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ClinicalTrials.gov public records Last synced Nov 14, 2026, 7:20 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 206 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: NAC Clear all

Conditions: Breast Cancer
Interventions: Molecular Breast Imaging (MBI), Tc99m sestamibi; Procedure · Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Type 1 Diabetes, Hypoglycemia Unawareness
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 65 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Parkinson Disease, Idiopathic Parkinson Disease
Interventions: N acetyl cysteine, [F-18] Fluorodopa Positron Emission Tomography; Dietary Supplement · Drug
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 30 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Lower Respiratory Infection, SARS-CoV2 Infection, SARS-CoV-2 Acute Respiratory Disease, SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere, Oxidative Stress
Interventions: N-acetylcysteine, Placebo; Drug · Other
Lead sponsor: Cambridge Health Alliance; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Everett, Massachusetts

Conditions: Hepatitis C
Interventions: N-acetylcysteine(Mucomyst); Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Retinitis Pigmentosa
Interventions: N-acetylcysteine, Placebo; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 485 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 24
States / cities: Davis, California • Los Angeles, California • San Francisco, California + 21 more

Conditions: COPD, Chronic Bronchitis
Interventions: N-Acetylcysteine, Placebo; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 40 Years to 85 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Biliary Atresia
Interventions: N-Acetyl cysteine; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 0 Days to 90 Days
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Subjective Memory Loss in Older Persons
Interventions: Cerefolin NAC (a medical food), Cerefolin NAC placebo; Other
Lead sponsor: Rush University Medical Center; Other
Eligibility: 60 Years and older
Enrollment: 104 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Pruritus, Skin Disorder
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: Wright State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Fairborn, Ohio

Conditions: Early Memory Loss, Mild Cognitive Impairment, Alzheimer's Disease, Vascular Dementia
Interventions: CerefolinNAC®; Other
Lead sponsor: Pamlab, Inc.; Industry
Eligibility: 50 Years to 80 Years
Enrollment: 204 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Hickory, North Carolina

Conditions: Schizophrenia, Cognitive Deficits, Schizophrenia; Negative Type
Interventions: N-acetylcysteine, Treatment as Usual; Drug · Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Cannabis Dependence
Interventions: N-Acetylcysteine; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 12 Years to 20 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Asthma
Interventions: n-acetylcystine, 0.9% saline; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 70 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Hangover Symptoms, NAC
Interventions: N Acetyl Cysteine, placebo; Dietary Supplement · Other
Lead sponsor: St. Luke's Hospital and Health Network, Pennsylvania; Other
Eligibility: 21 Years and older
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Parkinson Disease, Idiopathic Parkinson Disease
Interventions: Intravenous and Oral n-acetyl cysteine, Control group, Oral Supplements: Baicalin, Ganoderma, Omega 3 and Curcumin; Dietary Supplement · Other
Lead sponsor: Thomas Jefferson University; Other
Eligibility: 30 Years to 80 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Idiopathic Pulmonary Fibrosis
Interventions: N-acetyl cysteine, Placebo; Drug
Lead sponsor: Fernando J Martinez; Other
Eligibility: 40 Years and older
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2026
U.S. locations: 25
States / cities: Tucson, Arizona • Los Angeles, California • Stanford, California + 22 more

Conditions: Nephropathy
Interventions: intravenous NAC, Placebo; Drug
Lead sponsor: Ochsner Health System; Other
Eligibility: 18 Years and older
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: New Orleans, Louisiana

Conditions: Stages II-III Breast Cancer
Interventions: Nanoparticle Albumin Bound Paclitaxel, doxorubicin, cyclophosphamide; Drug
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older · Female only
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2017
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Healthy
Interventions: Delta-9-THC, N-acetylcysteine, Placebo; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Liver Failure, Liver Failure, Acute, Drug Induced Liver Injury, Prevention & Control, Fever
Interventions: APAP and NAC combination, APAP and Placebo; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2009
U.S. locations: 1
States / cities: New York, New York

Conditions: Neurofibromatosis 1
Interventions: N-Acetyl cysteine, Placebo; Drug · Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 8 Years to 16 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Bipolar Disorder, Depression
Interventions: N-acetyl cysteine (NAC); Drug
Lead sponsor: Martin Lan; Other
Eligibility: 18 Years to 60 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: New York, New York

Conditions: Pilon Fracture
Interventions: N-acetylcysteine, Saline; Drug
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2026
U.S. locations: 1
States / cities: Columbia, Missouri

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Tc99m Sestamibi Molecular Breast Imaging

A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes

FDOPA PET and Nutritional Support in Parkinson's Disease

NAC for Attenuation of COVID-19 Symptomatology

Mucomyst for Hepatitis C

Oral N-acetylcysteine for Retinitis Pigmentosa

N-Acetylcysteine for Patients With COPD and Chronic Bronchitis

N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy

Study of the Effects of Cerefolin NAC on Inflammation Blood Markers in Older Individuals With Memory Complaints

Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli

NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)

Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine

An Open-Label Trial of N-Acetylcysteine in Cannabis Dependent Adolescents

Clinical Trial of NAC in Asthma

Use of NAC in Alleviation of Hangover Symptoms

Physiological Effects of Nutritional Support in Patients With Parkinson's Disease

Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial

Effect of Intravenous Acetadote on Incidence of Contrast Induced Nephropathy

Study of Neoadjuvant Chemotherapy With Nanoparticle Albumin Bound Paclitaxel, Doxorubicin and Cyclophosphamide (NAC) in Patients With Stages II-III Breast Cancer

N-acetylcysteine Effects on Tetrahydrocannabinol

Acetaminophen in Combination With N-Acetylcysteine (NAC) Versus Placebo in Treating Fever

Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1

Brain Imaging to Understand the Role of Inflammation in N-Acetyl Cysteine (NAC) Treatment of Bipolar Depression

Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)