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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Non-invasive Brain Stimulation Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression

NCT05194098
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
TMS: single session intermittent theta burst stimulation (iTBS) to dorsomedial prefrontal target in individuals with major depressive disorder, via MagVenture MagPro R30 device / Cool-DB80 A/P coil, SHAM (inactive) TMS stimulation
Device
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2024 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Non-invasive VNS in Stroke Recovery

NCT06761404
View directory record Official record
Conditions
Stroke
Interventions
taVNS
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

NCT07523685
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder PTSD, PTSD - Post Traumatic Stress Disorder, Post Traumatic Stress Disorder, Post Traumatic Stress Disorders, Post-traumatic Stress Disorder (PTSD), Post-Traumatic Stress Disorder, PTSD
Interventions
non-invasive vagus nerve stimulation
Device
Lead sponsor
Acacia Clinics
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sunnyvale, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

Non-invasive Neurostimulation of the Vagus Nerve for the Treatment of Cluster Headache

NCT01792817
View directory record Official record
Conditions
Cluster Headache
Interventions
GammaCore, Sham GammaCore device
Device
Lead sponsor
ElectroCore INC
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
20
States / cities
Santa Monica, California • Stanford, California • Englewood, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Improving Measurement and Treatment of Post-stroke Neglect

NCT03317860
View directory record Official record
Conditions
Stroke
Interventions
Sham tDCS, Active tDCS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural Mechanisms of Interpersonal Expectations on Negative Affect

NCT06980090
View directory record Official record
Conditions
Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
Interventions
Session A: Positive Placebo + Active tTIS, Session B: Positive Placebo + Sham tTIS, Session C: Negative Placebo + Active tTIS, Session D: Negative Placebo + Sham tTIS, Session E: On-Placebo + Sham tTIS, Session F: Off-Placebo + Sham tTIS
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years to 55 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol

NCT04770025
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
High-density transcranial alternating current stimulation, Sham stimulation, Motivational interviewing
Device · Behavioral
Lead sponsor
The Mind Research Network
Other
Eligibility
21 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1

NCT03896425
View directory record Official record
Conditions
Transcranial Direct Current Stimulation, Healthy
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation for PTSD and Sleep

NCT03170440
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcutaneous nerve stimulation location 1
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

Non-Invasive Brain Stimulation and Substance Use

NCT03122587
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Transcranial Alternating Current Stimulation at 10 Hz, Transcranial Alternating Current Stimulation at 40 Hz, Active sham transcranial alternating current stimulation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 55 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Jul 23, 2026, 5:00 PM EDT
Terminated Not applicable Interventional Results available

SHARPEN - Parkinson's Disease Dementia

NCT05987540
View directory record Official record
Conditions
Parkinson Disease Dementia
Interventions
Non-invasive brainstem stimulation
Device
Lead sponsor
Scion NeuroStim
Industry
Eligibility
50 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Boca Raton, Florida • Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Spinal Cord Stimulation for Parkinson's Disease Rehabilitation

NCT06804642
View directory record Official record
Conditions
Parkinson Disease
Interventions
Spinal cord transcutaneous stimulation (scTS)
Device
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2035
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Results available

Home-based tDCS in Major Depressive Disorder

NCT04799405
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
tDCS
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
50 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation

NCT01958437
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer's Disease
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 88 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Decatur, Georgia • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Individualized Neuro-Modulation Paired With Cerebellar Therapy

NCT07642856
View directory record Official record
Conditions
Cerebellar Ataxia, Cerebellar Diseases, Cerebellar Stroke, Cerebellar Tumor
Interventions
Therapy
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Combined EEG and Non-invasive Brain Stimulation to Examine and Improve Reward Functioning in Opioid Use Disorder

NCT04432493
View directory record Official record
Conditions
Opioid-use Disorder
Interventions
Active repetitive transcranial magnetic stimulation (rTMS), Sham repetitive transcranial magnetic stimulation (rTMS)
Device
Lead sponsor
Rutgers University
Other
Eligibility
18 Years to 55 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments

NCT05479006
View directory record Official record
Conditions
Stroke
Interventions
Transcranial direct current stimulation (high- definition)
Device
Lead sponsor
Carle Foundation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

NCT06891638
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Schedule of tDCS administration
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury

NCT06848140
View directory record Official record
Conditions
Traumatic Brain Injury, Word Finding Difficulty, Cognitive Symptom, Cognitive Change, Acquired Brain Injury
Interventions
Active Transcranial direct current stimulation, Sham Transcranial direct current stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

NCT07469384
View directory record Official record
Conditions
SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Interventions
transcranial direct current stimulation, Sham stimulation
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Active, not recruiting Not applicable Interventional

Individualized Non-invasive Brain Stimulation for the Treatment of Major Depressive Disorder

NCT06874374
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Transcranial Alternating Current Stimulation
Interventions
Closed-loop tACS, Sham Comparator
Device
Lead sponsor
Pulvinar Neuro, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

NCT07044596
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Concussion Syndrome
Interventions
Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Investigation of Neural Plasticity

NCT06453980
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
sham tDCS, active tDCS
Device
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 23, 2026, 5:00 PM EDT
Completed Not applicable Interventional

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

NCT04777149
View directory record Official record
Conditions
Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
Interventions
transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS), sham-stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Jul 23, 2026, 5:00 PM EDT