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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:01 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 137 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Mood Management Clear all

Conditions: Recruitment
Interventions: Healthy Mood Project Website; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 1,226 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alcoholism, Smoking
Interventions: nicotine replacement patch, mood management; Drug · Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2003
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Bipolar Depression
Interventions: CoEnzyme Q10; Drug
Lead sponsor: Mclean Hospital; Other
Eligibility: 55 Years to 89 Years
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Belmont, Massachusetts

Conditions: Major Depressive Disorder
Interventions: Pathway Platform mobile app; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Depressive Disorder, Major, Suicidal Ideation
Interventions: Ketamine; Drug
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Depression
Interventions: Collaborative depression care management, Enhanced usual care; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 387 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Depression, Major Depressive Disorder
Interventions: Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR); Drug
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer; Industry
Eligibility: 7 Years to 17 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 9
States / cities: Little Rock, Arkansas • North Miami, Florida • Terre Haute, Indiana + 6 more

Conditions: Postpartum Depression
Interventions: ZULRESSO®; Drug
Lead sponsor: Supernus Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 52 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 6
States / cities: Culver City, California • Miramar, Florida • Pompano Beach, Florida + 2 more

Conditions: Epilepsy, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depression
Interventions: TIME; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Mood Change, Depressive Symptoms, Anxiety Generalized
Interventions: Integrative-Mind-Body Skills Group; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: White Plains, New York

Conditions: Depression, Depressive Disorder, Behavioral Symptoms, Mood Disorders
Interventions: Collaborative depression care management; Behavioral
Lead sponsor: University of Southern California; Other
Eligibility: 18 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Mood
Interventions: Activities., Wait list; Behavioral · Other
Lead sponsor: i4Health; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Depression
Interventions: Nurse-led case management, Treatment as usual; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 80 Years
Enrollment: 214 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Mood Disturbance, Mood Disorders, Natural Supplements, Alternative Treatment
Interventions: Open-label Treatment with Omega-3 Fatty Acids + Inositol, Open-label Treatment with N-acetylcysteine; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 5 Years to 17 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Coronary Syndrome, Tobacco Use
Interventions: Experimental: Behavioral Activation Treatment for Cardiac Smokers (BAT-CS), Smoking cessation plus Health and Wellness; Behavioral
Lead sponsor: The Miriam Hospital; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery, Exercise and Recovery, Exercise Training, Anxiety and Mood Disorders, Sleep, Motivation, Comfort, Pain Management, Rehabilitation, Creativity and Mindfulness
Interventions: soundBrilliance software application - Emotional Health; Device
Lead sponsor: soundBrilliance LLC; Industry
Eligibility: 13 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Fort Collins, Colorado • Omaha, Nebraska • Reno, Nevada

Conditions: Bipolar Disorder
Interventions: Experimental Diet, Comparator Diet; Other
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Health Behavior, Quality of Life, Aging
Interventions: Not listed
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 110 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Depression
Interventions: Visbiome, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 15 Years to 24 Years
Enrollment: 77 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, Postpartum Depression
Interventions: Mothers and babies Internet course and PPD informational brochure; Behavioral
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 1,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Bipolar Depression
Interventions: ceftriaxone, Saline solution; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Multiple Sclerosis, Major Depressive Disorder
Interventions: POWER-MS, FLEX-MS; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years to 64 Years
Enrollment: 146 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Depression, Obesity
Interventions: RAINBOW Intervention Program; Behavioral
Lead sponsor: Palo Alto Medical Foundation; Other
Eligibility: 18 Years and older
Enrollment: 409 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 2
States / cities: Palo Alto, California • Stanford, California

Conditions: Bipolar Disorder, Major Depressive Disorder, Schizo Affective Disorder
Interventions: Lamictal; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Healthy Mood Internet Recruitment Study

Behavioral Counseling for Alcohol Dependent Smokers (Nicotine Patch)

CoQ10 in Geriatric Bipolar Depression

Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression

Ketamine for Mood Disorders With Suicidal Ideation

Collaborative Depression Care Management in Treating Depressed Low-income Hispanics With Diabetes

Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Child And Adolescent Outpatients With Major Depressive Disorder

A Study To Assess The Safe-Use Conditions For Administration of ZULRESSO® in a Home Setting

Targeted Self-Management for Epilepsy and Serious Mental Illness (TIME)

Mind-Body Skills Group for Graduate Students

Multifaceted Depression and Cardiovascular Program

Mood Management Effects of Brief Unsupported Internet Interventions II

Nurse-led Case Management for Diabetes and Cardiovascular Disease Patients With Depression

A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth

Integrated Smoking Cessation and Mood Management for ACS Patients

The Impact of Enhanced Music & Natural Visuals on Emotional Health

Dietary Intervention for Bipolar Disorder

The Lake Nona Life Project

Probiotic Administration for Adolescent Depression

Effectiveness of a Web-based Prevention Program for Postpartum Depression

Ceftriaxone in the Management of Bipolar Depression

Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

Research Aimed at Improving Both Mood and Weight

A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women