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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Nephrolithiasis Clear all
Completed Not applicable Interventional Results available

ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi

NCT03959683
View directory record Official record
Conditions
Kidney Calculi
Interventions
Trilogy Lithotrite, The ShockPulse-SE Lithotripsy System
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Phoenix, Arizona • Indianapolis, Indiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Jul 23, 2026, 2:09 PM EDT
Recruiting Early Phase 1 Interventional

Fecal Microbiota Transplantation in Kidney Stone Patients

NCT05516472
View directory record Official record
Conditions
Kidney Stones
Interventions
Microbial Transplant Therapy, Placebo
Drug
Lead sponsor
Joshua Stern
Other
Eligibility
18 Years to 69 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Park City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 9, 2025 · Synced Jul 23, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Results available

Clinical Evaluation of BackStop in Patients Undergoing Ureteroscopic Lithotripsy

NCT02122341
View directory record Official record
Conditions
Kidney Stones
Interventions
BackStop
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Los Angeles, California • Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Phase 4 Interventional

Effectiveness of Urinary Alkalinizing Agents on Kidney Stone Risk

NCT04095975
View directory record Official record
Conditions
Kidney Stone
Interventions
Baking Soda, LithoLyte
Dietary Supplement
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 21, 2021 · Synced Jul 23, 2026, 2:09 PM EDT
Not listed Phase 2Phase 3 Interventional

ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study

NCT02155803
View directory record Official record
Conditions
Sarcoidosis, Hypercalcemia Due to Sarcoidosis
Interventions
ACTHAR Gel (adrenocorticotropic hormone)
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2015 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Phase 2 Interventional Results available

Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria

NCT02289755
View directory record Official record
Conditions
Hyperoxaluria, Nephrolithiasis
Interventions
ALLN-177
Drug
Lead sponsor
Allena Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Indianapolis, Indiana • Lake Success, New York • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Phase 2 Interventional

Study of ALLN-177 in Patients Aged 12 Years or Older With Enteric or Primary Hyperoxaluria and Hyperoxalemia

NCT03391804
View directory record Official record
Conditions
Enteric Hyperoxaluria, Primary Hyperoxaluria, Hyperoxalemia
Interventions
ALLN-177
Drug
Lead sponsor
Allena Pharmaceuticals
Industry
Eligibility
12 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • New Haven, Connecticut + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 29, 2020 · Synced Jul 23, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

NCT06346483
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
Dusting without Moses 2.0 Modulation, Dusting with Moses 2.0 Modulation, Moses 2.0 Modulation
Procedure · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Intrarenal Pressure in Suctioning vs. Non-suctioning Sheaths

NCT07619456
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Suctioning-UAS, Non-suctioning-UAS
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 23, 2026, 2:09 PM EDT
Recruiting No phase listed Observational

Rare Kidney Stone Consortium Biobank

NCT02026388
View directory record Official record
Conditions
Primary Hyperoxaluria, Dent Disease, APRT Deficiency, Cystinuria
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2030
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Jul 23, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG)

NCT06721975
View directory record Official record
Conditions
Kidney Stones, Nephrolithiasis
Interventions
Thulio pulsed Thulium:YAG (p-Tm:YAG), Thulium Laser Fiber (TFL)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 23, 2026, 2:09 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy

NCT03043027
View directory record Official record
Conditions
Renal Calculi, Postoperative Pain
Interventions
liposomal bupivicaine, Bupivacaine, Saline Solution
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2017 · Synced Jul 23, 2026, 2:09 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Oxalate Formation From Ascorbic Acid

NCT04603898
View directory record Official record
Conditions
Kidney Stone
Interventions
Low Oxalate Diet, Carbon-13 Ascorbic Acid Oral Load
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis

NCT02938884
View directory record Official record
Conditions
Nephrolithiasis, Low Urine Volume
Interventions
HidrateSpark Water Bottle
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 100 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Scottsdale, Arizona • Chicago, Illinois • Bloomington, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Phase 2 Interventional Results available

Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones

NCT01077284
View directory record Official record
Conditions
Hyperuricosuria, Kidney Stones
Interventions
Febuxostat, Allopurinol, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
28
States / cities
Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 25 more
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Jul 23, 2026, 2:09 PM EDT
Completed No phase listed Observational

Brushite Kidney Stones: A Registry and Database of Clinical and Laboratory Findings

NCT00169663
View directory record Official record
Conditions
Nephrolithiasis
Interventions
Not listed
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 23, 2012 · Synced Jul 23, 2026, 2:09 PM EDT
Completed No phase listed Observational

"Dusting" Versus "Basketing" - Treatment Of Intrarenal Stones

NCT01619735
View directory record Official record
Conditions
Kidney Calculi, Kidney Stones, Nephrolithiasis, Renal Stones
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
8
States / cities
Scottsdale, Arizona • San Diego, California • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Jul 23, 2026, 2:09 PM EDT
Terminated Phase 2 Interventional

Efficacy and Safety of Using MPC-5971 in Subjects Undergoing Shock Wave Lithotripsy

NCT00860093
View directory record Official record
Conditions
Nephrolithiasis
Interventions
placebo, MPC-5971
Other · Drug
Lead sponsor
Mission Pharmacal
Industry
Eligibility
18 Years to 70 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
3
States / cities
Meridian, Idaho • Columbus, Ohio • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Jul 23, 2026, 2:09 PM EDT
Terminated Not applicable Interventional Results available

MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy

NCT03995758
View directory record Official record
Conditions
Kidney Calculi
Interventions
MOSES
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones

NCT03526458
View directory record Official record
Conditions
Stone Ureter, Stone;Renal, Surgery
Interventions
Holmium:YAG laser
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 19, 2021 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Quality of Life in Kidney Stone Patients Undergoing Surgery

NCT02625051
View directory record Official record
Conditions
Kidney Calculi, Quality of Life
Interventions
Ureteroscopy, Percutaneous nephrolithotomy
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jul 23, 2026, 2:09 PM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

Safety, Tolerability, and Pharmacodynamics of NOV-001 in Adult Subjects

NCT04909723
View directory record Official record
Conditions
Healthy Volunteers, Enteric Hyperoxaluria
Interventions
NOV-001, NB1000S, NB2000P, Placebo
Combination Product · Biological · Drug
Lead sponsor
Novome Biotechnologies Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
19
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Daytona Beach, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Jul 23, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Access Sheath and Stent Trial

NCT07297953
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
Surveys
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 23, 2026, 2:09 PM EDT
Completed Not applicable Interventional

High Powered Stone Dusting vs. Fragmentation and Basketing at Time of Ureteroscopy

NCT05006937
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
Dusting, Basket extraction
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Jul 23, 2026, 2:09 PM EDT