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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:36 PM EDT

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Showing 1–24 of 365 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obsessive-Compulsive Disorder (OCD) Clear all
Recruiting Not applicable Interventional

Acceptance and Commitment Therapy for Religious OCD

NCT06647589
View directory record Official record
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time

NCT06705179
View directory record Official record
Conditions
Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
Interventions
Behavioral task performance
Behavioral
Lead sponsor
California Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
1,100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Pasadena, California
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 27, 2026, 1:36 PM EDT
Withdrawn Not applicable Interventional

Individual Versus Group Exposure With Response Prevention (ERP) for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT03926546
View directory record Official record
Conditions
OCD
Interventions
ERP for Individuals
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 27, 2020 · Synced Oct 27, 2026, 1:36 PM EDT
Terminated Phase 2 Interventional

Naltrexone SR and Fluoxetine Combination Therapy in Subjects With Obsessive-Compulsive Disorder

NCT00758966
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Fluoxetine 60 mg, Naltrexone 32 mg and fluoxetine 60 mg, Naltrexone SR 32 mg
Drug
Lead sponsor
Orexigen Therapeutics, Inc
Industry
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
11
States / cities
National City, California • San Diego, California • Gainesville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Oct 27, 2026, 1:36 PM EDT
Terminated Phase 2 Interventional Results available

Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD

NCT02206776
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Intranasal Ketamine, Intranasal Midazolam
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Phase 4 Interventional Results available

Duloxetine for the Treatment of Obsessive Compulsive Disorder (OCD)

NCT00464698
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Duloxetine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 27, 2026, 1:36 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Neurocircuitry of Obsessive-Compulsive Disorder: Modulation by Transcranial Magnetic Stimulation

NCT02704117
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magentic Stimulation
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

NCT01919970
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder

NCT00045903
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and Ritual Prevention (Cognitive Behavioral Therapy), Stress Management Therapy (Cognitive Behavior Therapy)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2014 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Phase 2 Interventional Results available

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

NCT01695291
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Minocycline, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
8 Years to 20 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive Disorder

NCT00864123
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Cognitive-behavioral therapy, D-cycloserine, Placebo pill
Behavioral · Drug
Lead sponsor
University of South Florida
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2012 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Phase 2 Interventional Results available

Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)

NCT00728923
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
NPL-2003
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2012 · Synced Oct 27, 2026, 1:36 PM EDT
Withdrawn Not applicable Interventional

Using Virtual Reality Before Transcranial Magnetic Stimulation for the Treatment of OCD

NCT06442527
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Virtual Reality
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Electrophysiological Recording for Patients Receiving Deep Brain Stimulation Electrode for Treatment-resistant Obsessive-compulsive Disorder

NCT01429558
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Phase 3 Interventional Results available

Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder

NCT00674219
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
Interventions
Memantine
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 64 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 10, 2019 · Synced Oct 27, 2026, 1:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sensory Symptoms in Tourette Syndrome and Obsessive-Compulsive Disorder

NCT04335175
View directory record Official record
Conditions
Tourette Syndrome, Obsessive-Compulsive Disorder, Sensory Disorders
Interventions
None - observational study
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 27, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional

Anxiety Skills Study

NCT07774481
View directory record Official record
Conditions
Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders, Social Anxiety Disorder, Panic Disorder (With or Without Agoraphobia), Generalized Anxiety Disorder, Obsessive-Compulsive Disorder, Specific Phobia
Interventions
Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Motivational Interviewing to Enhance Behavioral Change in Older Adults With Hoarding Disorder

NCT05237466
View directory record Official record
Conditions
Hoarding Disorder
Interventions
RECLAIM: Reducing Clutter and Increasing Meaning, Sorting Practice
Behavioral
Lead sponsor
Mississippi State University
Other
Eligibility
60 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Terminated Not applicable Interventional Results available

Cognitive Behavioral Strategies and Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Open Label Study

NCT02528331
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Transcranial magnetic stimulation, Cognitive behavioral therapy
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Oct 27, 2026, 1:36 PM EDT
Active, not recruiting Not applicable Interventional

Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder

NCT03184454
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Medtronic Percept Deep Brain Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Charlestown, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 27, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Project EMPOWER-OCD

NCT07158801
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Project EMPOWER-OCD, Project CARE
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Not applicable Interventional

TMS + Exposure Therapy for Pediatric OCD

NCT05931913
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Transcranial Magnetic Stimulation: intermittent theta burst to dorsolateral prefrontal cortex, Exposure with Response Prevention, Transcranial Magnetic Stimulation: Sham, Transcranial Magnetic Stimulation: continuous theta burst to pre supplementary motor area
Device · Behavioral
Lead sponsor
Bradley Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Minneapolis, Minnesota • Riverside, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Computerized Intervention Targeting the Error-Related Negativity and Balance N1 in Anxious Children

NCT05503017
View directory record Official record
Conditions
Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Obsessive-Compulsive Disorder
Interventions
Psycho-social, computerized intervention targeting error sensitivity, Psycho-social, computerized intervention on healthy lifestyle choices
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
9 Years to 12 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 27, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional

Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms

NCT07103902
View directory record Official record
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Moderate-Intensity Exercise, Low-Intensity Exercise
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 27, 2026, 1:36 PM EDT