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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:27 PM EDT

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Showing 73–96 of 366 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive - Compulsive Disorder Clear all
Completed Phase 3 Interventional Results available

Intravenous Immunoglobulin for PANDAS

NCT01281969
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Children, Anxiety Disorder, Autoimmune Disease, PANDAS
Interventions
Gamunex Intravenous Immunoglobulin, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
4 Years to 13 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional

ERP Plus Improv Group Therapy for OCD (IMPROVE Study)

NCT06265233
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Group Improv sessions, Group Exposure and Response Prevention (ERP) Therapy
Other · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Terminated Phase 2Phase 3 Interventional

Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder

NCT00299611
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Sertraline, Levetiracetam, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 11, 2013 · Synced Oct 25, 2026, 12:27 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional

Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors

NCT05796752
View directory record Official record
Conditions
Skin-Picking, Trichotillomania (Hair-Pulling Disorder)
Interventions
Memantine, ComB Behavioral Therapy
Drug · Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional

Examining Behavior Therapy for Trichotillomania in Children and Adolescents

NCT00917098
View directory record Official record
Conditions
Trichotillomania
Interventions
Behavior Therapy, Supportive Counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
10 Years to 17 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 1, 2017 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional Results available

D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD

NCT01172873
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
D-cycloserine, Exposure and Response Prevention (EX/RP)
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional

A Study of Bitopertin (RO4917838) in Combination With Selective Serotonin Reuptake Inhibitors (SSRIs) in Participants With Obsessive-Compulsive Disorder (OCD)

NCT01674361
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Bitopertin, Placebo, SSRI
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 65 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
27
States / cities
Oceanside, California • Stanford, California • New Haven, Connecticut + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2017 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional

A Trial of Parent-coached Exposure Therapy for Children With Anxiety Disorders and OCD

NCT05777161
View directory record Official record
Conditions
Anxiety Disorders, Obsessive-Compulsive Disorder
Interventions
Parent Coached Exposure Therapy - Individualized, Cognitive Behavior Therapy, Parent Coached Exposure Therapy - Group (removed from study)
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Phase 1 Interventional

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

NCT07347405
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Psilocybin 10 mg, Psilocybin 20 mg, Psilocybin 30 mg
Drug
Lead sponsor
Francisco A Moreno
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Terminated Not applicable Interventional

The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens

NCT02998502
View directory record Official record
Conditions
Anxiety, Panic Disorder
Interventions
Freespira Breathing System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
9 Years to 17 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional Results available

Milk Thistle in Trichotillomania in Children and Adults

NCT02473913
View directory record Official record
Conditions
Trichotillomania, Hair Pulling Disorder
Interventions
Milk Thistle, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
10 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 25, 2026, 12:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Parenting Styles and Child Temperament Associated With Child Anxiety Disorders

NCT00517244
View directory record Official record
Conditions
Anxiety Disorders, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
Rhode Island Hospital
Other
Eligibility
8 Years to 12 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 11, 2016 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional

Theta Burst Stimulation Plus Habit Override Training for Compulsive Behaviors

NCT04580043
View directory record Official record
Conditions
Compulsive Behavior, Obsessive-Compulsive Disorder
Interventions
Habit Override Practice, Transcranial Magnetic Stimulation, Sham Training, Sham Transcranial Magnetic Stimulation
Behavioral · Device
Lead sponsor
Rebecca Price
Other
Eligibility
18 Years to 60 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Not applicable Interventional

OCD LIFU Target Engagement

NCT07558148
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 25, 2026, 12:27 PM EDT
Withdrawn No phase listed Observational

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obsessive-Compulsive Disorder

NCT04211402
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
No Intervention
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Not applicable Interventional

Contingency Management for Hoarding Disorder

NCT04894851
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Contingency Management
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 25, 2026, 12:27 PM EDT
Not listed Phase 2 Interventional

The Use of D-Cycloserine to Augment CBT for Pediatric OCD

NCT01687140
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
D-Cycloserine, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
7 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2012 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional Results available

N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder

NCT01172275
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
N-Acetylcysteine, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
8 Years to 17 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 25, 2026, 12:27 PM EDT
Withdrawn No phase listed Observational

Patient-specific, Effective, and Rational Functional Connectivity Targeting for DBS in OCD

NCT03244852
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 25, 2026, 12:27 PM EDT
Withdrawn No phase listed Observational

ON/OFF Stimulation and Impulsivity in Patients With Deep Brain Stimulators

NCT01506206
View directory record Official record
Conditions
Obsessive Compulsive Disorder, Major Depressive Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 2 Interventional

St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.

NCT00035438
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
St. John's Wort
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
2
States / cities
Oklahoma City, Oklahoma • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 4, 2006 · Synced Oct 25, 2026, 12:27 PM EDT
Completed Phase 4 Interventional

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome

NCT05657860
View directory record Official record
Conditions
Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking
Interventions
Guanfacine Extended Release, Placebo
Drug · Other
Lead sponsor
Maimonides Medical Center
Other
Eligibility
6 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 25, 2026, 12:27 PM EDT
Recruiting Not applicable Interventional

DBS for Obsessive-Compulsive Disorder

NCT02773082
View directory record Official record
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Reclaim™ DBS Therapy
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Queens, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 25, 2026, 12:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electrophysiological Recording for Patients Receiving Deep Brain Stimulation Electrode for Treatment-resistant Obsessive-compulsive Disorder

NCT01429558
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 25, 2026, 12:27 PM EDT