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Conditions: Stroke, Brain Disease, Central Nervous System Diseases, Nervous System Diseases, Cardiovascular Diseases
Interventions: Deep Brain Stimulation (DBS) of the Motor Thalamus; Device
Lead sponsor: Jorge Gonzalez-Martinez; Other
Eligibility: 18 Years to 75 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Stuttering, Developmental, Aphasia, Primary Progressive
Interventions: Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords, Anodal tDCS, Sham tDCS, Learning of non-native phoneme combinations: 8 training sessions; Behavioral · Device
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 6 Years and older
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Boston, Massachusetts • Ann Arbor, Michigan

Conditions: Developmental Verbal Dyspraxia, Autism Spectrum Disorder
Interventions: CAS Treatment for Minimally Verbal Children with Autism; Behavioral
Lead sponsor: MGH Institute of Health Professions; Other
Eligibility: 5 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stuttering, Developmental, Dyslexia, Healthy Participants
Interventions: Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation, Sustained F0 auditory feedback perturbation, Reflexive somatosensory perturbation, Anodal tCS targeting pSTG and vSSC, Anodal tCS targeting left or right vPMC, Sham tCS targeting pSTG or vSSC, Sham tCS targeting left vPMC or right vPMC; Behavioral · Other
Lead sponsor: Boston University Charles River Campus; Other
Eligibility: 18 Years to 50 Years
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 2
States / cities: Boston, Massachusetts

Conditions: ALS (Amyotrophic Lateral Sclerosis), ALS - Amyotrophic Lateral Sclerosis
Interventions: Isometric Lingual Strength Exercises; Procedure
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Davie, Florida

Conditions: Autism Spectrum Disorder, Apraxia of Speech
Interventions: Video Assisted Speech Therapy (VAST); Behavioral
Lead sponsor: iTherapy, LLC; Other
Eligibility: 4 Years to 8 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Vallejo, California

Conditions: Dysarthria, Intelligibility, Speech
Interventions: Perceptual Training; Behavioral
Lead sponsor: Utah State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 217 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 2
States / cities: Tallahassee, Florida • Logan, Utah

Conditions: Speech Sound Disorder
Interventions: Speech Motor Chaining; Behavioral
Lead sponsor: Syracuse University; Other
Eligibility: 9 Years to 17 Years
Enrollment: 84 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Syracuse, New York

Conditions: Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia Non Fluent
Interventions: Low-intensity physical exercise, High-intensity physical exercise; Behavioral
Lead sponsor: University of California, Berkeley; Other
Eligibility: 18 Years to 80 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 4
States / cities: Berkeley, California • Hayward, California • San Francisco, California

Conditions: Stroke, Aphasia, Reading Disorder
Interventions: Phono-Motor Therapy, Aerobic Exercise Training (AET), Stretching; Behavioral
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years to 85 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Speech Sound Disorder
Interventions: Traditional articulation treatment, Visual-acoustic biofeedback; Behavioral
Lead sponsor: New York University; Other
Eligibility: 8 Years to 15 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Amyotrophic Lateral Sclerosis, Parkinson Disease
Interventions: Phonetic complexity effects on speech motor performance; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 19 Years to 90 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2022
U.S. locations: 2
States / cities: Fairway, Kansas • Columbia, Missouri

Conditions: Amyotrophic Lateral Sclerosis
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Stroke
Interventions: fluoxetine, placebo; Drug
Lead sponsor: Spaulding Rehabilitation Hospital; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
Interventions: transcranial alternating current stimulation (tACS); Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Speech Sound Disorder
Interventions: Visual-acoustic biofeedback, Ultrasound biofeedback; Behavioral
Lead sponsor: New York University; Other
Eligibility: 9 Years to 15 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 3
States / cities: Bloomfield, New Jersey • New York, New York • Syracuse, New York

Conditions: Stutter, Stuttering, Adult, Stuttering, Stuttering, Developmental
Interventions: Speech Production During functional magnetic resonance imaging (MRI); Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Developmental Stuttering
Interventions: Not listed
Lead sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Cerebral Palsy (CP), Dysarthria
Interventions: Speech only, Hand/Arm only, Speech and arm combined; Behavioral
Lead sponsor: Rutgers, The State University of New Jersey; Other
Eligibility: 8 Years to 17 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Newark, New Jersey

Conditions: Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, Apraxia, Motor, Dysarthria, Communication Disorders, Language Disorders, Speech Disorders, Neurocognitive Disorders, Aphasia, Bilingual Aphasia
Interventions: Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT); Behavioral
Lead sponsor: Stephanie Grasso; Other
Eligibility: 40 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis, Cervical Spinal Cord Injury, Dysarthria
Interventions: Connexus Brain-Computer Interface; Device
Lead sponsor: Paradromics; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2032
U.S. locations: 3
States / cities: Sacramento, California • Boston, Massachusetts • Ann Arbor, Michigan

Conditions: Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury, Speech Disorders
Interventions: Speech generating device (SGD) evaluation including BCI access, Training and treatment; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 14 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 2
States / cities: Carnegie, Pennsylvania • Pittsburgh, Pennsylvania

Conditions: Amyotrophic Lateral Sclerosis, Lou Gehrig's Disease, ALS
Interventions: Not listed
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis, Progressive Muscular Atrophy
Interventions: Digital Speech and Handwriting Assessment; Behavioral
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Search by objective public record fields.

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech

Speech Treatment for Minimally Verbal Children With ASD and CAS

Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech

Tongue-strengthening Exercises in People With ALS.

Video Assisted Speech Technology to Enhance Motor Planning for Speech

Perceptual Training to Improve Listeners' Ability to Understand Speech Produced by Individuals With Dysarthria

Intensive Speech Motor Chaining Treatment for Residual Speech Sound Disorders

Effects of High-intensity Exercise Training on Physical Fitness, Cognition, Language in Post-stroke Aphasia

Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

staRt: Enhancing Speech Treatment With Smartphone-delivered Biofeedback

A Systematic Investigation of Phonetic Complexity Effects on Articulatory Motor Performance in Progressive Dysarthria

DESIPHER_Speech Degradation as an Indicator of Physiological Degeneration in ALS

Fluoxetine for Motor, Aphasia, and Neglect Recovery After Ischemic Stroke

Transcranial Alternating Current Stimulation (tACS) in Stuttering

Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors

Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering

Dopamine Function in Developmental Stuttering

Speech and Arm Combined Exergame

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

Real World Testing of a Brain-Computer Interface

Digital Speech Markers for Monitoring ALS in Spanish Speakers

Digital Assessment of Speech and Fine Motor Control in ALS