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ClinicalTrials.gov public records Last synced Oct 5, 2026, 2:05 PM EDT

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Showing 25–48 of 254 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obesity, Prediabetes Clear all
Completed Phase 4 Interventional Results available

Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults

NCT05786521
View directory record Official record
Conditions
Aging, Diabetes Mellitus, Type 2, PreDiabetes, Overweight and Obesity
Interventions
Semaglutide Injectable Product, Lifestyle Counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
65 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional

Cocoa and Metabolic Health in Prediabetes

NCT02203240
View directory record Official record
Conditions
Prediabetes
Interventions
Cocoa, Placebo
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
40 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Cardiometabolic Risk and Promoting Functional Health in Older Adults With Obesity and Prediabetes

NCT03500640
View directory record Official record
Conditions
Obesity, PreDiabetes, Aging
Interventions
DPP Intensive: 30-minute calls, DPP Support: 15-minute calls
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

Clinical Effectiveness of Body Fat Distribution Imaging in Real-World Practice: The BODY-REAL Study

NCT04763772
View directory record Official record
Conditions
Overweight and Obesity, PreDiabetes, Type 2 Diabetes, Cardiovascular Risk Factor
Interventions
Body Fat Distribution Imaging Report, Basic Weight Information, Patient Provided, Physician Provided
Diagnostic Test · Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
35 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Phase 4 Interventional

Once Weekly GLP-1 in Persons With Spinal Cord Injury

NCT03292315
View directory record Official record
Conditions
Spinal Cord Injuries, Insulin Resistance, Pre Diabetes, Obesity
Interventions
Semaglutide 1MG Injection [Ozempic], No Intervention
Drug · Other
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 69 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 14, 2023 · Synced Oct 5, 2026, 2:05 PM EDT
Active, not recruiting Not applicable Interventional

Full Plate Living Nutrition Education Program

NCT07271940
View directory record Official record
Conditions
Diabetes Mellitus, Pre Diabetes, Obesity
Interventions
Full Plate Living Nutrition Education Program
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
22 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Active, not recruiting Not applicable Interventional

The PIVOT Trial: Project on EHR-Integrated Lifestyle Interventions for Adults Aged Fifty and Older

NCT05654142
View directory record Official record
Conditions
CARDIOMETABOLIC CONDITIONS, Obesity, Pre-diabetes, Metabolic Syndrome, Type2diabetes, Hypertension, Dyslipidemias
Interventions
Base intervention, Augmented Intervention
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 74 Years
Enrollment
1,029 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
3
States / cities
Chicago, Illinois • St Louis, Missouri • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

TRE With Physical Activity for Weight Management

NCT04978376
View directory record Official record
Conditions
Pre Diabetes, Overweight and Obesity
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
50 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

SGLT2 Inhibition in Older Obese Adults With Pre-diabetes

NCT04401904
View directory record Official record
Conditions
Aging
Interventions
Dapagliflozin 10 mg, Nutritional counseling
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 5, 2024 · Synced Oct 5, 2026, 2:05 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Social Determinants and a Diabetes Prevention Program Tailored for African Americans

NCT05301413
View directory record Official record
Conditions
PreDiabetes, Overweight and Obesity
Interventions
Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, Diabetes Prevention Program
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Clinical Utility of SUDOSCAN in the Pediatric Population

NCT02216201
View directory record Official record
Conditions
Childhood Obesity, Prediabetes, Diabetes
Interventions
Not listed
Lead sponsor
Impeto Medical
Industry
Eligibility
8 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 11, 2014 · Synced Oct 5, 2026, 2:05 PM EDT
Terminated Not applicable Interventional

Examining the Effects of Diet on Health in Prediabetes With an Online Program

NCT02188823
View directory record Official record
Conditions
Prediabetes
Interventions
Low carbohydrate diet
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 5, 2026, 2:05 PM EDT
Not listed Not applicable Interventional

Effect of Gelesis200 on Body Weight in Overweight and Obese Subjects w/o Type 2 Diabetes

NCT03058029
View directory record Official record
Conditions
Overweight, Diabetes, PreDiabetes, Obesity
Interventions
Gelesis200, Placebo
Device
Lead sponsor
Gelesis, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
12
States / cities
Birmingham, Alabama • Bradenton, Florida • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 5, 2026, 2:05 PM EDT
Active, not recruiting Not applicable Interventional

Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women

NCT06360536
View directory record Official record
Conditions
Overweight or Obesity, Prediabetes or Diabetes, Prehypertension (Elevated Blood Pressure) or Hypertension, Resistance Training
Interventions
Resistance Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
30 Years to 64 Years · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Results available

Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults

NCT02706093
View directory record Official record
Conditions
Glucose Intolerance
Interventions
High Intensity Interval Training (HIIT), Moderate-intensity continuous training (MICT)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional

CardioMetabolic Program Meets eHealth: Redesign and Evaluation for Optimal Reach and Impact

NCT02246400
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Pre-diabetes, Type 2 Diabetes, Cardiovascular Disease
Interventions
eCMP
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional

The Snack Study: The Feasibility of Changing Night-time Food Choices to Improve Glucose Tolerance in Pregnancy

NCT02634593
View directory record Official record
Conditions
Glucose Intolerance, Obesity
Interventions
Low glycemic load snacks
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
16 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Quantitative 18F-AV-133 PET Imaging in Subjects With Diabetes and Healthy Controls

NCT01710371
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
18F-AV-133, 10% Arginine Hydrochloride-R-Gene 10
Drug
Lead sponsor
Avid Radiopharmaceuticals
Industry
Eligibility
30 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 5, 2026, 2:05 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

NCT06007404
View directory record Official record
Conditions
Type 2 Diabetes, Insulin Resistance, Obesity, Metabolic Disease, PreDiabetes
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 18 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional

DPP Feasibility Study of Breastfeeding - eMOMS 2.0

NCT06372860
View directory record Official record
Conditions
Overweight or Obesity, Pregnancy
Interventions
Diabetes Prevention Program, Breastfeeding, Usual Care
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Phase 1Phase 2 Interventional Results available

SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot

NCT04907214
View directory record Official record
Conditions
Obesity, Pre-diabetes
Interventions
Empagliflozin 25 MG
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 29, 2023 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Presessions for the National Diabetes Prevention Program

NCT04022499
View directory record Official record
Conditions
Prediabetic State, Obesity, Gestational Diabetes
Interventions
Presessions, National Diabetes Prevention Program
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 5, 2026, 2:05 PM EDT
Active, not recruiting Phase 4 Interventional

The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans

NCT03938389
View directory record Official record
Conditions
PreDiabetes, Impaired Glucose Tolerance, Obesity, Blood Pressure
Interventions
Sacubitril-Valsartan Tab 97-103 MG, Valsartan 160mg, Placebo Oral Tablet
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 5, 2026, 2:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Extended Use of the EPITOMEE CAPSULE (ELECT)

NCT04994769
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Epitomee Capsule
Device
Lead sponsor
Epitomee medical
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Birmingham, Alabama • Winston-Salem, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 5, 2026, 2:05 PM EDT