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ClinicalTrials.gov public records Last synced Oct 13, 2026, 10:44 PM EDT

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Showing 241–264 of 761 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea/Hypopnea Syndrome Clear all
Recruiting Not applicable Interventional

PMOS in OSA Pilot Study

NCT07871149
View directory record Official record
Conditions
PCOS, PCOS (Polycystic Ovary Syndrome), OSA, OSA - Obstructive Sleep Apnea
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Recruiting Phase 2 Interventional

Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.

NCT06587256
View directory record Official record
Conditions
Mild Obstructive Sleep Apnea, Snoring
Interventions
Mouth Tape
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Metabolic Study of Women With Polycystic Ovary Syndrome and Sleep Apnea

NCT00696111
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Interventions
Depot Lupron followed by estrogen plus placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Phase 3 Interventional

Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)

NCT05811247
View directory record Official record
Conditions
OSA
Interventions
AD109, Placebo
Drug
Lead sponsor
Apnimed
Industry
Eligibility
18 Years and older
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
64
States / cities
Birmingham, Alabama • Chandler, Arizona • Little Rock, Arkansas + 59 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional

Increasing Adherence to Oral Appliance Therapy for Obstructive Sleep Apnea

NCT05038215
View directory record Official record
Conditions
Obstructive Sleep Apnea, Adherence, Patient
Interventions
adherence promotion techniques, Routine Care
Behavioral · Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 13, 2026, 10:44 PM EDT
Terminated Phase 2 Interventional Results available

Sleep Apnea Treatment After Stroke (SATS)

NCT00282815
View directory record Official record
Conditions
Obstructive Sleep Apnea, Stroke
Interventions
continuous positive airway pressure or CPAP, sham CPAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2013 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Predictors of the Metabolic Effect of Sleep Loss

NCT00965783
View directory record Official record
Conditions
Apnea, Obstructive Sleep Apnea (OSA), Obesity
Interventions
Restriction, Extension
Other
Lead sponsor
University of Chicago
Other
Eligibility
25 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2013 · Synced Oct 13, 2026, 10:44 PM EDT
Terminated Not applicable Interventional

Pediatric Obesity Management Study

NCT05622981
View directory record Official record
Conditions
Obesity, Childhood, Behavior, Eating
Interventions
Age-specific educational materials and monitoring
Behavioral
Lead sponsor
Corewell Health East
Other
Eligibility
2 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Phase 2Phase 3 Interventional

Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention

NCT00662623
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
i-PAP, Usual Care (Standard Care)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 13, 2026, 10:44 PM EDT
Recruiting No phase listed Observational

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

NCT07113288
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Inspire® UAS System
Device
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
5
States / cities
Colorado Springs, Colorado • Bradenton, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)

NCT02522442
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Auto BiLevel
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 13, 2026, 10:44 PM EDT
Withdrawn Phase 2 Interventional

Post-Operative Steroids After Sleep Surgery

NCT06818981
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
8mg dexamethasone
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Completed No phase listed Observational

The Prevalence of Sleep Disordered Breathing in Hospitalized Patients With Acutely Decompensated Heart Failure Syndrome

NCT00701519
View directory record Official record
Conditions
Sleep Apnea, Congestive Heart Failure, Heart Failure
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
1,600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 16, 2017 · Synced Oct 13, 2026, 10:44 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effective Conversion of Individuals at Risk

NCT05112757
View directory record Official record
Conditions
Obstructive Sleep Apnea, Atrial Fibrillation
Interventions
Smartphone application use
Other
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Race And CPAP Effectiveness

NCT01960465
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Continuous positive airway pressure
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 70 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Obstructive Sleep Apnea in World Trade Center Responders

NCT01753999
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Standard CPAP, CPAP - Flex
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Enrollment
317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
3
States / cities
Piscataway, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Oct 13, 2026, 10:44 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Effects of Mental Tasks on Breathing Patterns in Adults Using Chronic Opioids vs Non-opioid Users.

NCT07829055
View directory record Official record
Conditions
Opiod Use Disorder, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of Adaptive Servoventilation (ASV) in Patients With Central Sleep Apnea Due to Chronic Opioid Use

NCT01462084
View directory record Official record
Conditions
Obstructive Sleep Apnea, Central Sleep Apnea (Diagnosis), Chronic Opioid Use
Interventions
Adaptive servo-ventilation (ASV), Bi-Level PAP
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 13, 2026, 10:44 PM EDT
Not listed Not applicable Interventional

eXciteOSA for Treatment of Mild Obstructive Sleep Apnea

NCT05183009
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
eXciteOSA
Device
Lead sponsor
Signifier Medical Technologies
Industry
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
Birmingham, Alabama • Colorado Springs, Colorado • Lehigh Acres, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional

Effect of Myofunctional Therapy on OSA

NCT04608552
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
OMT Exercises, Nasal Breathing Exercises, Use of Nasal Lavage
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 13, 2026, 10:44 PM EDT
Withdrawn Not applicable Interventional

Initiation of Auto-adjusting CPAP for Newly Diagnosed OSA in Hospitalized Patients

NCT01556464
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Auto-adjusting CPAP
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Oct 13, 2026, 10:44 PM EDT
Not listed Phase 3 Interventional

Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome

NCT01427673
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overlap Syndrome
Interventions
Bipap procedure
Procedure
Lead sponsor
United States Air Force
Federal
Eligibility
35 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Wpafb, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 1, 2011 · Synced Oct 13, 2026, 10:44 PM EDT
Enrolling by invitation Not applicable Interventional

Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

NCT06614582
View directory record Official record
Conditions
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 23 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 13, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Validation of Sleep Apnea Screening Device

NCT02814227
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Zansors® sleep screening device
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Oct 13, 2026, 10:44 PM EDT