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ClinicalTrials.gov public records Last synced Oct 14, 2026, 10:02 PM EDT

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Showing 457–480 of 17,926 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Nutritional and Metabolic Disease Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Determine the Utility of Novel Technologies and Biomarkers to Measure Human Response to Rosiglitazone Maleate

NCT00551564
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
rosiglitazone maleate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 14, 2026, 10:02 PM EDT
Recruiting Phase 4 Interventional

SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial

NCT06674109
View directory record Official record
Conditions
Gout and Hyperuricemia
Interventions
Empagliflozin 10 mg, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating the Relationship Between Physical Activity, Diet, Weight, and the Neighborhood Environment for Adolescents

NCT00608036
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Dr. James Sallis
Other
Eligibility
12 Years to 16 Years
Enrollment
954 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
2
States / cities
San Diego, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2020 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Phase 2 Interventional

Alternative Dosing and Regimen of Replagal to Treat Fabry Disease

NCT00075244
View directory record Official record
Conditions
Fabry Disease
Interventions
Replagal
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 14, 2026, 10:02 PM EDT
Completed No phase listed Observational

Bone Disease in Chronic Pancreatitis: A Complex Phenomenon

NCT02108509
View directory record Official record
Conditions
Chronic Pancreatitis, Osteopenia, Osteoporosis
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 75 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Oct 14, 2026, 10:02 PM EDT
Recruiting Phase 3 Interventional

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

NCT07743463
View directory record Official record
Conditions
Obesity, Overweight, Chronic Weight Management
Interventions
ASC30 tablets A1, Placebo
Drug
Lead sponsor
Ascletis Pharma (China) Co., Limited
Industry
Eligibility
18 Years and older
Enrollment
3,003 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
69
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 65 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Phase 1 Interventional

A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes

NCT00398619
View directory record Official record
Conditions
Insulin Resistance, Obesity
Interventions
INCB13739
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
2
States / cities
Beverly Hills, California • Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2012 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Phase 3 Interventional Results available

Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity

NCT04788511
View directory record Official record
Conditions
Obesity
Interventions
Semaglutide, Placebo (semaglutide)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
529 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
50
States / cities
Fairhope, Alabama • Beverly Hills, California • Los Angeles, California + 41 more
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 14, 2026, 10:02 PM EDT
Completed No phase listed Observational Results available

Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network

NCT01586871
View directory record Official record
Conditions
Mucopolysaccharidoses
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
3 Years to 18 Years
Enrollment
1,147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Orange, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Diabetes Prevention Program Pilot Study

NCT05358444
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood, Obesity, Childhood, Lifestyle, Healthy
Interventions
National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Grocery Prescription Program for Medicaid Adults With Hypertension or Type 2 Diabetes

NCT06033664
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Hypertension
Interventions
Fresh Funds
Behavioral
Lead sponsor
Alison Gustafson
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional

Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)

NCT01464398
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological, Stress, Psychological
Interventions
Stress reduction, Stress reduction with Health education
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 14, 2015 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neuroimaging Study of Factors Related to Exercise

NCT02010463
View directory record Official record
Conditions
Obesity
Interventions
Exercise
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2020
U.S. locations
2
States / cities
Kansas City, Kansas • Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 14, 2026, 10:02 PM EDT
Terminated Phase 4 Interventional Results available

LOSS- Louisiana Obese Subjects Study

NCT00115063
View directory record Official record
Conditions
Obesity
Interventions
group sessions, sibutramine, orlistat, diethylpropion, Low Calorie Diet, Health One, Intensive Medical Combination Therapy for Obesity, Control Condition
Behavioral · Drug · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 60 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Oct 14, 2026, 10:02 PM EDT
Recruiting Phase 2 Interventional

A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

NCT07395687
View directory record Official record
Conditions
Overweight, Obesity
Interventions
UBT251, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 65 Years
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Cypress, California • Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Phase 3 Interventional

A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight

NCT06388187
View directory record Official record
Conditions
Obesity
Interventions
Cagrilintide, Semaglutide, Placebo
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Costa Mesa, California • Plantation, Florida • Indianapolis, Indiana + 4 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Phase 4 Interventional Results available

Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health

NCT00679939
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Rosiglitazone, Metformin
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
55 Years to 80 Years · Female only
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
21
States / cities
Tucson, Arizona • Huntington Park, California • Los Angeles, California + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional Results available

Postpartum Weight Loss for Women at Elevated Cardiovascular Risk

NCT04914819
View directory record Official record
Conditions
Weight Loss, Postpartum Weight Retention, Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy, Preeclampsia, Recruitment
Interventions
Online Behavioral Weight Loss Program, Virtual weigh-in
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 14, 2026, 10:02 PM EDT
Completed No phase listed Observational

Prospective Evaluation of Adjusted Body Weight Dosing of Acyclovir in Obesity

NCT02879630
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Withdrawn No phase listed Observational

Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

NCT05102071
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Interventions
empagliflozin, metformin, sulfonylurea
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ridgefield, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Oct 14, 2026, 10:02 PM EDT
Recruiting Phase 1Phase 2 Interventional

64Cu-GRIP B in Patients With Advanced Malignancies

NCT05888532
View directory record Official record
Conditions
Prostate Cancer, Renal Cancer, Urethral Cancer, Advanced Solid Tumor, Metastatic Castration-resistant Prostate Cancer, Solid Tumor, Adult
Interventions
Copper-64 labeled Granzyme B (64Cu-GRIP B), Positron Emission Tomography (PET)
Drug · Procedure
Lead sponsor
Rahul Aggarwal
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Oct 14, 2026, 10:02 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Exercise-Induced Gut Permeability in Normal-weight Obesity

NCT05889767
View directory record Official record
Conditions
Normal-weight Obesity, Obesity
Interventions
Exercise tests (VO2 max test and 45-minute exercise session at 65% VO2 max)
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 14, 2026, 10:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of the SMART Device for Overweight and Obese Adults

NCT02119299
View directory record Official record
Conditions
Overweight and Obesity
Interventions
SMART device
Device
Lead sponsor
Scientific Intake Limited Co.
Industry
Eligibility
18 Years to 49 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
4
States / cities
San Diego, California • Waterbury, Connecticut • Coral Gables, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Oct 14, 2026, 10:02 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants

NCT07629999
View directory record Official record
Conditions
Healthy Volunteers
Interventions
BMS-986533, Famotidine, Placebo, Dabigatran Etexilate, Rosuvastatin
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
18 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 14, 2026, 10:02 PM EDT