Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:56 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Total Knee Arthroplasty Biomechanics

NCT03671954
Conditions
Total Knee Arthroplasty (TKA)
Interventions
Home Strengthening Exercises, Standard Physical Therapy, Preoperative Assessments
Behavioral · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
4
States / cities
Gainesville, Florida
Conditions
Adipocytic Neoplasm, Liposarcoma, Atypical Fibroxanthoma, Angiomatoid Fibrous Histiocytoma, Fibrosarcoma NOS, Myxofibrosarcoma, Angiosarcoma, Osteosarcoma, Extraskeletal, Dedifferentiated Liposarcoma, Myxoid Liposarcoma, Pleomorphic Liposarcoma, Myxoid Pleomorphic Liposarcoma, Low Grade Fibromyxoid Sarcoma, Sclerosing Epithelioid Fibrosarcoma, Malignant Tenosynovial Giant Cell Tumor of Soft Tissue, Epithelioid Hemangioendothelioma, Glomus Tumor, Inflammatory Leiomyosarcoma, Leiomyosarcoma, Ossifying Fibromyxoid Tumor, Malignant, Myoepithelioma, Synovial Sarcoma, Epithelioid Sarcoma, Perineurioma, Malignant, Clear Cell Sarcoma, Extraskeletal Myxoid Chondrosarcoma, Granular Cell Tumor, Malignant, Melanotic Malignant Nerve Sheath Tumor, Malignant Peripheral Nerve Sheath Tumor, Perivascular Epithelioid Tumor, Malignant, Intimal Sarcoma, Myoepithelial Carcinoma, Undifferentiated Sarcoma, Pleomorphic Sarcoma, Undifferentiated, Round Cell Sarcoma, Undifferentiated, NTRK-Rearranged Spindle Cell Neoplasm, Phosphaturic Mesenchymal Tumor, Malignant, Round Cell Sarcoma, Well Differentiated Liposarcoma, Giant Cell Tumor of Soft Parts NOS, Low Grade Myofibroblastic Sarcoma, Dermatofibrosarcoma Protuberans, Fibrosarcomatous
Interventions
Surgical resection, Proton beam radiation therapy, Pazopanib, Ifosfamide, Doxorubicin, Selinexor
Procedure · Radiation · Drug
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
Up to 30 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2037
U.S. locations
7
States / cities
Atlanta, Georgia • Chicago, Illinois • Baton Rouge, Louisiana + 4 more
Conditions
Neurofibromatosis Type 1, Von Recklinghausen Disease, NF1
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years and older
Enrollment
645 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Muscle Hypotrophy
Interventions
Carnipure AAS, Creatine Monohydrate
Dietary Supplement
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Quadriceps Motor Unit Adaptation to Simulated Knee Injury

NCT06999057
Conditions
Muscle Inhibition, Knee Injury Simulation
Interventions
Joint Effusion via 60 mL Sterile Saline, Intra-articular Lidocaine, Sham injection
Device · Drug · Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Myasthenia Gravis
Interventions
Telehealth
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
New Haven, Connecticut • Washington D.C., District of Columbia • Chicago, Illinois + 2 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Sex Hormones and Aging

NCT07848438
Conditions
Menopause, Menopausal Hormone Therapy, Aging
Interventions
HRT: High-Resistance Strength Training, Control: High-Resistance Strength Training
Other
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 70 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Myasthenia Gravis, MG, gMG, Generalized Myasthenia Gravis, Generalized Myasthenia Gravis (gMG), AChR-Ab Seropositive Generalized Myasthenia Gravis
Interventions
Efgartigimod IV, Empasiprubart IV, Placebo IV, Efgartigimod PH20 SC PFS
Biological · Other
Lead sponsor
argenx
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
15
States / cities
Carlsbad, California • Miami, Florida • Tampa, Florida + 11 more
Completed Phase 2Phase 3 Interventional

Tailored Treatments of Fibromyalgia

NCT00000422
Conditions
Fibromyalgia
Interventions
Cognitive-behavioral psychotherapy and physical exercise
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Neuromuscular Training on EEG Adaptations in Young Athletes

NCT03913975
Conditions
Brain Concussion
Interventions
Neuromuscular training
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 19 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Results available

Time Course Adaptations Using Deuterated Creatine (D3Cr) Method

NCT03573583
Conditions
Sarcopenia
Interventions
Resistance Training, Successful Aging
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
70 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Gainesville, Florida
Conditions
Physical Fitness
Interventions
Balanced Progressive Intensity Training (BPIT) 5-Line Method
Behavioral
Lead sponsor
MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
369 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
3
States / cities
Columbus, Ohio • Powell, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

THRIVE Well Cancer FDTN/Exercise_Creatine Supplementation

NCT06395506
Conditions
Breast Cancer, Breast Cancer Female, Muscle Weakness
Interventions
Creatine
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Galveston, Texas
Conditions
Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Obesity, Muscle Loss, Older Adults
Interventions
Calcium-HMB Plus Vitamin D3, Matching placebo
Dietary Supplement · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
65 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Nashville, Tennessee
Recruiting Not applicable Interventional Accepts healthy volunteers

Gait Adaptation and Biofeedback for Cerebral Palsy

NCT05899153
Conditions
Cerebral Palsy
Interventions
Biomotum Spark: Robotic ankle resistance, Audiovisual Biofeedback, Multilevel Orthopedic Surgery
Device · Procedure
Lead sponsor
University of Washington
Other
Eligibility
7 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Activity, Motor
Interventions
10% Velocity-Loss Threshold Resistance Training, 30% Velocity-Loss Threshold Resistance Training
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
50 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Coral Gables, Florida
Completed Not applicable Interventional

Activity for Diabetic Polyneuropathy

NCT02341261
Conditions
Diabetic Neuropathy
Interventions
Standard Care Counseling, Supervised Exercise and Counseling
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
30 Years to 75 Years
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
2
States / cities
Kansas City, Kansas • Salt Lake City, Utah
Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Myasthenia Gravis, MG, gMG, Generalized Myasthenia Gravis, Generalized Myasthenia Gravis (gMG)
Interventions
Efgartigimod IV, Empasiprubart IV
Biological
Lead sponsor
argenx
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
14
States / cities
Carlsbad, California • Miami, Florida • Tampa, Florida + 11 more
Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Myasthenia Gravis (MG), MG - Myasthenia Gravis, gMG
Interventions
Empasiprubart IV, Placebo IV, Efgartigimod PH20 SC PFS
Biological · Other · Combination Product
Lead sponsor
argenx
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
6
States / cities
Carlsbad, California • Miami, Florida • Las Vegas, Nevada + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training

NCT01083901
Conditions
Sarcopenia, Osteoporosis, Aging
Interventions
Resistance training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older · Male only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Recruiting Not applicable Interventional Accepts healthy volunteers

Squat Jump Performance and Chiropractic Ankle Manipulation

NCT07641621
Conditions
Athletic Performance, Neuromuscular Adaptations, Lower Limb, Chiropractic Manipulation
Interventions
Manual Therapy Procedure: Chiropractic Ankle Manipulation
Other
Lead sponsor
Northeast College of Health Sciences
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Seneca Falls, New York
Conditions
Weakness, Muscle
Interventions
Placebo, Indus810
Dietary Supplement
Lead sponsor
The Center for Applied Health Sciences, LLC
Industry
Eligibility
18 Years to 45 Years · Male only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stow, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Immune Function and Muscle Adaptations to Resistance Exercise in Older Adults

NCT02261961
Conditions
Sarcopenia, Aging, Immune Function
Interventions
TDAP, Acute Resistance Exercise, Resistance Exercise Training, Post-training Follow-up, Nutritional Supplement (Muscle Armor), Placebo (Kool-Aid)
Biological · Other · Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 80 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
North Little Rock, Arkansas
Conditions
Breast Cancer, Chemotherapy Effect, Muscle Weakness, Muscle Loss, Exercise
Interventions
Creatine
Dietary Supplement
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Antonio, Texas