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ClinicalTrials.gov public records Last synced Oct 14, 2026, 10:44 PM EDT

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Showing 337–360 of 759 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) Clear all
Recruiting Not applicable Interventional

Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement

NCT07132307
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Mandibular advancement device (MAD)
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Withdrawn Phase 2 Interventional

Controlled Trial on Effect of Montelukast Treatment in Children With Obstructive Sleep Apnea Syndrome

NCT00599534
View directory record Official record
Conditions
Sleep Apnea
Interventions
Montelukast, Placebo
Drug
Lead sponsor
University of Louisville
Other
Eligibility
2 Years to 9 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Oct 14, 2026, 10:44 PM EDT
Terminated No phase listed Observational

Effect of Continuous Positive Airway Pressure (CPAP) Therapy on Changes of Blood Pressure Between Day and Night

NCT01865864
View directory record Official record
Conditions
Obstructive Sleep Apnea, Diurnal Blood Pressure
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2013 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study of the Comparison of the Upper Airway Dynamics of Oronasal vs Nasal Masks With PAP Treatment

NCT01939938
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Nasal and Oronasal PAP Mask
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 14, 2026, 10:44 PM EDT
Terminated Phase 4 Interventional Results available

Burden of Obstructive Sleep Apnea in Stroke (BOSAST)

NCT00952211
View directory record Official record
Conditions
Stroke, Obstructive Sleep Apnea
Interventions
CPAP, CPAP at sub-therapeutic pressure
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
45 Years to 85 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2016 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Pilairo Lab Market Research

NCT01824979
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP mask ( Pilairo), Other CPAP mask
Device · Procedure
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Burlingame, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 14, 2026, 10:44 PM EDT
Withdrawn No phase listed Observational

Tonsillectomy in Adults With Tonsillar Hypertrophy and Obstructive Sleep Apnea

NCT02204696
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Tonsillectomy
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
17 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 14, 2026, 10:44 PM EDT
Completed No phase listed Observational

Comparison of Standing Versus Supine 3D Cone Beam Computed Tomography in Patient With Obstructive Sleep Apnea

NCT04874727
View directory record Official record
Conditions
OSA, Sleep Apnea
Interventions
Mandible slacked and captured with Correct Plus™ Impression Material Superfast
Procedure
Lead sponsor
Manhattan Beach Orthodontics
Other
Eligibility
Not listed
Enrollment
6 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Manhattan Beach, California
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 14, 2026, 10:44 PM EDT
Active, not recruiting Not applicable Interventional

DISE: Phenotyping Obstruction Patterns

NCT05050383
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Pharyngeal Manometry
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional

Positive Airway Pressure (PAP) for Children With Down Syndrome (DS) and Obstructive Sleep Apnea Syndrome (OSAS)

NCT04132999
View directory record Official record
Conditions
Down Syndrome, Obstructive Sleep Apnea
Interventions
Family-informed intervention, Standard Clinical Care
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
6 Years to 18 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Miami, Florida • Cincinnati, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Phase 4 Interventional Results available

The Impact of Arousal Threshold in Obstructive Sleep Apnea

NCT02264353
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Donepezil, placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 14, 2026, 10:44 PM EDT
Recruiting Phase 4 Interventional

Improving Outcomes in Pediatric Obstructive Sleep Apnea With Computational Fluid Dynamics

NCT04991389
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
129-Xe
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Dex as Analgesic Adjuvant in OSA Patients

NCT03613558
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations?

NCT01184118
View directory record Official record
Conditions
Lung Disease
Interventions
FP 220 mcg 2 puffs BID
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Oct 14, 2026, 10:44 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pilot Study of the MultiSense Patch to Record Cardiopulmonary Data During Sleep and Wake Cycles

NCT02222103
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 14, 2026, 10:44 PM EDT
Withdrawn Not applicable Interventional

Dim Light at Night in Patients With Obstructive Sleep Apnea

NCT01853891
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
dim light at night
Other
Lead sponsor
Ulysses Magalang MD
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Phase 2 Interventional

Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP)

NCT05951023
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Eszopiclone 2 mg, Placebo
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 14, 2026, 10:44 PM EDT
Withdrawn Not applicable Interventional

Obstructive Sleep Apnea in Elective Orthopaedic Surgery

NCT03166462
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Total Knee Arthroplasty, Total Hip Arthroplasty
Interventions
Evaluation by Sleep Medicine Specialists
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Phase 3 Interventional

A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweight

NCT05929079
View directory record Official record
Conditions
Type 2 Diabetes, Obesity, Overweight, Obstructive Sleep Apnea
Interventions
Retatrutide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
1,152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
40
States / cities
Anniston, Alabama • Cullman, Alabama • Little Rock, Arkansas + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Active, not recruiting Not applicable Interventional

Evidence-based Pediatric Obstructive Sleep Apnea Detection

NCT05908110
View directory record Official record
Conditions
Obstructive Sleep Apnea of Child
Interventions
Health Communication Message
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
2 Years to 13 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Phase 2Phase 3 Interventional

Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention

NCT00662623
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
i-PAP, Usual Care (Standard Care)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Comparison Study of the ICON™ CPAP Series With and Without SensAwake™

NCT01831258
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
SensAwake On, SensAwake Off
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Glendale, Arizona • Macon, Georgia • Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2017 · Synced Oct 14, 2026, 10:44 PM EDT
Completed Not applicable Interventional Results available

Metabolic Impact of Intermittent CPAP

NCT02824263
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP withdrawal
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 75 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 14, 2026, 10:44 PM EDT
Recruiting Not applicable Interventional

Telehealth for Sleep Apnea: Effectiveness, Implementation, and Cost in the Military Health System

NCT07121452
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Sleep Navigator
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 64 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 14, 2026, 10:44 PM EDT