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ClinicalTrials.gov public records Last synced Oct 23, 2026, 7:36 PM EDT

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Showing 289–312 of 569 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Neurodevelopmental Conditions Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties

NCT05133479
View directory record Official record
Conditions
Language Disorders in Children
Interventions
Let's Know! small-group or TierL 2 Intervention
Behavioral
Lead sponsor
MGH Institute of Health Professions
Other
Eligibility
5 Years to 12 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting Not applicable Interventional

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

NCT04432883
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active Comparator: Experimental: Active cathodal tDCS + language training, Sham Comparator: Placebo cathodal tDCS + Speech and language
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
25 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Completed No phase listed Observational

Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene

NCT03892798
View directory record Official record
Conditions
Autism Spectrum Disorder, Movement Disorders, Seizures, Dystonia, NEDAMSS
Interventions
No interventions are planned
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
2 Months to 80 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Phase 4 Interventional Results available

Comparison of Keppra and Clonidine in the Treatment of Tics

NCT00370838
View directory record Official record
Conditions
Tic Disorders, Tourette Syndrome
Interventions
Levetiracetam, Clonidine
Drug
Lead sponsor
Harvey S. Singer
Other
Eligibility
7 Years to 19 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 7, 2011 · Synced Oct 23, 2026, 7:36 PM EDT
Withdrawn Early Phase 1 Interventional

Relapse Prevention in Stimulant Use Disorder

NCT04553263
View directory record Official record
Conditions
Stimulant Use, Relapse, Cognitive Function, ADHD
Interventions
Contrave 8Mg-90Mg Extended-Release Tablet, Bupropion
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2023 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Not applicable Interventional

iPad Application to Treat Prosodic Deficits in Students With Communication Disorders

NCT01917864
View directory record Official record
Conditions
Autism, Communication Disorders
Interventions
iPad Application
Behavioral
Lead sponsor
Yale University
Other
Eligibility
4 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 14, 2016 · Synced Oct 23, 2026, 7:36 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Parent and Infant Inter(X)Action Intervention (PIXI)

NCT03836300
View directory record Official record
Conditions
Fragile X Syndrome, Angelman Syndrome, Prader-Willi Syndrome, Dup15Q Syndrome, Duchenne Muscular Dystrophy, Phelan-McDermid Syndrome, Rett Syndrome, Smith Magenis Syndrome, Williams Syndrome, Turner Syndrome, Klinefelter Syndrome, Chromosome 22q11.2 Deletion Syndrome, Tuberous Sclerosis, Down Syndrome
Interventions
Parent-Infant Inter(X)action Intervention (PIXI)
Behavioral
Lead sponsor
RTI International
Other
Eligibility
Up to 99 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Research Triangle Park, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Completed No phase listed Observational

Prevalence of Spasticity in Adults With Mental Retardation Living in the Community

NCT00282191
View directory record Official record
Conditions
Mental Retardation, Spasticity
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Davidson County, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 28, 2008 · Synced Oct 23, 2026, 7:36 PM EDT
Not yet recruiting Phase 4 Interventional

Semaglutide in Youth With Autism Spectrum Disorder

NCT07770152
View directory record Official record
Conditions
Autism Spectrum Disorder, Obesity
Interventions
Glucagon-like peptide-1 receptor agonist：Semaglutide, Lifestyle Management (LSM) Counseling
Drug · Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting Not applicable Interventional

Telerehabilitation for Aphasia (TERRA)

NCT04682223
View directory record Official record
Conditions
Aphasia, Stroke, Stroke Rehabilitation
Interventions
Semantically-focused therapy tasks, Phonologically-focused therapy tasks
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
21 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Active, not recruiting Phase 3 Interventional

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

NCT06660394
View directory record Official record
Conditions
Dravet Syndrome
Interventions
LP352, Placebo
Drug
Lead sponsor
Longboard Pharmaceuticals
Industry
Eligibility
2 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
25
States / cities
Little Rock, Arkansas • Los Angeles, California • Palo Alto, California + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Phase 2 Interventional Results available

A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome

NCT03569631
View directory record Official record
Conditions
Fragile X Syndrome, FXS, Fra(X) Syndrome
Interventions
BPN14770, Placebo
Drug
Lead sponsor
Tetra Discovery Partners
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Not applicable Interventional

Randomized Study of Fluoxetine in Children and Adolescents With Autism

NCT00004486
View directory record Official record
Conditions
Autism
Interventions
fluoxetine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
5 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2002
U.S. locations
3
States / cities
New York, New York • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 25, 2015 · Synced Oct 23, 2026, 7:36 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing the Impact of Peer Support vs. Staff-Delivered Transportation Interventions for Young Adults With Intellectual and Developmental Disabilities.

NCT07505121
View directory record Official record
Conditions
Intellectual Disability, Mild to Moderate, Developmental Disability
Interventions
Ready to Ride - Standard Delivery, Ready to Ride - Peer Support Delivery
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 27 Years
Enrollment
325 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Gainesville, Florida • Minneapolis, Minnesota • Durham, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting Phase 4 Interventional

Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities

NCT06997198
View directory record Official record
Conditions
Tardive Dyskinesia, Intellectual Disability, Developmental Disabilities
Interventions
Deutetrabenazine Oral Capsule
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting Not applicable Interventional

Harnessing Communication Preferences

NCT07278544
View directory record Official record
Conditions
Intellectual Disability, Autism Spectrum Disorder, Self-Injurious Behavior, Communication Disabilities, Communication, Nonverbal
Interventions
PrefFCT, NonPrefFCT
Behavioral
Lead sponsor
Joel E. Ringdahl
Other
Eligibility
2 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
Athens, Georgia • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience Among Surrogate Decision-Makers of ICU Patients

NCT03276559
View directory record Official record
Conditions
Critical Illness, Communication Disabilities
Interventions
EMPOWER, Enhanced Usual Care
Behavioral · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
3
States / cities
Flushing, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced Oct 23, 2026, 7:36 PM EDT
Completed No phase listed Observational

Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years

NCT03561168
View directory record Official record
Conditions
Seizures, Development Delay, Anesthetic Neurotoxicity
Interventions
Change in plan of care based on MRI results
Diagnostic Test
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 1095 Days
Enrollment
561 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 19, 2018 · Synced Oct 23, 2026, 7:36 PM EDT
Completed Phase 1Phase 2 Interventional

Animal Assisted Therapy in a Pediatric Setting

NCT01441674
View directory record Official record
Conditions
Developmental Delays, Global Developmental Delay, Stroke, Cancers, Seizures Disorders, Behavior Problems, Feeding Disorder, Developmental Delay in Feeding
Interventions
Animal Assisted Therapy
Behavioral
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 14, 2014 · Synced Oct 23, 2026, 7:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

NCT00001246
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Schizophrenia, Attention Deficit Disorder With Hyperactivity
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
3 Years to 120 Years
Enrollment
4,274 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 1990
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Completed No phase listed Observational

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

NCT03426059
View directory record Official record
Conditions
Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
Interventions
No Intervention
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
22 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
6
States / cities
Stanford, California • Chicago, Illinois • Bethesda, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

SenseToKnow Autism Screening Device Validation Study

NCT05874466
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
16 Months to 36 Months
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

NCT05473429
View directory record Official record
Conditions
Intellectual Disability
Interventions
TSA2 Thermosensory Stimulator
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
8 Years to 30 Years
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Oct 23, 2026, 7:36 PM EDT
Recruiting No phase listed Observational

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

NCT05600946
View directory record Official record
Conditions
Cognitive Disorder, Metabolic Disease, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
2 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 23, 2026, 7:36 PM EDT