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ClinicalTrials.gov public records Last synced Sep 13, 2026, 9:33 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Neurosurgery Clear all
Completed Not applicable Interventional Results available

INVEST Feasibility - Minimally Invasive Endoscopic Surgery With Apollo in Patients With Brain Hemorrhage

NCT02654015
View directory record Official record
Conditions
Intracranial Hemorrhage
Interventions
Apollo MIES, Medical Management
Device · Other
Lead sponsor
J. Mocco
Other
Eligibility
22 Years to 84 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Louisville, Kentucky • Buffalo, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Completed No phase listed Observational

Correlation of PaCO2 to the Inspired and Expired Oxygen Gradient

NCT01513213
View directory record Official record
Conditions
Neurosurgery
Interventions
Not listed
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2017 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and Vomiting

NCT01474915
View directory record Official record
Conditions
Postoperative Nausea and Vomiting (PONV), Nausea
Interventions
Aprepitant, Ondansetron, Promethazine, Dexamethasone
Drug
Lead sponsor
Sergio Bergese
Other
Eligibility
18 Years to 85 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 2, 2013 · Synced Sep 13, 2026, 9:33 PM EDT
Terminated Phase 2 Interventional Results available

Seizure Prophylaxis in Patients With Glioma or Brain Metastasis

NCT03436433
View directory record Official record
Conditions
Glioma, Glioma of Brain, Brain Tumor
Interventions
Lacosamide, Levetiracetam
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 99 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Actigraphic Measurement of a Neurosurgical Procedure

NCT00945230
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm, Pain, Rehabilitation, Mood Lability
Interventions
Re-section of a large left anterior cranial fossa meningioma
Procedure
Lead sponsor
Child Psychopharmacology Institute
Other
Eligibility
21 Years to 75 Years · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 23, 2009 · Synced Sep 13, 2026, 9:33 PM EDT
Recruiting Phase 1Phase 2 Interventional

Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery

NCT03510208
View directory record Official record
Conditions
Malignant Brain Neoplasm, Malignant Glioma
Interventions
Near-Infrared Fluorescence Imaging, Panitumumab, Panitumumab-IRDye800, POINPOINT-IR9000
Procedure · Biological · Drug + 1 more
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Phase 2 Interventional

A Study Comparing Two Treatments for Infants With Hydrocephalus

NCT00652470
View directory record Official record
Conditions
Hydrocephalus
Interventions
Endoscopic Third Ventriculostomy, CSF Shunt Insertion
Procedure
Lead sponsor
The Hospital for Sick Children
Other
Eligibility
1 Day to 24 Months
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 9, 2018 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Evaluating the Impact That Personnel Traffic Through the Operating Room Has on Surgical Site Infections

NCT01783769
View directory record Official record
Conditions
Neurological Diseases
Interventions
"Low O.R. Traffic"
Behavioral
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
1,944 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Sep 13, 2026, 9:33 PM EDT
Not yet recruiting No phase listed Observational

Real Time Craniotomy Planning Using Mixed Reality

NCT07468370
View directory record Official record
Conditions
Neurosurgery, Surgical Planning, Brain Tumor Adult, Craniotomy Tumor Removal Surgery
Interventions
Mixed Reality Glasses/Viewer, Survey using a questionnaire.
Device · Other
Lead sponsor
Brainlab AG
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

SOLITAIRE™ FR With the Intention For Thrombectomy (SWIFT) Study

NCT01054560
View directory record Official record
Conditions
Ischemic Stroke
Interventions
SOLITAIRE™ Device, MERCI® Device
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Portland, Oregon • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Sep 13, 2026, 9:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Hyperglycemia in Neurosurgery

NCT05236751
View directory record Official record
Conditions
Hyperglycemia, Postoperative Infection
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional Results available

INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage

NCT02661672
View directory record Official record
Conditions
Intracranial Hemorrhage
Interventions
Apollo Device, Artemis Device
Device
Lead sponsor
J. Mocco
Other
Eligibility
22 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
7
States / cities
Washington D.C., District of Columbia • Louisville, Kentucky • Buffalo, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 13, 2026, 9:33 PM EDT
Terminated Not applicable Interventional

Safety Study to Evaluate Intracranial Pressure During High Frequency Chest Wall Oscillation

NCT00279097
View directory record Official record
Conditions
Intracranial Pressure
Interventions
High Frequency Chest Wall Oscillation
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2006 · Synced Sep 13, 2026, 9:33 PM EDT
Enrolling by invitation Not applicable Interventional

An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy

NCT00859794
View directory record Official record
Conditions
Epilepsy
Interventions
fMRI, Neuropsychological Testing, Additional electrode implantation, Electrical brain stimulation
Other
Lead sponsor
Northwell Health
Other
Eligibility
5 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2029
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Sep 13, 2026, 9:33 PM EDT
Terminated Not applicable Interventional Results available

Comparison of EVD Catheter Diameter on Occlusion and Replacement

NCT03248739
View directory record Official record
Conditions
Occlusion
Interventions
Clear Bactiseal 'large' catheter (EVD), Orange Bactiseal 'small' catheter (EVD)
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multidisciplinary Teamwork Perceptions When Mobilizing Ventilated Neurosurgery Patients

NCT05583487
View directory record Official record
Conditions
Multidisciplinary Communication
Interventions
Nurse-led progressive mobility protocol, Standard of Care
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Recruiting Phase 1Phase 2 Interventional

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

NCT04085887
View directory record Official record
Conditions
Brain Tumor
Interventions
Panitumumab-IRDye800, Pinpoint-IR9000 endoscopic/handheld device, Explorer Air camera, PDE-NEO-II
Drug · Device
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 25 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Dexmedetomidine on Intraoperative Somatosensory and Motor Evoked Potential Monitoring During Neurosurgery in Pediatric Patients

NCT01512147
View directory record Official record
Conditions
Tethered Spinal Cord, Brain Tumor, Cranio Cervical Compression
Interventions
Isoflurane, Propofol, Dexmedetomidine
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Phase 1 Interventional

VY-AADC02 for Parkinson's Disease With Motor Fluctuations (RESTORE-1)

NCT03562494
View directory record Official record
Conditions
Parkinson's Disease
Interventions
VY-AADC02, Sham (Placebo) Surgery
Biological · Other
Lead sponsor
Neurocrine Biosciences
Industry
Eligibility
40 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
11
States / cities
Irvine, California • Sacramento, California • San Francisco, California + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 13, 2026, 9:33 PM EDT
Withdrawn Not applicable Interventional

Decision Aids in Cerebral Aneurysm Treatment

NCT02503553
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Option grid for cerebral aneurysm treatment, Control
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Phase 2 Interventional Results available

TXA in Spinal Fusion

NCT04272606
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
Drug · Diagnostic Test
Lead sponsor
Catherine R. Olinger
Other
Eligibility
18 Years to 90 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Sep 13, 2026, 9:33 PM EDT
Completed Not applicable Interventional

Distribution of Medication Disposal Packets - Acute Opioid Prescribing

NCT05169281
View directory record Official record
Conditions
Orthopedic Surgery, Neurosurgery, Surgery, Opioid Use, Opioid Misuse
Interventions
Medication Disposal Packet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Sep 13, 2026, 9:33 PM EDT
Recruiting Not applicable Interventional

Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions

NCT04047264
View directory record Official record
Conditions
Glioma, Glioblastoma, Metastatic Malignant Neoplasm in the Brain
Interventions
Microdialysis, Magnetic Resonance Imaging, Computed Tomography
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 13, 2026, 9:33 PM EDT
Not listed Phase 4 Interventional

ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study

NCT01881711
View directory record Official record
Conditions
Suspected CSF Shunt Obstruction
Interventions
ShuntCheck-Micro-Pumper (SCMP), Imaging
Device
Lead sponsor
NeuroDx Development
Industry
Eligibility
35 Months to 29 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
11
States / cities
Wilmington, Delaware • Washington D.C., District of Columbia • Chicago, Illinois + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2015 · Synced Sep 13, 2026, 9:33 PM EDT