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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Obstructive Sleep Apnea (OSAS) Clear all
Completed Phase 2 Interventional Results available

Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial

NCT01187771
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
Laparoscopic Gastric Banding, Continuous Positive Airway Pressure
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Sep 22, 2026, 7:03 AM EDT
Recruiting Not applicable Interventional

OurSleepKit To Support CPAP Adherence

NCT06621511
View directory record Official record
Conditions
Obstructive Sleep Apnea, CPAP Treatment, Treatment Adherence
Interventions
OurSleepKit
Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Recruiting Not applicable Interventional

Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy

NCT05350332
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation, Percutaneous Phrenic Nerve Stimulation
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Active, not recruiting Phase 2 Interventional

Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea

NCT06776432
View directory record Official record
Conditions
Sleep Apnea
Interventions
Sivopixant, Placebo, Acetazolamide, SASS-001
Drug
Lead sponsor
Shionogi
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
La Jolla, California • Brandon, Florida • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

Nasal EPAP for Stroke Patients With Sleep Apnea: a Pilot Trial.

NCT01703663
View directory record Official record
Conditions
Ischemic Stroke, Obstructive Sleep Apnea
Interventions
EPAP
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 12, 2016 · Synced Sep 22, 2026, 7:03 AM EDT
Suspended No phase listed Observational Accepts healthy volunteers

Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet

NCT04946201
View directory record Official record
Conditions
Obstructive Sleep Apnea, Malocclusion
Interventions
Not listed
Lead sponsor
Mohamed Bazina
Other
Eligibility
10 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Sep 22, 2026, 7:03 AM EDT
Not yet recruiting Not applicable Interventional

Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).

NCT07613281
View directory record Official record
Conditions
Snoring, OSA - Obstructive Sleep Apnea
Interventions
Palatal Implant System
Device
Lead sponsor
Serene Sleep, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California • Evans, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Ambulatory Management for Veterans With Sleep Apnea

NCT00880165
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Continuous positive airway pressure apparatus
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 90 Years
Enrollment
296 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 20, 2014 · Synced Sep 22, 2026, 7:03 AM EDT
Completed No phase listed Observational

Screening Tools for Obstructive Sleep Apnea (OSA) in Hospitalized Medical Patients

NCT01340781
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Polysomnogram
Procedure
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 18, 2013 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

Clinical Study for the BONGO Device in the Treatment of Obstructive Sleep Apnea (OSA)

NCT02878590
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
BONGO DEVICE
Device
Lead sponsor
InnoMed Healthscience Inc.
Industry
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Alameda, California
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Motivational Enhancement - Acute Decompensated Heart Failure and OSA

NCT04752462
View directory record Official record
Conditions
Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
Interventions
Telemedicine Intensive Motivational Enhancement
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Sep 22, 2026, 7:03 AM EDT
Active, not recruiting Not applicable Interventional

3D Printer Modified CPAP Mask for Obstructive Sleep Apnea

NCT03932383
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Custom CPAP mask
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Sep 22, 2026, 7:03 AM EDT
Terminated Phase 4 Interventional

Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children

NCT00456339
View directory record Official record
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Prednisolone and amoxicillin/clavulanate
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Months to 12 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Sep 22, 2026, 7:03 AM EDT
Recruiting Not applicable Interventional

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils

NCT06258837
View directory record Official record
Conditions
Otolaryngological Disease, Obstructive Sleep Apnea
Interventions
DISE-Directed Surgery, Adenotonsillectomy
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
2 Years to 17 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Recruiting Not applicable Interventional

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

NCT04179981
View directory record Official record
Conditions
Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD, Overlap Syndrome, Quality of Life, Neurocognitive Function, Sleepiness, Elderly, Positive Airway Pressure
Interventions
Positive airway pressure, Conservative care (control arm)
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
668 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional Results available

TPAP for Comfort in OSA

NCT06264128
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
TPAP, CPAP
Device
Lead sponsor
SleepRes Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Effectiveness and Safety of cNEP in Ethnic Japanese With Obstructive Sleep Apnea

NCT03375905
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
cNEP
Device
Lead sponsor
Sommetrics, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kaneohe, Hawaii
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Sep 22, 2026, 7:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea

NCT00672737
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Remifentanil, Cold pain threshold and tolerance, Heat pain threshold and tolerance, Polysomnography
Drug · Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2017 · Synced Sep 22, 2026, 7:03 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

CPAP Population Management

NCT04559737
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Case Management
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD

NCT02641496
View directory record Official record
Conditions
Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
Interventions
CBT-OSA, Sleep Education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2024 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Impact of Automated Education and Follow-up Mechanisms on Patient Engagement

NCT02279901
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Telemedicine Education, IVR
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Sep 22, 2026, 7:03 AM EDT
Recruiting Phase 2 Interventional

DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.

NCT07635563
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
IHL-42X: 2.5 mg dronabinol + 125 mg acetazolamide, IHL-42X: 5 mg dronabinol + 125 mg acetazolamide, IHL-42X: 7.5 mg dronabinol + 125 mg acetazolamide, IHL-42X: 2.5 mg dronabinol + 250 mg acetazolamide, IHL-42X: 5 mg dronabinol + 250 mg acetazolamide, IHL-42X: 7.5 mg dronabinol + 250 mg acetazolamide, IHL-42X: 2.5 mg dronabinol + 375 mg acetazolamide, IHL-42X: 5 mg dronabinol + 375 mg acetazolamide, IHL-42X: 7.5 mg dronabinol + 375 mg acetazolamide, Placebo: Negative control
Drug
Lead sponsor
Incannex Healthcare Ltd
Industry
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
14
States / cities
Chula Vista, California • Brandon, Florida • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 22, 2026, 7:03 AM EDT
Completed No phase listed Observational

Revisiting Parental Survey for Screening for Obstructive Sleep Apnea in Patients Undergoing Polysomnography

NCT01914198
View directory record Official record
Conditions
Sleep Apnea
Interventions
Sleep apnea symptom survey
Other
Lead sponsor
Vidya Raman
Other
Eligibility
3 Years to 18 Years
Enrollment
948 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 4, 2018 · Synced Sep 22, 2026, 7:03 AM EDT
Completed Not applicable Interventional

Evidence-based Diagnosis and Management of Pediatric Obstructive Sleep Apnea in Primary Care

NCT02781376
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CHICA OSA, Snoring Identification Only
Other
Lead sponsor
Indiana University
Other
Eligibility
1 Year to 11 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Sep 22, 2026, 7:03 AM EDT