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ClinicalTrials.gov public records Last synced Nov 13, 2026, 7:50 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 641 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Obese Adults Clear all

Conditions: Obesity, Type 2 Diabetes
Interventions: Aspartame, Sucrose, Stevia; Dietary Supplement
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 45 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Obesity
Interventions: Daily self-weighing (DSW); Device
Lead sponsor: University of Georgia; Other
Eligibility: 18 Years to 75 Years
Enrollment: 111 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Type 2 Diabetes
Interventions: vitamin D3, cholecalciferol, Inactive comparator; Dietary Supplement
Lead sponsor: Augusta University; Other
Eligibility: 19 Years to 60 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Obesity, Overweight, Weight Loss, Health Behavior, Lifestyle Intervention
Interventions: Core Behavioral Weight Loss Intervention, Limit Red Zone Foods, Limit Eating Window, Increase Protein, Increase Fiber Intake; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 208 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Overweight, Obesity
Interventions: Semaglutide Nasal Spray, Placebo, Semaglutide Injection; Drug
Lead sponsor: Shanghai World Leader Pharmaceutical Co., Ltd.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Secaucus, New Jersey

Conditions: Obesity
Interventions: Maridebart Cafraglutide, Placebo; Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 3,853 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 74
States / cities: Anniston, Alabama • Daphne, Alabama • Mobile, Alabama + 59 more

Conditions: Weight Management, Treatment Of Obesity
Interventions: CE-326,597 100 mg QD, CE-326,597 50 mg QD, CE-326,597 25 mg QD, Placebo, CE-326,597 5mg QD; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 30
States / cities: Phoenix, Arizona • Fresno, California • National City, California + 23 more

Conditions: Overweight, Obesity
Interventions: Not listed
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 23 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Obesity, PreDiabetes, Aging
Interventions: DPP Intensive: 30-minute calls, DPP Support: 15-minute calls; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 60 Years and older
Enrollment: 314 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity, Overweight
Interventions: No TV viewing reduction, TV viewing reduction; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 21 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Obesity, Insulin Resistance
Interventions: Weight loss with very low fat plant-based diet and regular exercise; Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 55 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Obesity
Interventions: Intensive behavioral therapy for obesity; Behavioral
Lead sponsor: University of Southern Mississippi; Other
Eligibility: 25 Years to 50 Years
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Hattiesburg, Mississippi

Conditions: Obesity
Interventions: Social/mobile weight loss promotion intervention.; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 35 Years
Enrollment: 404 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Non-Alcoholic Steatohepatitis
Interventions: SHP626, Placebo; Drug
Lead sponsor: Mirum Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Knoxville, Tennessee

Conditions: Obese Individuals, Central Adiposity
Interventions: Beetroot Juice - Active + Exercise, Beetroot juice placebo + Exercise, Beetroot Juice - Active + No exercise, Beetroot juice placebo+ No exercise; Dietary Supplement
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 40 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Obesity
Interventions: Behavioral Weight Loss (BWL), BWL + Autonomous Motivation, BWL + Extrinsic Motivation; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 25 Years
Enrollment: 382 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Obesity, Physical Activity, Weight Loss, Weight Change, Body
Interventions: Hatha Yoga Intervention, Vinyasa Yoga Intervention; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity
Interventions: Resistance Exercise; Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 20 Years to 45 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Hyperglycemia
Interventions: High-Intensity Functional Training, Aerobic and Resistance Training; Other
Lead sponsor: Kansas State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Manhattan, Kansas

Conditions: Obesity, Insufficient Sleep
Interventions: sleep extension intervention, contact control intervention; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 75 Years
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Hyper-LDL-cholesterolemia, Metabolic Syndrome
Interventions: strawberries, Control powder; Dietary Supplement · Other
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years to 65 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 3
States / cities: Las Vegas, Nevada • Oklahoma City, Oklahoma • Stillwater, Oklahoma

Conditions: Sedentary Lifestyle
Interventions: i-STAND, Healthy Living control; Behavioral · Other
Lead sponsor: Kaiser Permanente; Other
Eligibility: 60 Years to 89 Years
Enrollment: 283 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Healthy Participants, Obesity
Interventions: AZD1043, Placebo; Drug · Other
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Glendale, California • Brooklyn, Maryland

Conditions: Overweight, Obesity
Interventions: Deaf Weight Wise 2.0; Behavioral
Lead sponsor: University of Rochester; Other
Eligibility: 21 Years to 70 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Rochester, New York

Search by objective public record fields.

Effects of Stevia on Satiety and Eating Attitudes in Healthy, Overweight and Obese Adults

Daily Self-weighing and Holiday-associated Weight Gain in Adults

The Effect of Vitamin D Supplementation on Glucose Metabolism in Non-Diabetic African American Adults

Reset: Enhancing Weight Loss in a Digital Intervention

A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

A Trial In Diabetic Patients To Assess Effect Of CE-326,597 On Glucose Control And Body Weight

Relationship of Adverse Childhood Experiences to Overweight and Obesity

Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes

The Relationship of TV Viewing to Energy Balance in Adults

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

Telenutrition Center: Examining the Implementation of Behavioral Therapy for Obesity

SMART: A Social and Mobile Weight Control Program for Young Adults

Safety and Tolerability Study of SHP626 in Overweight and Obese Adults

Post-exercise Blood Pressure With Inorganic Nitrate

Low Intensity Weight Loss for Young Adults

Integration of Yoga for the Treatment of Obesity in Adults

Resistance Exercise and Muscle Protein Synthesis in Obese Adults

CrossFit Exercise to Improve Glucose Control for Overweight and Obese Adults

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

The Effects of Strawberries on Blood Cholesterol.

Healthy Aging Resources to Thrive (HART)

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

Deaf Weight Wise 2.0: A Healthy Lifestyle Intervention With Deaf Adults Who Are Overweight or Obese