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Showing 1–24 of 223 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obesity, Severe Clear all
Completed Not applicable Interventional

Treatment of Low Metabolic Rate Following Bariatric Surgery

NCT01596907
View directory record Official record
Conditions
Morbid Obesity
Interventions
Ephedrine sulfate with caffeine, cellulose
Drug
Lead sponsor
Oregon Weight Loss Surgery, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Beaverton, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Sep 23, 2026, 8:16 PM EDT
Not listed Not applicable Interventional

Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients

NCT01460667
View directory record Official record
Conditions
Morbid Obesity
Interventions
IV acetaminophen, IV normal saline
Drug
Lead sponsor
McLaren Regional Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 26, 2011 · Synced Sep 23, 2026, 8:16 PM EDT
Not yet recruiting Not applicable Interventional

Continuous Glucose Monitoring in Metabolic Surgery

NCT07095972
View directory record Official record
Conditions
Obesity (Disorder)
Interventions
Abbot Freestyle Libre CGM
Device
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
20 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Recruiting Not applicable Interventional

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

NCT05918575
View directory record Official record
Conditions
Obesity, Morbid, Extubation Failure
Interventions
Noninvasive ventilation alternating with high flow nasal cannula, High flow nasal cannula
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
4
States / cities
Chicago, Illinois • Winfield, Illinois • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Recruiting No phase listed Observational

Metabolic Responses to Bariatric Surgery

NCT02024542
View directory record Official record
Conditions
Morbid Obesity
Interventions
Surgery
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 55 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2035
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated Not applicable Interventional

Esophageal Balloon Guided Weaning of the Morbidly Obese Patient

NCT02323009
View directory record Official record
Conditions
Morbid Obesity
Interventions
Esophageal Balloon, Cstat
Device · Other
Lead sponsor
East Carolina University
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2014 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Not applicable Interventional

Effect of Number of Meals on Metabolism After Weight Loss Surgery

NCT02929212
View directory record Official record
Conditions
Morbid Obesity
Interventions
Solid Meal, Liquid Meal, Acetaminophen, Single, 600 kcal meal, Multiple, 200 kcal meals
Other · Drug
Lead sponsor
Columbia University
Other
Eligibility
21 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 31, 2017 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Results available

Multicenter Prospective Randomized Controlled Trial of Plicated Laparoscopic Adjustable Gastric Banding

NCT01564732
View directory record Official record
Conditions
Morbid Obesity
Interventions
Standard-LAGB, Plicated-LAGB
Device
Lead sponsor
Dana Portenier, MD
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2016 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Not applicable Interventional Results available

Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity

NCT05343000
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Home-based pulmonary rehabilitation (PR) system
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated No phase listed Observational

Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip

NCT01759550
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated No phase listed Observational

Study Evaluating Metabolic Syndrome in Subjects Undergoing Gastric Bypass Bariatric Syndrome

NCT00283374
View directory record Official record
Conditions
Morbid Obesity, Metabolic Disease
Interventions
Laparoscopic Roux-en-Y Gastric Bypass
Procedure
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
10
States / cities
Irvine, California • Orange, California • Atlanta, Georgia + 6 more
Source: ClinicalTrials.gov public record
Updated May 17, 2006 · Synced Sep 23, 2026, 8:16 PM EDT
Completed No phase listed Observational

Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton

NCT02778490
View directory record Official record
Conditions
Calcium Metabolism Disorders, Morbid Obesity
Interventions
Not listed
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
25 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2022 · Synced Sep 23, 2026, 8:16 PM EDT
Recruiting Phase 4 Interventional

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

NCT06857942
View directory record Official record
Conditions
Psoriasis, Overweight or Obesity
Interventions
Tirzepatide
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
39
States / cities
Phoenix, Arizona • Fountain Valley, California • Fremont, California + 35 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Single Incision Laparoscopic Gastric Banding Versus Conventional Five Port Laparoscopic Gastric Banding

NCT01039077
View directory record Official record
Conditions
Morbid Obesity
Interventions
Laparoscopic gastric banding
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 60 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Sep 23, 2026, 8:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery

NCT04644445
View directory record Official record
Conditions
Bariatric Surgery Candidate, Postoperative Nausea and Vomiting, Morbid Obesity
Interventions
Bariatric Full Liquid Diet
Dietary Supplement
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 8, 2020 · Synced Sep 23, 2026, 8:16 PM EDT
Not yet recruiting Not applicable Interventional

Inhaled Nitric Oxide in Severe Obesity

NCT06675435
View directory record Official record
Conditions
Obesity, Respiratory Insufficiency, Hypoxemic Respiratory Failure, Nitric Oxide
Interventions
Nitric oxide
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Phase 4 Interventional Results available

Exenatide for the Treatment of Weight Gain Associated With Olanzapine in Obese Adults

NCT00845507
View directory record Official record
Conditions
Weight Gain
Interventions
Exenatide, Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Sep 23, 2026, 8:16 PM EDT
Withdrawn Not applicable Interventional

EasyBand GOAL Trial

NCT00534339
View directory record Official record
Conditions
Morbid Obesity
Interventions
Easyband (Telemetrically adjustable gastric banding device)
Device
Lead sponsor
Allergan Medical
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
USA, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2014 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Not applicable Interventional

Determinants of Fat Malabsorption After Roux-en-Y Gastric Bypass

NCT01252511
View directory record Official record
Conditions
Severe Obesity
Interventions
RYGB for surgical treatment of severe obesity
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2019 · Synced Sep 23, 2026, 8:16 PM EDT
Withdrawn No phase listed Observational

Omega-3 Fatty Acid Status in Morbid Obesity Before and After Surgical Treatment

NCT00558532
View directory record Official record
Conditions
Morbid Obesity, Cardiovascular Disease, Fatty Acid Levels
Interventions
Bariatric Surgery
Procedure
Lead sponsor
University of Cincinnati
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2016 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated No phase listed Observational

Studies of Biological Changes Related to Weight Loss After Gastric Bypass Surgery

NCT00120562
View directory record Official record
Conditions
Obesity, Morbid Obesity, Weight Loss
Interventions
Gastric Bypass Surgery
Procedure
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Sep 23, 2026, 8:16 PM EDT
Completed Not applicable Interventional

Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates

NCT00887393
View directory record Official record
Conditions
Morbid Obesity, Non-alcoholic Fatty Liver Disease
Interventions
low carbohydrate diet, low-fat diet
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Sep 23, 2026, 8:16 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Time-restricted Eating Among Pregnant Females With Severe Obesity

NCT06477120
View directory record Official record
Conditions
Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
Interventions
Time Restricted Eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Sep 23, 2026, 8:16 PM EDT
Terminated Phase 2 Interventional

Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus

NCT01083108
View directory record Official record
Conditions
Obesity, Bariatric Surgery, Morbid Obesity, Diabetes Mellitus Type 2, Diet Therapy
Interventions
Roux-en-Y Gastric Bypass, Caloric Restriction
Other
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
3
States / cities
Baltimore, Maryland • Bethesda, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 23, 2026, 8:16 PM EDT