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ClinicalTrials.gov public records Last synced Oct 27, 2026, 10:53 PM EDT

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Showing 481–504 of 825 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Apnea Clear all
Completed Phase 1Phase 2 Interventional Results available

DAW1033B2 in Obstructive Sleep Apnea

NCT03426631
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Placebo oral capsule, DAW1033B2 oral capsule
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Oct 27, 2026, 10:53 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea

NCT00936481
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 25, 2013 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Phase 2 Interventional Results available

AD109 Dose Finding in Mild to Moderate OSA

NCT04631107
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
AD109 dose1- A, AD109 dose2- B, Placebo- C
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
San Diego, California • Atlanta, Georgia • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 27, 2026, 10:53 PM EDT
Completed No phase listed Observational Results available

Patient Perception Questionnaire Validation

NCT02067000
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Obstructive Sleep Apnea
Behavioral
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Not applicable Interventional Results available

Race And CPAP Effectiveness

NCT01960465
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 70 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 27, 2026, 10:53 PM EDT
Terminated Phase 3 Interventional

Right to Left Cardiac Shunt Detection

NCT01773252
View directory record Official record
Conditions
Right to Left Shunt, Patent Foramen Ovale, Atrial Septal Defect
Interventions
Flow Detection System
Device
Lead sponsor
Cardiox Corporation
Industry
Eligibility
18 Years and older
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
8
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Not applicable Interventional Results available

The Evaluation of a New Nasal Mask for the Treatment of Obstructive Sleep Apnea

NCT04011826
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Device: Trial nasal mask (F&P)
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Oct 27, 2026, 10:53 PM EDT
Completed No phase listed Observational

New Data Analysis Methods for Actigraphy in Sleep Medicine

NCT00949858
View directory record Official record
Conditions
Obstructive Sleep Apnea, Restless Leg Syndrome, Insomnia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
635 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 27, 2026, 10:53 PM EDT
Recruiting Phase 1 Interventional

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

NCT03860233
View directory record Official record
Conditions
Sleep Apnea, Sleep Apnea, Obstructive
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Vivek Jain
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Phase 3 Interventional Results available

Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)

NCT05813275
View directory record Official record
Conditions
OSA
Interventions
AD109, Placebo
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years and older
Enrollment
646 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
65
States / cities
Tuscaloosa, Alabama • Mesa, Arizona • Phoenix, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 27, 2026, 10:53 PM EDT
Withdrawn Not applicable Interventional

Non-Inferiority Trial of Acute HFT Versus nCPAP

NCT01860560
View directory record Official record
Conditions
Mild-Moderate Obstructive Sleep Disordered Breathing
Interventions
High-Flow Therapy, Continuous Positive Airway Pressure
Device
Lead sponsor
Vapotherm, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Glen Burnie, Maryland
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 27, 2026, 10:53 PM EDT
Withdrawn Phase 2 Interventional

Post-Operative Steroids After Sleep Surgery

NCT06818981
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
8mg dexamethasone
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 27, 2026, 10:53 PM EDT
Terminated No phase listed Observational

Evaluation of Sleep Disordered Breathing Following Ambulatory Surgery

NCT01851798
View directory record Official record
Conditions
Sleep Disordered Breathing
Interventions
Home sleep test administered to all enrolled subjects
Other
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 85 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Oct 27, 2026, 10:53 PM EDT
Active, not recruiting Not applicable Interventional

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

NCT04801771
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Inspire Upper Airway Stimulation (UAS) System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
10 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Atlanta, Georgia • Boston, Massachusetts • Cincinnati, Ohio + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 27, 2026, 10:53 PM EDT
Withdrawn Not applicable Interventional

Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea

NCT00211614
View directory record Official record
Conditions
Obstructive Sleep Apnea, Gastroesophageal Reflux
Interventions
Lansoprazole
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Not applicable Interventional

US Development and Evaluation Study of a Patch-Based PSG System

NCT06881667
View directory record Official record
Conditions
Sleep Disorder (Disorder)
Interventions
Home PSG Assessment
Device
Lead sponsor
Onera BV
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Birmingham, Alabama • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Phase 2 Interventional Results available

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

NCT01187771
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Laparoscopic Gastric Banding, Continuous Positive Airway Pressure
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Oct 27, 2026, 10:53 PM EDT
Not listed Not applicable Interventional

eXciteOSA for Treatment of Mild Obstructive Sleep Apnea

NCT05183009
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
eXciteOSA
Device
Lead sponsor
Signifier Medical Technologies
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Birmingham, Alabama • Colorado Springs, Colorado • Lehigh Acres, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 27, 2026, 10:53 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Atrial Fibrosis in Obstructive Sleep Apnea Patients: A Pilot Study

NCT04814420
View directory record Official record
Conditions
Atrial Fibrillation, Obstructive Sleep Apnea
Interventions
Delayed enhancement magnetic resonance imaging (DE-MRI)
Device
Lead sponsor
Tulane University
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
3
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Nasal Expiratory Positive Airway Pressure for the Treatment of Pediatric Obstructive Sleep Apnea Syndrome

NCT01768065
View directory record Official record
Conditions
Organic Pediatric Obstructive Sleep Apnea
Interventions
Nasal Expiratory Positive Airway Pressure Device, placebo sham
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 16 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Phase 2 Interventional Results available

The Sleep, Liver Evaluation and Effective Pressure Study

NCT01482065
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease, Obstructive Sleep Apnea
Interventions
CPAP (ResMed S9 autoset CPAP)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2017 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Not applicable Interventional Results available

Right Ventricular Hemodynamics Using Cardiac MRI in Patients COPD and OSA

NCT02244957
View directory record Official record
Conditions
Obstructive Sleep Apnea, Chronic Obstructive Pulmonary Disease, Overlap Syndrome
Interventions
Bi-level positive airway pressure (BPAP), Nocturnal oxygen
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 27, 2026, 10:53 PM EDT
Withdrawn Not applicable Interventional

Effects of PAP Treatment of OSA in Patients With Heart Failure

NCT01136122
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP Treatment
Device
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 27, 2026, 10:53 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea

NCT03471871
View directory record Official record
Conditions
Obstructive Sleep Apnea, Healthy Subjects
Interventions
Placebo, Lemborexant 10 mg, Lemborexant 25 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
11
States / cities
Glendale, Arizona • Phoenix, Arizona • San Diego, California + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2020 · Synced Oct 27, 2026, 10:53 PM EDT