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ClinicalTrials.gov public records Last synced Sep 27, 2026, 1:38 AM EDT

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Showing 1–24 of 757 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Obstructive Sleep Apnea/Hypopnea Syndrome Clear all
Withdrawn Phase 1Phase 2 Interventional

Dex as Analgesic Adjuvant in OSA Patients

NCT03613558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 27, 2026, 1:38 AM EDT
Recruiting Phase 4 Interventional

Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea

NCT02630121
View directory record Official record
Conditions
Sleep Apnea, Chronic Nasal Congestion
Interventions
Oxymetazoline Hydrochloride, Placebo
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 27, 2026, 1:38 AM EDT
Withdrawn Phase 4 Interventional

Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients

NCT04205136
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Spironolactone, Placebo
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 18, 2022 · Synced Sep 27, 2026, 1:38 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

Continuation Protocol for Obstructive Sleep Apnea (OSA)

NCT06566820
View directory record Official record
Conditions
OSA
Interventions
Aroxybutynin and Atomoxetine
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years and older
Enrollment
1,280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
93
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Chandler, Arizona + 80 more
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Articulated Oral Airway as an Aid to Mask Ventilation

NCT03144089
View directory record Official record
Conditions
Mask Ventilation, Airway Obstruction Upper, Airway Management
Interventions
Articulated Oral Airway, Guedel oral airway (active comparator)
Device
Lead sponsor
Ron Abrons
Other
Eligibility
18 Years to 99 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Results available

Clinical Study for the BONGO Device in the Treatment of Obstructive Sleep Apnea (OSA)

NCT02878590
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
BONGO DEVICE
Device
Lead sponsor
InnoMed Healthscience Inc.
Industry
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment

NCT04744038
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Positive Airway Pressure (PAP) Therapy
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Sep 27, 2026, 1:38 AM EDT
Completed No phase listed Observational

Point-of-care-Ultrasound for Sleep Apnea

NCT04443582
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Rakesh Sondekoppam Vijayashankar
Other
Eligibility
18 Years to 85 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2022 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Phase 2 Interventional Results available

Trial of AD036 in Obstructive Sleep Apnea

NCT03845023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
AD036 Dose 1, AD036 Dose 2, AD036 Dose 3, Placebo
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 70 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
12
States / cities
Glendale, Arizona • Little Rock, Arkansas • Redwood City, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2023 · Synced Sep 27, 2026, 1:38 AM EDT
Not listed No phase listed Observational

Sleep Apnea in Look AHEAD (Action for Health in Diabetes)

NCT00194259
View directory record Official record
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
45 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2014
U.S. locations
4
States / cities
New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 6, 2014 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation of a Novel Device for Screening Patients With Symptoms of Obstructive Sleep Apnea

NCT04121923
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Sep 27, 2026, 1:38 AM EDT
Completed No phase listed Observational

Trans Nasal Insufflation for the Treatment of Snoring

NCT00832026
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Trans Nasal Insufflation (TNI) [nasal canula]
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 27, 2026, 1:38 AM EDT
Withdrawn No phase listed Observational

Post Discharge Circadian Rhythms Post Adenotonsillectomy

NCT03217708
View directory record Official record
Conditions
Circadian Dysrhythmia
Interventions
Jawbone UP4
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
5 Years to 10 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional

Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

NCT03736382
View directory record Official record
Conditions
Obstructive Sleep Apnea, Spinal Cord Injuries
Interventions
Mild intermittent hypoxia, Sham protocol, Continuous positive airway pressure (CPAP)
Other
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 60 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
2
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Changes in Pediatric OSA

NCT05368077
View directory record Official record
Conditions
Pediatric Obstructive Sleep Apnea
Interventions
Adenotonsillectomy
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
7 Years to 12 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 27, 2026, 1:38 AM EDT
Not listed No phase listed Observational

In-Hospital Portable Sleep Monitoring for the Evaluation of Obstructive Sleep Apnea (OSA)

NCT01424592
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Testing with a portable sleep apnea monitor .
Device
Lead sponsor
Cook County Health
Government
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Sep 27, 2026, 1:38 AM EDT
Recruiting Not applicable Interventional

The Recovery in Stroke Using PAP Study

NCT04130503
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
PAP, HLE
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Sep 27, 2026, 1:38 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea

NCT03109418
View directory record Official record
Conditions
Sleep Apnea, Obstructive Sleep Apnea, Postoperative Complications
Interventions
Ketamine, Control
Drug · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 100 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Results available

Comparative Effectiveness Research to Enhance Outcomes in African-Americans With Obstructive Sleep Apnea

NCT01997723
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Portable monitoring, Polysomnography, Home portable monitoring, Laboratory portable monitoring
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Pharmacological Activation of HMN for OSA

NCT03640052
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Placebo oral capsule, LTM1201L, LTM1201LN, LTM1201LB, LTM1201LD
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2020 · Synced Sep 27, 2026, 1:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device

NCT05570747
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Usability
Other
Lead sponsor
Bleep, LLC
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
3
States / cities
Asheville, North Carolina • Huntersville, North Carolina • Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Phase 2 Interventional Results available

Combination Drug-Therapy for Patients With Untreated Obstructive Sleep Apnea

NCT04639193
View directory record Official record
Conditions
OSA, Obstructive Sleep Apnea
Interventions
Acetazolamide, Eszopiclone, Placebo, Venlafaxine
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Sep 27, 2026, 1:38 AM EDT
Recruiting Phase 1Phase 2 Interventional

DRonabinol Treatment of OSA

NCT06477952
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Dronabinol
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 27, 2026, 1:38 AM EDT
Completed Not applicable Interventional Results available

Upper Airway Physical Therapy for the Treatment of Obstructive Sleep Apnea

NCT02109731
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Negative airway pressure delivery
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Sep 27, 2026, 1:38 AM EDT