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ClinicalTrials.gov public records Last synced Oct 7, 2026, 10:46 AM EDT

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Showing 97–120 of 171 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neck Pain Treatment Clear all
Recruiting Not applicable Interventional

Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural Populations

NCT07179016
View directory record Official record
Conditions
Chronic Pain (Back / Neck), Chronic Pain Management, Chronic Knee Pain, Joint Pain
Interventions
Auricular Point Acupressure (APA) - Self Management (SM), Education Control
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 85 Years
Enrollment
693 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
3
States / cities
Columbia, South Carolina • Fort Worth, Texas • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Terminated Phase 3 Interventional Results available

Perioperative Analgesia Using Gabapentin in Head and Neck Cancer Surgery

NCT03682367
View directory record Official record
Conditions
Cancer of Head and Neck, Narcotic Use
Interventions
Gabapentin, Placebo - Concentrate
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2021 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 4 Interventional Results available

Gabapentin for Pain Control After Osmotic Dilator Insertion and Prior to D&E Procedure: a Randomized Controlled Trial

NCT03080493
View directory record Official record
Conditions
Abortion, Induced, Cervical Preparation, Pain
Interventions
Gabapentin 600mg, Placebo oral capsule, acetaminophen/codeine and ibuprofen
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older · Female only
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2020 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Early Phase 1 Interventional

Pilot Trial of Microsphere Oxycodone (Xtampza ER) for Pain Management in Patients Receiving Radiotherapy for Locally Advanced Head and Neck Cancer

NCT03317730
View directory record Official record
Conditions
Locally Advanced Head and Neck Cancer
Interventions
Xtampza ER
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 20, 2021 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Results available

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

NCT02205801
View directory record Official record
Conditions
Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease, Hyperparathyroidism
Interventions
Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline, Marcaine
Procedure · Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 3 Interventional

Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer

NCT00090337
View directory record Official record
Conditions
Head and Neck Cancer, Pain
Interventions
acupuncture therapy, standard follow-up care
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
Not listed
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2013 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 2 Interventional

Chiropractic and Exercise for Seniors With Neck Pain

NCT00269308
View directory record Official record
Conditions
Neck Pain
Interventions
Chiropractic Manual treatment + home exercise ( procedure+behavior), Supervised rehabilitative exercise + home exercise, Home exercise
Procedure · Behavioral
Lead sponsor
Northwestern Health Sciences University
Other
Eligibility
65 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2011 · Synced Oct 7, 2026, 10:46 AM EDT
Terminated Phase 3 Interventional

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

NCT04176419
View directory record Official record
Conditions
Postoperative Pain Control, Opioid Consumption
Interventions
Ketamine, Placebo Ketamine, Lidocaine, Placebo Lidocaine, Acetaminophen, Placebo Acetaminophen, Gabapentin, Placebo Gabapentin, Celecoxib, Placebo Celecoxib
Drug
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 7, 2026, 10:46 AM EDT
Not listed Phase 4 Interventional

Study on Magnetic Field Therapy to Improve Quality of Sleep and Reduction of Chronic Spine Pain

NCT00445133
View directory record Official record
Conditions
Back Pain, Neck Pain, Sleep Initiation and Maintenance Disorders
Interventions
Magnetic Sleep Pad
Device
Lead sponsor
Weintraub, Michael I., MD, FACP, FAAN
Individual
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Briarcliff Manor, New York
Source: ClinicalTrials.gov public record
Updated Sep 27, 2007 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 2 Interventional Results available

Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps

NCT03349034
View directory record Official record
Conditions
Head and Neck Cancer, Free Tissue Transfer
Interventions
Ropivicaine, Local Saline Infusion
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2020 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 3 Interventional Results available

A Two Part Study (306A/306B) to Assess Droxidopa in Treatment of NOH in Patients With Parkinson's Disease

NCT01176240
View directory record Official record
Conditions
Orthostatic Hypotension, Parkinson's Disease
Interventions
Droxidopa, Placebo
Drug · Other
Lead sponsor
Chelsea Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
60
States / cities
Alabaster, Alabama • Gilbert, Arizona • Phoenix, Arizona + 53 more
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional

Effects of Cervical Manual Therapy on Cervicogenic Headache

NCT03385889
View directory record Official record
Conditions
Unilateral Headache, Musculoskeletal Neck Pain
Interventions
Cervical Spine Mobilization, Cervical Spine Manipulation
Procedure
Lead sponsor
Shenandoah University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Winchester, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional

Superficial Cervical Plexus Block for IJCL Pain Management

NCT05252832
View directory record Official record
Conditions
Superficial Cervical Plexus Block, Pain
Interventions
Superficial Cervical Plexus Block, Local Infiltrate
Procedure
Lead sponsor
Cleveland Clinic Akron General
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Osteopathic Manipulative Treatment on Neuromuscular Control of the Head-neck System

NCT02261259
View directory record Official record
Conditions
Neck Pain
Interventions
Osteopathic manipulative treatment
Procedure
Lead sponsor
Michigan State University
Other
Eligibility
21 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
East Lansing, Michigan • Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 4, 2019 · Synced Oct 7, 2026, 10:46 AM EDT
Not yet recruiting Not applicable Interventional

Musical Mindfulness for Pain in the ED Waiting Room

NCT07391891
View directory record Official record
Conditions
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
Interventions
Music intervention
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Active, not recruiting Not applicable Interventional

Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance

NCT06275074
View directory record Official record
Conditions
Neck Pain, Sleep Disturbance
Interventions
Dry Needling, Therapeutic Exercise
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Recruiting Not applicable Interventional

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

NCT04693377
View directory record Official record
Conditions
Castration-Resistant Prostate Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Prostate Carcinoma, Metastatic Renal Cell Carcinoma, Metastatic Sarcoma, Metastatic Thyroid Gland Carcinoma, Metastatic Urothelial Carcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8
Interventions
Cryosurgery, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy
Procedure · Other · Radiation
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional

Pain Management for Head and Neck Cancer Survivors

NCT05115825
View directory record Official record
Conditions
Head and Neck Carcinoma
Interventions
Behavioral Intervention, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Terminated Not applicable Interventional

Evaluating Different Low-level Laser Therapies to Treat Neck Pain in Air Force Pilots and Flight Crew

NCT03945240
View directory record Official record
Conditions
Neck Pain
Interventions
Group 1 -- using Pinnacle Series Laser Device, Group 2 -- using Pinnacle Series Laser Device, Group 3 -- using Phoenix Thera-Lase Device
Procedure
Lead sponsor
Paul Crawford
Federal
Eligibility
18 Years to 62 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

ATI Evidence-based Guide Investigating Clinical Services

NCT02285868
View directory record Official record
Conditions
Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle, Hip, Elbow, Neurological, Vestibular, Pelvic Floor, TMJ, Fibromyalgia, Headaches, Lymphedema
Interventions
Not listed
Lead sponsor
ATI Holdings, LLC
Industry
Eligibility
Not listed
Enrollment
4,000,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Not applicable Interventional

Noxipoint Therapy Versus Standard Physical Therapy Using Electrical Stimulation for Chronic Pain

NCT01578148
View directory record Official record
Conditions
Shoulder Pain, Neck Pain
Interventions
Noxipoint Therapy, Physical Therapy
Procedure
Lead sponsor
Pain Cure Center, California
Industry
Eligibility
18 Years to 64 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 4 Interventional Results available

Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion

NCT04254081
View directory record Official record
Conditions
Procedural Pain, Buprenorphine, Adjuvants, Anesthesia, Dilation and Evacuation, Analgesics
Interventions
Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 7, 2026, 10:46 AM EDT
Completed No phase listed Observational

Central Sensitization in Patients Seeking Outpatient Physical Therapy Services

NCT05467592
View directory record Official record
Conditions
Low Back Pain, Knee Osteoarthritis, Neck Pain
Interventions
Standard Physical Therapy care
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
77 participants
Timeline
2022 – 2024
U.S. locations
1
States / cities
Shawnee Mission, Kansas
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Oct 7, 2026, 10:46 AM EDT
Completed Phase 2 Interventional

Cervical Mobilization vs. Standard Physical Therapy for Chronic Neck Pain

NCT01092715
View directory record Official record
Conditions
Neck Pain
Interventions
Spinal mobilization, Massage, Neck exercises
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 25, 2010 · Synced Oct 7, 2026, 10:46 AM EDT