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ClinicalTrials.gov public records Last synced Oct 15, 2026, 11:12 PM EDT

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Showing 289–312 of 4,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Clear all
Completed Phase 2 Interventional Results available

A Safety and Efficacy Study of Tralokinumab in Adults With Asthma

NCT01402986
View directory record Official record
Conditions
Asthma
Interventions
Placebo Q2W, Tralokinumab 300 mg, Q2W, Placebo, Q2/4W, Tralokinumab 300 mg, Q2/4W
Other · Biological
Lead sponsor
MedImmune LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
689 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
11
States / cities
Rancho Mirage, California • Centennial, Colorado • New Haven, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 15, 2026, 11:12 PM EDT
Withdrawn Not applicable Interventional

Novel Therapies for Muco-Obstructive Lung Diseases: Testing the Transnasal Pulmonary Delivery Device in COPD/CB Subjects

NCT02341183
View directory record Official record
Conditions
COPD, Chronic Bronchitis
Interventions
tPAD, 7% hypertonic saline (510K approved as a device)
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 23, 2017 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 2 Interventional

Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)

NCT00391820
View directory record Official record
Conditions
Chronic Constipation
Interventions
TD-5108
Drug
Lead sponsor
Alfasigma S.p.A.
Industry
Eligibility
18 Years to 64 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 15, 2026, 11:12 PM EDT
Not listed Not applicable Interventional

Use of Semen TEX101 to Improve Sperm Retrieval Rates for Men With Non-obstructive Azoospermia

NCT02851966
View directory record Official record
Conditions
Non-obstructive Azoospermia
Interventions
mTESE
Procedure
Lead sponsor
Mount Sinai Hospital, Canada
Other
Eligibility
18 Years and older · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
San Francisco, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Oct 15, 2026, 11:12 PM EDT
Recruiting No phase listed Observational

The ROAM Research Study Therapy (LTOT) Version

NCT06810323
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 15, 2026, 11:12 PM EDT
Not listed No phase listed Observational

Sleep Apnea in Look AHEAD (Action for Health in Diabetes)

NCT00194259
View directory record Official record
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
45 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2014
U.S. locations
4
States / cities
New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2014 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional Results available

E-Visit for COPD and Smoking Cessation

NCT04155073
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive, Cigarette Smoking, Telemedicine
Interventions
smoking cessation, early COPD detection, electronic visit, Treatment As Usual
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional

The Effects of Exercise on Physiological and Psychological Parameters in an Asthmatic Population

NCT00825903
View directory record Official record
Conditions
Asthma, Bronchial
Interventions
Exercise
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated Jan 4, 2012 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional

Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD

NCT05259280
View directory record Official record
Conditions
COPD, Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Severe, Chronic Obstructive Pulmonary Disease Moderate
Interventions
Wellinks
Other
Lead sponsor
Convexity Scientific Inc
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
2
States / cities
New Haven, Connecticut • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 2, 2023 · Synced Oct 15, 2026, 11:12 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Using Community Health Workers to Support Rural Care Partners of Seriously Ill Older Veterans

NCT06963970
View directory record Official record
Conditions
Dementia, Cancer, Renal Disease, Obstructive Pulmonary Disease
Interventions
Remote Community Health Worker support
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 15, 2026, 11:12 PM EDT
Withdrawn Not applicable Interventional

Evaluation of a New Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea

NCT04063436
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
New nasal pillows mask with PAP therapy
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Dublin, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 2 Interventional

US Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study

NCT00515164
View directory record Official record
Conditions
Pulmonary Emphysema, Chronic Obstructive Pulmonary Disease
Interventions
Biologic Lung Volume Reduction (BLVR) - 20 mL Hydrogel
Drug
Lead sponsor
Aeris Therapeutics
Industry
Eligibility
40 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
8
States / cities
Phoenix, Arizona • Iowa City, Iowa • Topeka, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2011 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 2Phase 3 Interventional

Familiarization and Safety Study of PB127 Ultrasound Contrast Agent

NCT00594698
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
PB127 for injectable suspension
Drug
Lead sponsor
Point Biomedical
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
34
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Long Beach, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jul 3, 2008 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 2 Interventional Results available

Efficacy of Sofosbuvir With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant

NCT01559844
View directory record Official record
Conditions
Hepatitis C, Hepatocellular Carcinoma
Interventions
Sofosbuvir, Ribavirin
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
13
States / cities
Los Angeles, California • San Diego, California • San Francisco, California + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2016 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Techniques of Combination Therapy for Treatment of Obstructive Sleep Apnea (OSA)

NCT04029311
View directory record Official record
Conditions
Treatment for Obstructive Sleep Apnea
Interventions
Nuance Pro, autoPAP, TAP PAP
Device
Lead sponsor
Joseph Adame
Individual
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2021 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional Results available

Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy

NCT01863563
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
QuickClot
Device
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
2 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 26, 2019 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 3 Interventional Results available

Co-administration of Olodaterol Respimat® and Tiotropium Handihaler®

NCT01694771
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Tiotropium, Placebo matching Olodaterol, Olodaterol
Drug
Lead sponsor
Boehringer Ingelheim
Industry
Eligibility
40 Years and older
Enrollment
1,134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
90
States / cities
Florence, Alabama • Jasper, Alabama • Phoenix, Arizona + 79 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Oct 15, 2026, 11:12 PM EDT
Terminated Early Phase 1 Interventional

Effects of Melatonin in Untreated Obstructive Sleep Apnea

NCT03492736
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Melatonin, Placebo
Dietary Supplement · Other
Lead sponsor
Naomi Deacon
Other
Eligibility
30 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Oct 15, 2026, 11:12 PM EDT
Terminated Phase 2 Interventional Results available

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

NCT03345407
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Placebo ELLIPTA, Nemiralisib ELLIPTA 50 µg, Nemiralisib ELLIPTA 100 µg, Nemiralisib ELLIPTA 250 µg, Nemiralisib ELLIPTA 500 µg, Nemiralisib ELLIPTA 750 µg, Albuterol (Salbutamol) MDI or nebules, Standard of care therapy
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
40 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
21
States / cities
Mobile, Alabama • Colorado Springs, Colorado • Daytona Beach, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Oct 15, 2026, 11:12 PM EDT
Active, not recruiting Not applicable Interventional

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

NCT04801771
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Inspire Upper Airway Stimulation (UAS) System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
10 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Cincinnati, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers

NCT00565214
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
Group 1, Group 2
Dietary Supplement
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2017 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Phase 2 Interventional Results available

Safety and Tolerability of Repeat Dosing of GSK233705/GW642444 in COPD

NCT00749411
View directory record Official record
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Placebo, GSK233705/GW642444
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
40 Years to 80 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
12
States / cities
Mobile, Alabama • Wheat Ridge, Colorado • Biddeford, Maine + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Oct 15, 2026, 11:12 PM EDT
Completed Not applicable Interventional Results available

Metabolic Study of Sleep Apnea in Men and Women

NCT00706511
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
CPAP
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 15, 2026, 11:12 PM EDT
Withdrawn Not applicable Interventional

Whole Body Vibration for OSA

NCT03377621
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Whole Body Vibration
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 15, 2026, 11:12 PM EDT