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ClinicalTrials.gov public records Last synced Nov 3, 2026, 10:06 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 553–576 of 747 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Motility Disorders Clear all
Recruiting No phase listed Observational

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

NCT04770519
View directory record Official record
Conditions
Strabismus, Nystagmus, Congenital
Interventions
whole genome sequencing or whole exome sequencing
Genetic
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Nov 3, 2026, 10:06 PM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tri Staple Technology Stapler Used in Gastric Bypass

NCT01026103
View directory record Official record
Conditions
Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease, Gastroesophageal Reflux Disease, Osteoarthritis, Diabetes
Interventions
Tri Staple Technology stapler
Device
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Nov 3, 2026, 10:06 PM EST
Completed Not applicable Interventional Results available

Convergence Insufficiency Treatment Study (CITS)

NCT01515943
View directory record Official record
Conditions
Convergence Insufficiency
Interventions
Active home-based computer vergence/accommodative therapy, Near target push-ups, Placebo home-based computer vergence/accommodative therapy, Placebo yoked prism flippers
Other · Procedure
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
9 Years to 17 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Cranberry TWP, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Natural History of Gastroesophageal Reflux (GER) in Children < 12 Years of Age

NCT01048840
View directory record Official record
Conditions
Gastroesophageal Reflux
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational

Quality of Life After Esophagectomy for Cancer

NCT00798746
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Telephone Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced Nov 3, 2026, 10:06 PM EST
Completed Not applicable Interventional

Mic-Key Versus Mini One Family Preference Comparison

NCT03041649
View directory record Official record
Conditions
Gastroesophageal Reflux, Feeding Disorder, Family Satisfaction
Interventions
GT button change - Mic-Key, GT button change - Mini One
Other
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 5 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Nov 3, 2026, 10:06 PM EST
Completed Phase 2 Interventional

A Study to Evaluate the Efficacy and Safety of Arbaclofen Placarbil (XP19986) as Adjunctive Therapy in Subjects With Gastroesophageal Reflux Disease (GERD)

NCT00978016
View directory record Official record
Conditions
Gastroesophageal Reflux Disease
Interventions
arbaclofen placarbil-Cohort 1, Placebo-Cohort 5, arbaclofen placarbil-Cohort 2, arbaclofen placarbil-Cohort 3, arbaclofen placarbil-Cohort 4, PPI
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
62
States / cities
Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Nov 3, 2026, 10:06 PM EST
Not listed Phase 3 Interventional Accepts healthy volunteers

Office-based Vision Therapy for Improving Reading and Attention in Children With Convergence Insufficiency

NCT02207517
View directory record Official record
Conditions
Convergence Insufficiency
Interventions
Office-based vergence/accommodative therapy
Procedure
Lead sponsor
Salus University
Other
Eligibility
9 Years to 13 Years
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
8
States / cities
Birmingham, Alabama • Fullerton, California • Fort Lauderdale, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational

Mechanisms of Weight Loss in Patients Diagnosed With Achalasia

NCT03063463
View directory record Official record
Conditions
Achalasia
Interventions
pneumatic dilation, surgical myotomy
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Nov 3, 2026, 10:06 PM EST
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetics of Pantoprazole and CYP2C19 Activity in Children and Adolescents With GERD: A Pilot Study

NCT01887743
View directory record Official record
Conditions
Obesity, GERD
Interventions
Pantoprazole
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
6 Years to 17 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Relationship and Pathophysiology of Gastroesophageal Reflux and Dental/Periodontal Disease

NCT01167543
View directory record Official record
Conditions
Gastroesophageal Reflux, Dental Erosion
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Years to 18 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2010 · Synced Nov 3, 2026, 10:06 PM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.

NCT03349515
View directory record Official record
Conditions
Strabismus
Interventions
Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
1 Year to 17 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 16, 2019 · Synced Nov 3, 2026, 10:06 PM EST
Not listed Not applicable Interventional

Novel Endoluminal Clinical TreAtment of Reflux

NCT03090607
View directory record Official record
Conditions
GERD
Interventions
Aluvra™, Saline
Device · Drug
Lead sponsor
Impleo Medical Inc.
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
10
States / cities
Los Angeles, California • Palo Alto, California • Englewood, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced Nov 3, 2026, 10:06 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Confocal Endomicroscopy for Permeability of Esophageal Wall in Refractory Gastroesophageal Reflux Disease (GERD)

NCT03228407
View directory record Official record
Conditions
Gastro Esophageal Reflux, Barrett Esophagus, Erosive Esophagitis
Interventions
Confocal endomicroscopy, Endoscopic biopsies, Mucosal impedance (MI)
Procedure · Diagnostic Test
Lead sponsor
McGuire Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Nov 3, 2026, 10:06 PM EST
Completed Phase 4 Interventional

Treatment of Disturbed Sleep in Progressive Supranuclear Palsy (PSP)

NCT04014387
View directory record Official record
Conditions
Progressive Supranuclear Palsy(PSP), Insomnia
Interventions
Suvorexant, Zolpidem, Placebo oral capsule
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Nov 3, 2026, 10:06 PM EST
Completed Phase 1 Interventional

Do Acid Sensing Ion Channels Contribute to Heartburn?

NCT01095133
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Heartburn
Interventions
Amiloride, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 59 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 20, 2012 · Synced Nov 3, 2026, 10:06 PM EST
Terminated No phase listed Observational

Gastroesophageal Reflux Disease Prospective Registry

NCT02479438
View directory record Official record
Conditions
GERD
Interventions
Diagnosed with GERD
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
744 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational

Esophageal Motility in Reflux Induced Cough

NCT02492126
View directory record Official record
Conditions
Cough
Interventions
Citric Acid
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Oct 30, 2020 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational

Epidemiology of Barrett's Esophagus: A Population Based Study

NCT01286155
View directory record Official record
Conditions
Barrett's Esophagus, Gastroesophageal Reflux Disease (GERD), Olmsted County Resident
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 95 Years
Enrollment
534 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Nov 3, 2026, 10:06 PM EST
Recruiting No phase listed Observational

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

NCT07293689
View directory record Official record
Conditions
Type III Achalasia, EGJ Outflow Obstruction With Spastic/Hypercontractile Features, Jackhammer Esophagus, Distal Esophageal Spasm
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
16
States / cities
Scottsdale, Arizona • La Jolla, California • Denver, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Acid Reflux at Two Levels in the Esophagus Using the BRAVO Capsule

NCT00579410
View directory record Official record
Conditions
Esophagitis, Inflammation, Gastritis, Abdominal Pain, Heartburn
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 22, 2011 · Synced Nov 3, 2026, 10:06 PM EST
Completed No phase listed Observational

Speech Accessibility Project

NCT05889260
View directory record Official record
Conditions
Parkinson Disease, Progressive Supranuclear Palsy, Multiple System Atrophy, Dementia With Lewy Bodies
Interventions
Not listed
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Denver, Colorado • Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Nov 3, 2026, 10:06 PM EST
Not listed Phase 2 Interventional

Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia

NCT01302288
View directory record Official record
Conditions
Achalasia
Interventions
Per oral endolumenal myotomy
Procedure
Lead sponsor
The Oregon Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 28, 2011 · Synced Nov 3, 2026, 10:06 PM EST
Recruiting Phase 2 Interventional

Fosamprenavir for Laryngopharyngeal Upper Airway Tissue Treatment and Enzyme Reduction

NCT04383262
View directory record Official record
Conditions
Laryngopharyngeal Reflux
Interventions
Fosamprenavir Calcium, Placebo
Drug · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 64 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Nov 3, 2026, 10:06 PM EST