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ClinicalTrials.gov public records Last synced Oct 23, 2026, 5:46 PM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle Anabolism Clear all
Completed No phase listed Observational Accepts healthy volunteers Results available

Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement

NCT01325792
View directory record Official record
Conditions
Ventral Incisional Hernia
Interventions
GORE® BIO-A® Tissue Reinforcement
Device
Lead sponsor
W.L.Gore & Associates
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
8
States / cities
San Diego, California • Indianapolis, Indiana • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2015 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Insect-derived Protein Supplements on Protein Synthesis and mTORC1 Activation

NCT05457218
View directory record Official record
Conditions
Effect of Food Supplement
Interventions
Whey protein, IPC80, Whole Buffalo Powder
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Anabolic Action of Plant-based Foods Using Complementary Proteins

NCT06781723
View directory record Official record
Conditions
Health, Recreational Activities, Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Interventions
Resistance Exercise, Isolated Mixture, Rice and Beans
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Defining Beef and Meal Frequency as Key Components of a Healthy Eating Pattern for Muscle Health and Wellbeing

NCT04232254
View directory record Official record
Conditions
Meal Frequency, Dietary Habits, Muscle Protein Synthesis
Interventions
Animal-based Protein Foods, Skewed Protein Distribution, Plant-based Protein Foods, Balanced Protein Distribution
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 23, 2026, 5:46 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

CO as a Stimulant for Mitochondrial Biogenesis in Human Cardiac Muscle

NCT01727167
View directory record Official record
Conditions
Cardiac Disease, Mitochondrial Biogenesis, Carbon Monoxide
Interventions
200ppm CO for one hour, Control
Drug · Other
Lead sponsor
John J Freiberger
Other
Eligibility
20 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2016 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Time Course of Postprandial Protein Metabolism

NCT04121689
View directory record Official record
Conditions
Muscle Protein Synthesis, Protein Metabolism
Interventions
Milk Protein Concentrate
Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 10, 2019 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults

NCT03870165
View directory record Official record
Conditions
Hypertrophy
Interventions
Resistance exercise, Salmon, Isolated amino acids and fatty acids
Behavioral · Other · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults

NCT01489930
View directory record Official record
Conditions
Sarcopenia
Interventions
Endurance exercise, Resistance exercise, Control/Combined training
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 12, 2011 · Synced Oct 23, 2026, 5:46 PM EDT
Terminated Phase 1Phase 2 Interventional

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy

NCT01847573
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
HT-100
Drug
Lead sponsor
Processa Pharmaceuticals
Industry
Eligibility
6 Years to 20 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Sacramento, California • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Oct 23, 2026, 5:46 PM EDT
Not yet recruiting Phase 2 Interventional

HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide

NCT07760948
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Obesity, Muscle Loss, Older Adults
Interventions
Calcium-HMB Plus Vitamin D3, Matching placebo
Dietary Supplement · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
65 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Meal-based Comparison of Protein Quality, Complementary Proteins and Muscle Anabolism

NCT03816579
View directory record Official record
Conditions
Protein, Diet, Skeletal Muscle
Interventions
PRO-A, PRO-B, PRO-C
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
45 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Essential Amino Acids Supplementation and Muscle Protein Synthesis

NCT01366924
View directory record Official record
Conditions
Muscle Loss, Muscle Anabolism
Interventions
Essential Amino Acids, Endurance exercise
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Boston, Massachusetts • Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skeletal Muscle Protein Synthetic Response to Amino Acid and Peptides

NCT03952884
View directory record Official record
Conditions
Protein Metabolism
Interventions
Resistance Exercise, No Resistance Exercise, Leucine, Dileucine
Behavioral · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2020 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Essential Amino Acids and Protein Kinetics During Caloric Deprivation

NCT03372928
View directory record Official record
Conditions
Muscle Protein Synthesis, Whole-body Protein Balance
Interventions
Standard EAA, High EAA
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function

NCT01671514
View directory record Official record
Conditions
Heart Failure, Type 2 Diabetes
Interventions
Epicatechin-enriched dark chocolate, Low-epicatechin dark chocolate
Dietary Supplement · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 23, 2026, 5:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Muscle Response to Different Amounts of Dietary Protein During Leg Immobilization

NCT07069426
View directory record Official record
Conditions
Muscle Disuse, Muscle Disuse Atrophy
Interventions
20 grams protein, 40 grams protein
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 23, 2026, 5:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Muscle Protein Synthesis in Dialysis Patients

NCT03478722
View directory record Official record
Conditions
Muscle Loss
Interventions
Protein Meal, Stable Isotope Amino Acid Infusion
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Protein Synthesis After Whole Egg vs. Egg White Consumption

NCT03117127
View directory record Official record
Conditions
Hypertrophy
Interventions
Resistance Exercise, Whole Eggs, Egg Whites
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2018 · Synced Oct 23, 2026, 5:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Diet Synergy in Muscle Protein Synthesis

NCT07367854
View directory record Official record
Conditions
Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism, Recreational Activities, Isotope Labeling
Interventions
Resistance Exercise, Potato and Beef, Bread and Beef, Beef
Behavioral · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults

NCT04015479
View directory record Official record
Conditions
Aging, Sarcopenia
Interventions
Peanut Protein Powder, Full body resistance training
Dietary Supplement · Behavioral
Lead sponsor
Auburn University
Other
Eligibility
50 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 12, 2021 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Phase 1 Interventional

Gene Expression and Tolerability Study of NV1FGF in Patients With Peripheral Artery Occlusive Disease Planned to Undergo Major Amputation

NCT01157143
View directory record Official record
Conditions
Peripheral Arterial Occlusive Disease
Interventions
XRP0038 (NV1FGF)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 5, 2010 · Synced Oct 23, 2026, 5:46 PM EDT
Recruiting Not applicable Interventional

Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults

NCT06025292
View directory record Official record
Conditions
Hyperglycaemia (Non Diabetic), Prediabetes
Interventions
Lean Pork vs Plant-Based Protein
Other
Lead sponsor
University of Arkansas
Other
Eligibility
40 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults

NCT05593978
View directory record Official record
Conditions
Sarcopenia
Interventions
Culinary Medicine, Control
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
65 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Aug 4, 2023 · Synced Oct 23, 2026, 5:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Blends (Soy, Whey and Casein) for Muscle Synthesis

NCT01358305
View directory record Official record
Conditions
Muscle Synthesis
Interventions
Protein Blend
Other
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 23, 2026, 5:46 PM EDT