- Conditions
- Cerebral Palsy, Muscle Spasticity
- Interventions
- Botulinum toxin type A
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 3 Years to 12 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 1997
- U.S. locations
- 1
- States / cities
- Seattle, Washington
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Showing 25–48
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- Conditions
- Inflammation; Muscle
- Interventions
- ESPO-572®, PCSO-524®
- Dietary Supplement
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 30 Years · Male only
- Enrollment
- 57 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Bloomington, Indiana
- Conditions
- Muscle Damage, Muscle Strength, Muscle Weakness
- Interventions
- Treatment with BTL-899M, Treatment with BTL-899M with intensities below therapeutic threshold
- Device
- Lead sponsor
- BTL Industries Ltd.
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 3
- States / cities
- Scottsdale, Arizona • Greenwood Village, Colorado • Palm Beach Gardens, Florida
- Conditions
- Cerebral Palsy, Spastic
- Interventions
- Vibration Platform, Placebo Platform
- Device
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 5 Years to 11 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Interventions
- Botulinum toxin type A, Placebo
- Biological · Drug
- Lead sponsor
- Ipsen
- Industry
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 241 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 8
- States / cities
- Aurora, Colorado • Chicago, Illinois • New Orleans, Louisiana + 5 more
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
- Interventions
- Neurosleeve
- Device
- Lead sponsor
- Thomas Jefferson University
- Other
- Eligibility
- 4 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2026
- U.S. locations
- 2
- States / cities
- Wilmington, Delaware • Philadelphia, Pennsylvania
- Conditions
- Muscle Spasticity
- Interventions
- Baclofen bolus injection
- Drug
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Spastic Cerebral Palsy
- Interventions
- Self Hypnosis, Acupuncture, Osteopathic Manipulation
- Procedure
- Lead sponsor
- National Center for Complementary and Integrative Health (NCCIH)
- NIH
- Eligibility
- 4 Years to 21 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1998 – 2004
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Muscle Damage, Muscle
- Interventions
- Placebo control capsules, PeptiStrong® supplement capsules with same appearance as placebo capsules, PeptiStrong® supplement capsules following muscle damaging exercise on Day 14
- Other
- Lead sponsor
- PepsiCo Global R&D
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Bradenton, Florida
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness, Immune Function, Gut Health, Microbiome Analysis, Exercise Performance, Exercise Metabolism
- Interventions
- Postbiotic Active Lifestyle Blend, Placebo
- Dietary Supplement · Other
- Lead sponsor
- Lindenwood University
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Saint Charles, Missouri
- Conditions
- Cerebral Palsy, Muscle Hypertonia
- Interventions
- Not listed
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 6 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2005
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
- Interventions
- Botulinum Toxin Type A
- Biological
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 220 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 24
- States / cities
- Pasadena, California • Pomona, California • San Diego, California + 19 more
- Conditions
- Cerebral Palsy
- Interventions
- HMB + Vitamin D3
- Dietary Supplement
- Lead sponsor
- Gillette Children's Specialty Healthcare
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 7 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Saint Paul, Minnesota
- Conditions
- Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
- Interventions
- Self-Supporting Nasopharyngeal Airway (ssNPA)
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 3 Years to 23 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Cerebral Palsy, Weakness, Hypertonia
- Interventions
- surface EMG biofeedback
- Device
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 1 Month to 21 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2007
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Cerebral Palsy Spastic Diplegia
- Interventions
- Short Burst Interval Locomotor Treadmill Training (SBLTT)
- Behavioral
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 5 Years to 12 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Muscle Spasticity, Hypertonia, Muscle, Cerebral Palsy, Multiple Sclerosis, Stroke, Hereditary Spastic Paraplegia, Dystonia, Spinal Cord Injuries
- Interventions
- MTR-601
- Drug
- Lead sponsor
- Motric Bio
- Industry
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 89 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Cerebral Palsy, Myelomeningocele, Arthrogryposis, Motor Skills Disorders, Gross Motor Development Delay
- Interventions
- adapted Chicago Run running program
- Behavioral
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Chicago Heights, Illinois
- Conditions
- Muscle Damage
- Interventions
- Control Unmodified Placebo Water, Electrokinetically modified water (EMW)
- Dietary Supplement
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2017
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cerebral Palsy
- Interventions
- SPIO® Core-MAX® Expedition thoracolumbosacral orthosis, Standard Care Therapy option
- Device · Other
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 6 Months to 18 Months
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Muscular Injury
- Interventions
- NUTRALYS pea protein supplement, Whey Protein, Apple juice
- Dietary Supplement
- Lead sponsor
- Appalachian State University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Kannapolis, North Carolina
- Conditions
- Muscle Damage
- Interventions
- Solarplast (R), Placebo
- Dietary Supplement
- Lead sponsor
- Kent State University
- Other
- Eligibility
- 18 Years to 35 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Kent, Ohio
- Conditions
- Soreness, Muscle, Performance Enhancing Product Use, Damage Muscle
- Interventions
- Pre-workout plus and protein recovery plus, Placebo
- Dietary Supplement · Other
- Lead sponsor
- Pharmanex
- Industry
- Eligibility
- 25 Years to 50 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
- Interventions
- EA-KAFO
- Device
- Lead sponsor
- National Institutes of Health Clinical Center (CC)
- NIH
- Eligibility
- 3 Years to 17 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland