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ClinicalTrials.gov public records Last synced Oct 6, 2026, 4:15 AM EDT

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Showing 49–72 of 345 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obesity in Adolescence Clear all
Completed Phase 2Phase 3 Interventional Results available

Treating PCOS With Semaglutide vs Active Lifestyle Intervention

NCT03919929
View directory record Official record
Conditions
PCOS, Adolescent Obesity, NAFLD
Interventions
Semaglutide 3mg and 7mg [Rybelsus], Weight loss diet
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 21 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 6, 2026, 4:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Examining the Relationship Between Tobacco Exposure, Abdominal Obesity, and Metabolic Syndrome in Adolescents (The STRONG Kids Study)

NCT00808158
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
9 Years to 10 Years
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 30, 2012 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Not applicable Interventional

Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents

NCT01901978
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Caloric restrictive diet
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 32 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2020 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Nutritional Choices in Adolescents

NCT03693144
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Full LIITA3H App, Partial LIITA3H App, LIITA3H Location only
Other
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 6, 2026, 4:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls

NCT06723028
View directory record Official record
Conditions
Obesity and Type 2 Diabetes, Diet Modification
Interventions
Regulation of craving training
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
15 Years to 18 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Laramie, Wyoming
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

NCT00139477
View directory record Official record
Conditions
Obesity
Interventions
Metformin, Dietary modification with caloric restriction, Establishment of exercise protocol
Drug · Behavioral
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
7 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inhibitory Control and Pediatric Weight Management

NCT04747548
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Kurbo Only, Kurbo + PolyRules!
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
7 Years to 13 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes Adolescents for Healthier Lifestyles Study

NCT06878872
View directory record Official record
Conditions
Type 1 Diabetes, Eating Behavior, Adolescent Obesity
Interventions
T1DAL Program
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effect of Ketone Esters on Liver Fat Content and Metabolic Function

NCT07097506
View directory record Official record
Conditions
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Obesity, Overweight (BMI > 25)
Interventions
bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester), Placebo
Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed No phase listed Observational

Be-HealthY: Behavioral Risk Factors for Poor Vascular Health in Youth

NCT03934398
View directory record Official record
Conditions
Prehypertension, Hypertension, Overweight and Obesity, Elevated Blood Pressure, Endothelial Dysfunction, Vascular Stiffness, Sleep
Interventions
Cardiovascular Assessments, Actigraphy, Laboratory assessments, Emotional/Behavioral Assessments
Diagnostic Test
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 22 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents

NCT06007404
View directory record Official record
Conditions
Type 2 Diabetes, Insulin Resistance, Obesity, Metabolic Disease, PreDiabetes
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 18 Years
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Active, not recruiting Not applicable Interventional

Low GI Diet in Children and Adolescents With ALL

NCT03157323
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Pediatric, Obesity, Pediatric
Interventions
Low Glycemic Index Diet
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 21 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
5
States / cities
Hartford, Connecticut • Washington D.C., District of Columbia • Buffalo, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Summer Youth Employment Programs for Health Promotion

NCT07227220
View directory record Official record
Conditions
Obesity, Childhood, Behavior, Health, Healthy Lifestyle
Interventions
Summer Youth Employment Program
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
14 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Puberty and Weight on Sugar Metabolism in Children

NCT01718080
View directory record Official record
Conditions
Overweight, Leanness, Adolescent
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 17 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Phase 4 Interventional Results available

The Health Influences of Puberty (HIP) Study

NCT01775813
View directory record Official record
Conditions
Obesity, Insulin Resistance, Gonadal Dysfunction, Type 2 Diabetes
Interventions
Metformin, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
9 Years to 17 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Phase 3 Interventional

Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

NCT05819853
View directory record Official record
Conditions
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
Interventions
Semaglutide Injectable Product (Wegovy and/or Ozempic)
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
12 Years to 35 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Phase 2 Interventional Results available

Break It Up: A Study Evaluating Breaking Up Daily Sedentary Behavior in Youth

NCT03223649
View directory record Official record
Conditions
Healthy, Obesity, Overweight
Interventions
Walking Bouts, Sedentary
Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
7 Years to 11 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Latino Fathers Promoting Healthy Youth Behaviors

NCT03469752
View directory record Official record
Conditions
Diet Modification, Physical Activity, Parenting, Adolescent Obesity
Interventions
Parent education classes
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 14 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2021 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Phase 2 Interventional

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

NCT05414409
View directory record Official record
Conditions
Type 1 Diabetes, Obesity
Interventions
Metformin
Drug
Lead sponsor
Heba M. Ismail
Other
Eligibility
11 Years to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Phase 1Phase 2 Interventional

Project HERA (Health, Education, and Relationship-building for Adolescents- Moms and Tots)

NCT02200484
View directory record Official record
Conditions
Child Behavior Problems, Parenting Skills, Obesity Prevention
Interventions
Combined parent training and obesity prevention program, Wellness program (active contact control)
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
16 Years to 20 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2015 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Phase 3 Interventional

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

NCT07253285
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Cagrilintide, Semaglutide, Placebo cagrilintide, Placebo semaglutide
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
8 Years to 18 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
34
States / cities
Escondido, California • Hollywood, Florida • Jacksonville, Florida + 29 more
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Phase 2 Interventional Results available

Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome

NCT02629991
View directory record Official record
Conditions
Prader-Willi Syndrome, Hyperphagia
Interventions
Intranasal Oxytocin (IN-OXT), Matched Placebo
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
5 Years to 18 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 6, 2026, 4:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Advancing Biopsychosocial Care Training Initiative

NCT07049861
View directory record Official record
Conditions
Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Obesity
Interventions
Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
5 Years and older
Enrollment
6,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 6, 2026, 4:15 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Single Dose Study to Determine the Safety, Tolerability, and Pharmacokinetic Properties of Lorcaserin Hydrochloride (BELVIQ) in Obese Adolescents From 12 to 17 Years of Age

NCT02022956
View directory record Official record
Conditions
Pharmacokinetics in Obese Adolescents
Interventions
Lorcaserin
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
12 Years to 17 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 6, 2026, 4:15 AM EDT