Biliary Tract Cancer, Pancreatic Cancer Resectable, Gynecologic Cancers, Gastrointestinal Cancers, Colorectal Cancer, Minimally Invasive Surgical Procedures
Interventions
Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
Procedure
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 22, 2026, 10:21 AM EDT
Withdrawn Phase 2 Interventional

Open-label Study to Evaluate Nerindocianine as a Surgical Aid in Ureter Delineation During Minimally Invasive Surgery

NCT04636567
View directory record Official record
Conditions
Intraoperative Ureter Injury
Interventions
Nerindocianine for injection
Drug
Lead sponsor
Li-Cor, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
2
States / cities
Weston, Florida • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional

Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyroidism

NCT03011736
View directory record Official record
Conditions
Parathyroid Gland Adenoma, Primary Hyperparathyroidism
Interventions
Laboratory Biomarker Analysis, Parathyroidectomy
Other · Procedure
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Jul 22, 2026, 10:21 AM EDT
Recruiting No phase listed Observational

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

NCT04885244
View directory record Official record
Conditions
Adult Spinal Deformity, Scoliosis, Kyphosis, Sagittal Imbalance
Interventions
Index or spine revision surgery for complex adult spinal deformity
Procedure
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2034
U.S. locations
12
States / cities
Phoenix, Arizona • La Jolla, California • Los Angeles, California + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Active, not recruiting Not applicable Interventional

AFFIX: Post-market Study of MaxTack™ Motorized Fixation Device in Subjects Undergoing Ventral Hernia Repair

NCT06710795
View directory record Official record
Conditions
Ventral Hernia
Interventions
MaxTack™ Motorized Fixation Device
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Weston, Florida • Cleveland, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Laparoscopic Transversus Abdominis Plane (TAP) Block to Reduce Post-operative Opioids

NCT04655339
View directory record Official record
Conditions
Opioid Use
Interventions
Bilateral abdominal Lap-TAP
Drug
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 22, 2026, 10:21 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Minimally Invasive Closure of Umbilical Hernias

NCT00706329
View directory record Official record
Conditions
Umbilical Hernia
Interventions
Deflux
Device
Lead sponsor
South Shore Hospital
Other
Eligibility
1 Year to 5 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
South Weymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Emdogain Minimally Invasive Surgical Technique

NCT02551770
View directory record Official record
Conditions
Periodontitis
Interventions
Scaling and root planing, Scaling and root planing without Emdogain, Emdogain application
Procedure · Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
21 Years to 85 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
2
States / cities
Cullman, Alabama • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 16, 2019 · Synced Jul 22, 2026, 10:21 AM EDT
Completed Phase 2 Interventional Results available

A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery

NCT04238481
View directory record Official record
Conditions
Laparoscopic/Minimally Invasive Colorectal Surgery
Interventions
Pudexacianinium chloride
Drug
Lead sponsor
Astellas Pharma Inc
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Orlando, Florida • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Jul 22, 2026, 10:21 AM EDT