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Showing 1–24 of 468 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obesity, Adolescent Clear all
Completed No phase listed Observational Accepts healthy volunteers

Discordance of Obesity in Adolescent Sibilngs

NCT02376439
View directory record Official record
Conditions
Obesity
Interventions
Kool-aid
Other
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
13 Years to 17 Years
Enrollment
176 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 12, 2026, 3:43 PM EDT
Not yet recruiting No phase listed Observational

Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults

NCT07388537
View directory record Official record
Conditions
Obesity, Diabetes, Metabolic Disorders
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
8 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2055
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Housecalls: Redesigning Pediatric Primary Care Adolescent Obesity Treatment

NCT07246603
View directory record Official record
Conditions
Class I Obesity, Pediatric Obesity
Interventions
Virtual Housecalls
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 15 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Sleep Timing and Insulin Resistance in Adolescents With Obesity

NCT02585830
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
15 Years to 19 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 18, 2020 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Results available

Tolerability, Acceptance, and Utility of Intermittent CGM Use in Youth With Prediabetes

NCT05505565
View directory record Official record
Conditions
PreDiabetes, Obesity, Insulin Resistance
Interventions
Abbott Freestyle Libre 2, Standard physical activity and nutritional counseling for prediabetes management
Device · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
11 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases

NCT00001723
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension, Metabolic Disease, Obesity, Sleep Apnea Syndrome
Interventions
Orlistat, Placebo
Drug
Lead sponsor
Jack Yanovski
NIH
Eligibility
12 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2012 · Synced Sep 12, 2026, 3:43 PM EDT
Enrolling by invitation Not applicable Interventional

ESG in Obese Adolescents

NCT06914765
View directory record Official record
Conditions
Obese Adolescents, Obesity, Morbid, Obesity/Therapy
Interventions
Endoscopic Sleeve Gastroplasty (ESG) Procedure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
12 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of High Intensity Interval Training in the Treatment of Adolescent Obesity

NCT03361644
View directory record Official record
Conditions
Pediatric Obesity, Adolescent Obesity, Weight Loss
Interventions
High-Intensity Interval Training, Moderate-Intensity Continuous Training
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
12 Years to 16 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Healthy Eating, Activity and Reduction of Teen Stress

NCT04038684
View directory record Official record
Conditions
Overweight and Obesity, Overweight Adolescents, Emotional Stress, Stress, Psychological, Eating Behavior
Interventions
Mindfulness-Based Weight Control (MBWC), Standard Behavioral Weight Control (SBWC)
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
13 Years to 18 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional

A Coordinated Parent/Child Dyad Weight Loss Intervention: Dyad Plus (Feasibility)

NCT03811743
View directory record Official record
Conditions
Weight Loss, Pediatric Obesity
Interventions
Brenner FIT, By Design, Coordination
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
13 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls

NCT01169103
View directory record Official record
Conditions
Obesity
Interventions
recombinant human growth hormone (rhGH), Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 21 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Sep 12, 2026, 3:43 PM EDT
Withdrawn Phase 2 Interventional

ADI-PEG20, Obesity and Prediabetes

NCT05829239
View directory record Official record
Conditions
Obesity, PreDiabetes
Interventions
ADI-PEG20, Placebo
Biological · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 22 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Early Phase 1 Interventional Results available

Pharmacokinetics and Pharmacodynamics of Topiramate for Weight Loss in Youth: PHARMATOP

NCT04986631
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Topiramate Tablets
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 18 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Beneficial Effects of a Protein-rich Breakfast on Appetite Control & Cognition in Overweight and Obese Adolescents

NCT01192100
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Breakfast Skipping, Normal Protein Breakfast Meals, Protein-rich Breakfast Meals
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
15 Years to 20 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional

Families Improving Together (FIT) for Weight Loss

NCT01796067
View directory record Official record
Conditions
Overweight, Obese
Interventions
Motivational and Family Weight Loss, Basic Health Education, Online Intervention, Online Control
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
11 Years to 16 Years
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Health Literacy and Obesogenic Behaviors

NCT04252677
View directory record Official record
Conditions
Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy, Exercise, Health Literacy
Interventions
Obesity Prevention, Health Literacy
Behavioral
Lead sponsor
City University of New York, School of Public Health
Other
Eligibility
13 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Phase 2 Interventional Results available

Topiramate in Adolescents With Severe Obesity

NCT01859013
View directory record Official record
Conditions
Obesity, Morbid, Obesity, Weight Loss
Interventions
Topiramate, Placebo
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Learning to BREATHE: A Randomized Controlled Trial to Lower Diabetes Risk in Adolescent Girls

NCT02218138
View directory record Official record
Conditions
Type 2 Diabetes, Depression, Obesity
Interventions
Learning 2 BREATHE, Colorado Blues
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Sep 12, 2026, 3:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Addressing Anxiety and Stress for Healthier Eating in Teens

NCT05038033
View directory record Official record
Conditions
Obesity, Overweight, Anxiety, Mental Disorders, Body Weight, Eating Behavior, Feeding and Eating Disorders
Interventions
Interpersonal Psychotherapy (IPT), Cognitive Behavioral Theory (CBT)
Behavioral
Lead sponsor
The Metis Foundation
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Fort Collins, Colorado • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 7, 2021 · Synced Sep 12, 2026, 3:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents

NCT06959901
View directory record Official record
Conditions
Obesity and Diabetes Mellitus, Type 2, Diabetes Prevention
Interventions
PATHS-UP Mobile Phone Application
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Recruiting Phase 2 Interventional

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

NCT05414409
View directory record Official record
Conditions
Type 1 Diabetes, Obesity
Interventions
Metformin
Drug
Lead sponsor
Heba M. Ismail
Other
Eligibility
11 Years to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 12, 2026, 3:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Get Fruved: Obesity Prevention for Older Adolescents

NCT02941497
View directory record Official record
Conditions
Obesity
Interventions
Social marketing and health promotion campaign
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
Up to 24 Years
Enrollment
5,800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
7
States / cities
Gainesville, Florida • Manhattan, Kansas • Orono, Maine + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Sep 12, 2026, 3:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Generation Fit and Exerlearning With In the Groove"

NCT00424918
View directory record Official record
Conditions
Obesity
Interventions
Physical Activity, reduced sedentary behavior
Behavioral
Lead sponsor
MaineHealth
Other
Eligibility
10 Years to 14 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Portland, Maine
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Sep 12, 2026, 3:43 PM EDT
Completed No phase listed Observational Results available

Hepatic Mitochondrial Function in Youth

NCT03587727
View directory record Official record
Conditions
Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 20 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 12, 2026, 3:43 PM EDT